Donor-specific HLA-DQ antibodies may contribute to poor graft outcome after heart transplantation
CONCLUSION:HLA-DQ donor-specific antibodies were the most common type detected and may play a significant role in poor outcomes post-cardiac transplantation. This emphasizes the importance of HLA-DQ matching and monitoring for DSA formation in order to minimize post-transplantation immunological risk.  LIMITATIONS:Retrospective design comes with inherent biases, results from single institute, with a particularly young cohort. CONFLICT OF INTEREST:None.   (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - April 5, 2018 Category: General Medicine Tags: ISSUE 2 Source Type: research

Outcomes of common general surgery procedures for patients discharged over weekends at a tertiary care hospital in Saudi Arabia
CONCLUSION:Weekend discharge was not associated with higher readmission rates. Physicians may consider discharging post-operative patients over a weekend without an increased risk to the patient. Day of discharge, length of stay and increased patient age are not predictors of early readmission.  LIMITATIONS:Single-center study and retrospective. CONFLICT OF INTEREST: None.    (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - April 5, 2018 Category: General Medicine Tags: ISSUE 2 Source Type: research

Elevated fasting blood glucose, but not obesity, is associated with coronary artery disease in patients undergoing elective coronary angiography in a referral hospital in Jordan
CONCLUSIONS: Elevated FBG, but not obesity, predicted CAD in a Middle Eastern population. Improved prevention, detection and management of type 2 diabetes should be a priority in this setting.  LIMITATIONS:The cross-sectional design cannot control for temporal changes in risk factors and/or reverse causation.   CONFLICT OF INTEREST:None.  (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - April 5, 2018 Category: General Medicine Tags: ISSUE 2 Source Type: research

Endobronchial biopsy in the final diagnosis of chronic obstructive pulmonary disease and asthma: a clinicopathological study
CONCLUSIONS:The thickness of the RBM is the only reproducible histopathological feature to differentiate COPD from irreversible asthma. LIMITATIONS: The study included a limited number of patients. A qualitative approach was used to compare epithelial cell injury, inflammation, submucosal glandular and muscular hyperplasia.  CONFLICT OF INTEREST: None.    (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - April 5, 2018 Category: General Medicine Tags: ISSUE 2 Source Type: research

Comparison of cochlear duct length between the Saudi and non-Saudi populations
CONCLUSIONS:The CDL differed significantly according to side of the cochlea and sex, but not by age. Geographically and ethnically, the mean CDL for Saudis was significantly different from the CDL of subjects of some ethnic backgrounds, but not others. Due to this diversity, we recommend that the CDL be measured before cochlear implant surgery.  LIMITATIONS:All the measurements were done by one person, and the subjects’ physical measurements, such as height or head circumference, were not included. CONFLICT OF INTEREST:None.  (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - April 5, 2018 Category: General Medicine Tags: ISSUE 2 Source Type: research

Vitamin D deficiency in sickle cell disease patients in the Eastern Province of Saudi Arabia
CONCLUSIONS:VDD is highly prevalent in this population. Established vitamin D screening is a necessity, so that affected patients can be treated.  LIMITATIONS:Presence of residual confounders such as nutritional status, physical activity, lack of sun exposure, medications that alleviate SCD crises (such as hydroxyurea), and comorbid illnesses. The relationship between sickle cell disease genotype and vitamin D level was not analyzed. CONFLICT OF INTEREST:None.   (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - April 5, 2018 Category: General Medicine Tags: ISSUE 2 Source Type: research

Age at presentation of undescended testicles: a single-center study in Saudi Arabia
CONCLUSION: Despite the international recommendation of carrying out orchidopexy between the ages of 6-12 months, the targeted recommended time frame is not met in Saudi Arabia. This is mainly related to late referral age and the long waiting time for elective surgery. LIMITATIONS:Small sample size and retrospective design. CONFLICT OF INTEREST: None.    (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - April 5, 2018 Category: General Medicine Tags: ISSUE 2 Source Type: research

Turnover among Filipino nurses in Ministry of Health hospitals in Saudi Arabia: causes and recommendations for improvement
CONCLUSION:Managing nurse turnover can be implemented on the organizational as well as at MOH levels. The recommendations given by the participants provide direct targets to improve retention. LIMITATIONS:With convenience sampling, the sample is probably not representative of the Filipino nursing population. CONFLICT OF INTEREST: None.    (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - April 5, 2018 Category: General Medicine Tags: ISSUE 2 Source Type: research

Cerebrospinal fluid leakage after turbinate submucosal diathermy: an unusual complication
We describe the first reported case in the literature of an iatrogenic CSF fistula caused by SMDIT, an unusual and potentially fatal complication, and its surgical management.  SIMILAR CASES PUBLISHED: None. CONFLICT OF INTEREST: None.   (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - April 5, 2018 Category: General Medicine Tags: ISSUE 2 Source Type: research

Cerebrodpinal fluid leakage after turbinate submucosal diathermy: an unusual complication
We describe the first reported case in the literature of an iatrogenic CSF fistula caused by SMDIT, an unusual and potentially fatal complication, and its surgical management.  CONFLICT OF INTEREST: None.  (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - April 5, 2018 Category: General Medicine Tags: ISSUE 2 Source Type: research

Doppler ultrasonography in the diagnosis of Graves disease: a non-invasive, widely underutilized diagnostic tool
We present the case of a patient with Graves disease (GD) to draw attention to the prac­tical reliability of ultrasound (US) Doppler (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - March 28, 2018 Category: General Medicine Tags: ISSUE 4 Source Type: research

RE: Serum viral markers in Iranian patients with congenital bleeding disorder
  To The Editor: We have read with great interest the article of Dr Nassiri-Toosi in your journal1 re­garding the prevalence of hepatitis C infection in (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - March 28, 2018 Category: General Medicine Tags: ISSUE 4 Source Type: research

RE: Serum viral markers in Iranian patients with congenital bleeding disorder
(Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - March 28, 2018 Category: General Medicine Tags: VOLUME 38 Source Type: research

Left-sided Amyand hernia
To the Editor: Claudius Amyand, surgeon to King George II, was the first to describe in 1736 the presence of a perforated appendix within the (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - March 28, 2018 Category: General Medicine Tags: ISSUE 4 Source Type: research

Breast metastasis of small bowel carcinoid tumor misdiagnosed as primary breast cancer
  To the Editor: Carcinoid tumors are rare, but constitute the most common gastrointestinal neuroendocrine tumors.1 These tumors arise from enterochromaffin cells of the gastrointestinal tract. (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - March 28, 2018 Category: General Medicine Tags: ISSUE 4 Source Type: research