A 15-year-old girl with pancytopenia and congenital defects
(Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - March 27, 2018 Category: General Medicine Tags: ISSUE 4 Source Type: research

Experience with oral mexiletine in primary erythromelalgia in children
We present two cases of primary erythromelalgia both of whom presented with a history of several months of severe burning pain in both hands and feet. Both patients had received multiple pain medications with no improvement in symptoms. Rain was relieved by putting affected parts in ice cold water, which resulted in immersion injury of the affected parts. Both patients stopped taking part in school and social activities. We tried oral mexiletine, a class lb antiarrythmic agent, in view of its reported role in various chronic painful conditions. Dramatic improvement was observed with its use. Both patients improved after se...
Source: Annals of Saudi Medicine - March 27, 2018 Category: General Medicine Tags: ISSUE 4 Source Type: research

Forced eye closure-induced reflex seizure and non-ketotic hyperglycemia
We report an uncommon case of 53-year-old female patient with partial seizure induced by forced vol¬untary eye closure due to non-ketotic hyperglycemia. The initial laboratory tests showed an elevated blood glucose level of 550 mg/dL but no evidence of ketosis. Brain magnetic resonance imaging was normal. When the blood glucose levels decreased slowly to about 150 mg/dL in five days, the seizures ended completely. No anticonvulsants were used. Since seizures are generally refractory to antiepileptic medication, control of blood glucose is essential. Ann Saudi Med 2009; 29(4): 313-315 (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - March 27, 2018 Category: General Medicine Tags: ISSUE 4 Source Type: research

Gender differences in mortality among ST elevation myocardial infarction patients in Malaysia from 2006 to 2013
CONCLUSION: Gender differences existed in the baseline characteristics, associated risk factors, clinical presentation and outcomes among STEMI patients. For STEMI females, the rate of mortality was twice that of males. Once they reach menopausal age, when there is less protection from the estrogen hormone and there are other risk factors, menopausal females are at increased risk for STEMI. LIMITATION:Retrospective registry data with inter-hospital variation.   (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - February 8, 2018 Category: General Medicine Tags: ISSUE 1 Source Type: research

Association between the mode of transport and in-hospital medical complications in trauma patients: findings from a level-I trauma center in Saudi Arabia
CONCLUSION:Multiple factors may influence this unexpected finding, such as distance to health care set.tings, the belief that PT is faster or lack of knowledge of the EMS contact number. Further efforts are needed to raise awareness of the importance of using EMS to transport trauma patients to hospitals. Prevention programs to reduce traffic crashes may facilitate reduction in traumatic injuries and associated complications. LIMITATIONS:Retrospective and conducted in one center only.    (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - February 8, 2018 Category: General Medicine Tags: ISSUE 1 Source Type: research

Delirium and correlates of delirium among newly admitted elderly patients: a cross-sectional study in a Saudi general hospital
CONCLUSIONS: Delirium was common and frequently not recognized in elderly patients admitted to the hospital. Administration of the CAM was very helpful in identifying delirium at admission. LIMITATIONS:The main limitation of our study was the relatively small number of patients which might have limited the power to detect some associations.   (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - February 8, 2018 Category: General Medicine Tags: ISSUE 1 Source Type: research

Psychometric Arabic Sino-Nasal Outcome Test-22: validation and translation in chronic rhinosinusitis patients
CONCLUSION: This is the first validated Arabic version of SNOT-22. The instrument can be used among the Arabic population. LIMITATIONS: No subjects from other Arab countries.   (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - February 8, 2018 Category: General Medicine Tags: ISSUE 1 Source Type: research

Descemet stripping automated endothelialkeratoplasty (DSAEK) versus repeat penetrating keratoplasty (PKP) to manage eyes with failed corneal graft
CONCLUSIONS: DSAEK and PKP for previously failed corneal graft resulted in similar BCVA 6 months after repeat surgery. However, the visual outcomes were less promising with both types of surgeries. The lower complication rate and surgical ease may favor DSAEK over PKP in managing failed grafts. LIMITATIONS: Small sample, retrospective study.   (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - February 8, 2018 Category: General Medicine Tags: ISSUE 1 Source Type: research

Sleep disorders as primary and secondary factors in relation with daily functioning in medical students
CONCLUSIONS: Insufficient sleep is a common issue in medical students and a number of sleep disorders were found. The results suggest that sleep disorders could have negative impacts on the daily functioning of students. LIMITATIONS:The study findings may not be generalizable because sociocultural characteristics of the sample may differ from the general population.    (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - February 8, 2018 Category: General Medicine Tags: ISSUE 1 Source Type: research

The endangered clinician-investigator profession in Saudi Arabia: curricular attention is required
(Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - February 8, 2018 Category: General Medicine Tags: ISSUE 1 Source Type: research

Nonmelanoma skin cancer in Saudi Arabia: single center experience
CONCLUSIONS: BCC and SCC are uncommon but not rare. However, skin cancers are underreported in in our population. NMSC in individuals younger than 50 years of age requires more careful evaluation of possible risk factors. LIMITATIONS:Retrospective in a single tertiary care setting.   (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - January 21, 2018 Category: General Medicine Tags: ISSUE 1 Source Type: research

Nonmelanoma skin cancer in Saudi Arabia: single center experience
CONCLUSIONS: BCC and SCC are uncommon but not rare. However, skin cancers are underreported in in our population. NMSC in individuals younger than 50 years of age requires more careful evaluation of pos.sible risk factors. LIMITATIONS:Retrospective in a single tertiary care setting.   (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - January 21, 2018 Category: General Medicine Tags: AHEAD OF PRINT Source Type: research

B cell aplasia and hypogammaglobulinemia associated with levetiracetam
We report a 45-year-old female who developed hypogammaglobulinemia and B cell aplasia during LEV treatment. The Naranjo probability score for an adverse drug reaction was 6. After LEV discontinuation, the number of B cells gradually increased and reached normal levels within two months. This case suggests that monitoring of immunoglobulin levels and lymphocyte subsets analysis is important in patients treated with LEV, especially in cases of prolonged infections.  SIMILAR CASES PUBLISHED: 1   (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - January 9, 2018 Category: General Medicine Tags: ISSUE 1 Source Type: research

The Saudi Diabetic Kidney Disease study (Saudi-DKD): clinical characteristics and biochemical parameters
CONCLUSION: Diabetic nephropathy is associated with insulin resistance, changes in liver enzymes and uric acid in addition to abnormalities in the red blood cell count and red blood cell shape that warrant frequent monitoring among patients with diabetic kidney disease. LIMITATIONS: Cross-sectional study design and exclusion of patients with some risk factors.   (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - January 3, 2018 Category: General Medicine Tags: ISSUE 1 Source Type: research