Donor-specific HLA-DQ antibodies may contribute to poor graft outcome after heart transplantation

CONCLUSION:HLA-DQ donor-specific antibodies were the most common type detected and may play a significant role in poor outcomes post-cardiac transplantation. This emphasizes the importance of HLA-DQ matching and monitoring for DSA formation in order to minimize post-transplantation immunological risk.  LIMITATIONS:Retrospective design comes with inherent biases, results from single institute, with a particularly young cohort. CONFLICT OF INTEREST:None.  
Source: Annals of Saudi Medicine - Category: General Medicine Tags: ISSUE 2 Source Type: research