Leproma's dermoscopy,
Abstract In situations in when a dermoscopic record of a large lesion is desirable, the resulting images are usually restricted to a small field of view due to the limited diameter of dermatoscope lenses. This limitation often produces several photographs separately, thus losing the possibility of a single-image global evaluation. In these case reports, we show examples of a recently published image montage technique called Wide Area Digital Dermoscopy, in this case, applied to basal cell carcinomas. (Source: Anais Brasileiros de Dermatologia)
Source: Anais Brasileiros de Dermatologia - July 24, 2020 Category: Dermatology Source Type: research

Wide area digital dermoscopy applied to basal cell carcinoma,
Abstract In situations in when a dermoscopic record of a large lesion is desirable, the resulting images are usually restricted to a small field of view due to the limited diameter of dermatoscope lenses. This limitation often produces several photographs separately, thus losing the possibility of a single-image global evaluation. In these case reports, we show examples of a recently published image montage technique called Wide Area Digital Dermoscopy, in this case, applied to basal cell carcinomas. (Source: Anais Brasileiros de Dermatologia)
Source: Anais Brasileiros de Dermatologia - July 24, 2020 Category: Dermatology Source Type: research

Systemic sporotrichosis in an alcoholic patient,
Abstract A 44-year-old male patient presented with nodules that evolved with inflammation, following drainage of seropurulent secretion and ulceration. The patient had a 6 year-history of alcohol addiction and reported contact with cats. At the physical examination, the patient had skin-colored and erythematous nodules, and ulcers covered with thick, blackened crusts on the face, trunk and limbs. A culture of a nodule fluid revealed growth of Sporotrix sp. He also had pulmonary involvement and therefore the disease was classified as systemic sporotrichosis, a rare form that usually affect patients infected with HIV. Chroni...
Source: Anais Brasileiros de Dermatologia - July 24, 2020 Category: Dermatology Source Type: research

Pseudomycetoma of the scalp caused by Microsporum canis,
We present a 24-year-old man with an exuberant tumor in the occipital region with fistula, whose histopathological examination evidenced grains composed of hyaline hyphae and the culture for fungi isolated the agent Microsporum canis. Combined treatment of surgical excision followed by oral griseofulvin for two years was performed, with resolution of the condition. (Source: Anais Brasileiros de Dermatologia)
Source: Anais Brasileiros de Dermatologia - July 24, 2020 Category: Dermatology Source Type: research

Update on vasculitis: an overview and dermatological clues for clinical and histopathological diagnosis - part I,
This article reviews the Chapel-Hill 2012 classification, etiology, recent insights in pathophysiology, some important dermatological clues for the diagnosis and summarizes treatment of some of these complex vasculitis syndromes. (Source: Anais Brasileiros de Dermatologia)
Source: Anais Brasileiros de Dermatologia - July 24, 2020 Category: Dermatology Source Type: research

Osteonevus of Nanta: a case report in a combined melanocytic nevus,
We report a case of osteonevus of Nanta in combined nevus, possibly the first description of this association. (Source: Anais Brasileiros de Dermatologia)
Source: Anais Brasileiros de Dermatologia - July 24, 2020 Category: Dermatology Source Type: research

Intravascular histiocytosis: case report of a rare disease probably associated with silicone breast implant,
We describe a case of a 55 year-old female patient presenting erythematous/purple patches on the breasts, back and limbs. She previously presented ductal carcinoma in the right breast in 2006 which was treated with mastectomy and proceeded to silicone breast implant in 2009. Clinical hypothesis was telangiectatic metastatic carcinoma. Histopathology showed vascular ectasia, thrombosis and recanalization of upper dermis small vessels. On immunohistochemistry, intravascular cells were CD 68+ and negative for estrogen and progesterone receptors, CK7, EMA and AE1/AE3 and endothelial cells were CD64+, leading to the diagnosis o...
Source: Anais Brasileiros de Dermatologia - July 24, 2020 Category: Dermatology Source Type: research

Disseminated tuberculosis associated with reactive arthritis of Poncet in an immunocompetent patient,
We report a previously healthy 23-year-old male patient with watery diarrhea associated with erythematous ulcers on the lower limbs and oligoarthritis of the hands. Histopathological examination of the skin showed epithelioid granulomatous process with palisade granulomas and central caseous necrosis. AFB screening by Ziehl-Neelsen staining showed intact bacilli, the culture was positive for Mycobacterium tuberculosis, and colonoscopy revealed multiple shallow ulcers. Disseminated tuberculosis associated with reactive Poncet arthritis was diagnosed, with an improvement of the clinical and skin condition after appropriate t...
Source: Anais Brasileiros de Dermatologia - July 24, 2020 Category: Dermatology Source Type: research

A case of facial atrophic sarcoidosis in an adolescent, successfully treated with the combination of prednisone and hydroxychloroquine,
We report a case of 13-year-old male patient with a facial atrophic sarcoidosis who was successfully treated with the combination of prednisone and hydroxychloroquine. (Source: Anais Brasileiros de Dermatologia)
Source: Anais Brasileiros de Dermatologia - July 24, 2020 Category: Dermatology Source Type: research

Acquired reactive perforating collagenosis in association with prostate adenocarcinoma, chronic lymphocytic leukemia, and Graves' disease,
Abstract Acquired reactive perforating collagenosis is a rare skin disorder characterized by the presence of umbilicated pruritic papules and nodules. Transepidermal elimination of altered and perforating bundles of basophilic collagen from the epidermis is a characteristic histologic feature of acquired reactive perforating collagenosis. Along with its well-known association with systemic diseases such as diabetes mellitus, chronic renal failure, and dermatomyositis, there are reports of acquired reactive perforating collagenosis being associated with malignancies. Herein, we present a case of acquired reactive perforatin...
Source: Anais Brasileiros de Dermatologia - July 24, 2020 Category: Dermatology Source Type: research

Tinea capitis: dermoscopy and calcium fluorescent microscopy as highly efficient and precise diagnostic tools
Abstract Tinea capitis comprising of tinea favosa and kerion is mostly seen in school-aged children. Some tinea capitis often presented with insignificant findings under the naked eyes are easily overlooked. The authors describe an unusual case of tinea capitis caused by Trichophyton violaceum. The patient was an 8-year-old girl, with a history of pruritus on the scalp for more than one year. A diagnosis of tinea capitis was confirmed by clinical examination aided by dermoscopy, calcium fluorescent microscopy and culture. Comma and corkscrew hairs are two specific dermoscopic patterns of tinea capitis. The patient was trea...
Source: Anais Brasileiros de Dermatologia - July 24, 2020 Category: Dermatology Source Type: research

Validation of an algorithm based on clinical, histopathological and immunohistochemical data for the diagnosis of early-stage mycosis fungoides,
Conclusions: Application of the Pimpinelli et al. algorithm, even in an incomplete form, increased the percentage of cases diagnosed as mycosis fungoides. Routine application of the algorithm may contribute to earlier and specific management and improvement of the patients' outcome. (Source: Anais Brasileiros de Dermatologia)
Source: Anais Brasileiros de Dermatologia - July 24, 2020 Category: Dermatology Source Type: research

A randomized half-body, double blind, controlled trial on the effects of a pH-modified moisturizer vs. standard moisturizer in mild to moderate atopic dermatitis,
Conclusion: Moisturization is beneficial for atopic dermatitis; u se of physiologically compatible pH moisturizer is promising. (Source: Anais Brasileiros de Dermatologia)
Source: Anais Brasileiros de Dermatologia - July 24, 2020 Category: Dermatology Source Type: research

Quantification of mitochondrial DNA damage and copy number in circulating blood of patients with systemic sclerosis by a qPCR-based assay,
Conclusion: These data suggest that alteration in mtDNAcn and increased oxidative DNA damage may be involved in the pathogenesis of systemic sclerosis. (Source: Anais Brasileiros de Dermatologia)
Source: Anais Brasileiros de Dermatologia - July 24, 2020 Category: Dermatology Source Type: research

Different distribution patterns of plasmacytoid dendritic cells in discoid lupus erythematosus and lichen planopilaris demonstrated by CD123 immunostaining,
Conclusions: We suggest that a plasmacytoid dendritic cells cluster of 10 cells or more is highly specific for distinguishing discoid lupus erythematosus from lichen planopilaris. It also appears that CD123 immunolabeling is valuable in both active and late stages of the disease. (Source: Anais Brasileiros de Dermatologia)
Source: Anais Brasileiros de Dermatologia - July 24, 2020 Category: Dermatology Source Type: research