Emtricitabine/Tenofovir disoproxil fumarate
TRUVADA tablets are fixed dose combination tablets containing emtricitabine and tenofovir disoproxil fumarate. EMTRIVA is the brand name for emtricitabine, a synthetic nucleoside analog of cytidine. Tenofovir disoproxil fumarate (tenofovir DF) is converted in vivo to tenofovir, an acyclic nucleoside phosphonate (nucleotide) analog of adenosine 5′-monophosphate. Both emtricitabine and tenofovir exhibit inhibitory activity against HIV-1 reverse transcriptase.
TRUVADA tablets are for oral administration. Each film-coated tablet contains 200 mg of emtricitabine and 300 mg of tenofovir disoproxil fumarate, (which is equiv...
Source: Aids Info Drugs - February 16, 2016 Category: Drugs & Pharmacology Source Type: research
Emtricitabine
EMTRIVA® is the brand name of emtricitabine, a synthetic nucleoside analog with activity against human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. The chemical name of emtricitabine is 5-fluoro-1-(2R,5S)-[2-(hydroxymethyl)-1,3oxathiolan-5-yl]cytosine. Emtricitabine is the (-) enantiomer of a thio analog of cytidine, which differs from other cytidine analogs in that it has a fluorine in the 5-position.
EMTRIVA is available as capsules or as an oral solution.
EMTRIVA Capsules are for oral administration. Each capsule contains 200 mg of emtricitabine and the inactive ingredients, crospovidone, magnesium s...
Source: Aids Info Drugs - February 16, 2016 Category: Drugs & Pharmacology Source Type: research
Didanosine
, a synthetic antiretroviral agent, is a nucleoside reverse transcriptase inhibitor. [#] Didanosine, a synthetic antiretroviral agent, is a synthetic analogue of deoxyadenosine, a naturally occurring purine nucleoside. Didanosine differs from deoxyadenosine in that the 3'-hydroxyl group on the ribose moiety is replaced with hydrogen. [#] (Source: Aids Info Drugs)
Source: Aids Info Drugs - February 16, 2016 Category: Drugs & Pharmacology Source Type: research
Abacavir/Lamivudine/ Zidovudine
Abacavir/lamivudine/zidovudine (Trizivir) is a fixed-dose tablet that contains three synthetic nucleoside analogues: abacavir sulfate, lamivudine, and zidovudine. Each tablet contains abacavir sulfate 300 mg, lamivudine 150 mg, and zidovudine 300 mg, each of which inhibits HIV-1 viral reverse transcriptase. [#] (Source: Aids Info Drugs)
Source: Aids Info Drugs - February 16, 2016 Category: Drugs & Pharmacology Source Type: research
Abacavir/Lamivudine
EPZICOM Tablets contain the following 2 synthetic nucleoside analogues: abacavir sulfate (ZIAGEN, also a component of TRIZIVIR) and lamivudine (also known as EPIVIR or 3TC) with inhibitory activity against HIV-1.
EPZICOM Tablets are for oral administration. Each orange, film-coated tablet contains the active ingredients 600 mg of abacavir as abacavir sulfate and 300 mg of lamivudine, and the inactive ingredients magnesium stearate, microcrystalline cellulose, and sodium starch glycolate. The tablets are coated with a film (OPADRY® orange YS-1-13065-A) that is made of FD&C Yellow No. 6, hypromellose, polyethylene gl...
Source: Aids Info Drugs - February 16, 2016 Category: Drugs & Pharmacology Source Type: research
Abacavir
is a synthetic analogue of guanine, a naturally occurring purine nucleoside. It differs structurally from other reverse transcriptase inhibitors (didanosine, lamivudine, stavudine, zalcitabine, and zidovudine) in that it is a carbocyclic nucleoside analogue rather than a dideoxynucleoside analogue. [#] (Source: Aids Info Drugs)
Source: Aids Info Drugs - February 16, 2016 Category: Drugs & Pharmacology Source Type: research
Rilpivirine
, also known as Edurant, is a non-nucleoside reverse transcriptase inhibitor (NNRTI) of human immunodeficiency virus type 1 (HIV-1). [#] (Source: Aids Info Drugs)
Source: Aids Info Drugs - February 16, 2016 Category: Drugs & Pharmacology Source Type: research
Nevirapine
is a dipyridodiazepine derivative non-nucleoside reverse transcriptase inhibitor (NNRTI). [#] (Source: Aids Info Drugs)
Source: Aids Info Drugs - February 16, 2016 Category: Drugs & Pharmacology Source Type: research
Etravirine
, also known as Intelence or TMC125, is a diarylpyrimidine (DAPY) derivative with potent in vitro activity against HIV. [#]
In vitro, etravirine has equipotent activity against wild-type HIV and NNRTI-resistant variants that encode L100I, K103N, Y181C, Y188L, and G190A/S mutations. [#] (Source: Aids Info Drugs)
Source: Aids Info Drugs - February 16, 2016 Category: Drugs & Pharmacology Source Type: research
Efavirenz
, also known as EFV, is an HIV-1 specific, non-nucleoside reverse transcriptase inhibitor (NNRTI). [#] (Source: Aids Info Drugs)
Source: Aids Info Drugs - February 16, 2016 Category: Drugs & Pharmacology Source Type: research
Delavirdine
mesylate is a bis(heteroaryl)piperazine (BHAP) derivative nonnucleoside reverse transcriptase inhibitor (NNRTI). [#] (Source: Aids Info Drugs)
Source: Aids Info Drugs - February 16, 2016 Category: Drugs & Pharmacology Source Type: research
Raltegravir
ISENTRESS contains raltegravir potassium, a human immunodeficiency virus integrase strand transfer inhibitor.
Each film-coated tablet of ISENTRESS for oral administration contains 434.4 mg of raltegravir potassium (as salt), equivalent to 400 mg of raltegravir (free phenol) and the following inactive ingredients: microcrystalline cellulose, lactose monohydrate, calcium phosphate dibasic anhydrous, hypromellose 2208, poloxamer 407 (contains 0.01% butylated hydroxytoluene as antioxidant), sodium stearyl fumarate, magnesium stearate. In addition, the film coating contains the following inactive ingredients: polyvinyl alcohol,...
Source: Aids Info Drugs - February 16, 2016 Category: Drugs & Pharmacology Source Type: research
Maraviroc
, also known as Selzentry, is a chemokine receptor antagonist that acts as an entry inhibitor. It is designed to prevent HIV infection of CD4 cells by blocking chemokine receptor 5 (CCR5), a coreceptor necessary for HIV entry, from binding to HIV. [#] (Source: Aids Info Drugs)
Source: Aids Info Drugs - February 16, 2016 Category: Drugs & Pharmacology Source Type: research
Enfuvirtide
is an inhibitor of the fusion of HIV-1 with CD4 cells. It is a linear 36-amino acid synthetic peptide with an acetylated N-terminus and a carboxamide C-terminus. It is composed of naturally occurring L-amino acid residues. [#] (Source: Aids Info Drugs)
Source: Aids Info Drugs - February 16, 2016 Category: Drugs & Pharmacology Source Type: research
Emtricitabine / Rilpivirine / Tenofovir disoproxil fumarate
Complera is a fixed-dose combination tablet containing emtricitabine, rilpivirine hydrochloride, and tenofovir disoproxil fumarate. Emtriva is the brand name for emtricitabine, a synthetic nucleoside analog of cytidine. Edurant is the brand name for rilpivirine, a non-nucleoside reverse transcriptase inhibitor. Viread is the brand name for tenofovir DF, which is converted in vivo to tenofovir, an acyclic nucleoside phosphonate (nucleotide) analog of adenosine 5′-monophosphate. Viread and Emtriva are the components of Truvada. (Source: Aids Info Drugs)
Source: Aids Info Drugs - February 16, 2016 Category: Drugs & Pharmacology Source Type: research
