Resting state perfusion in the language network is linked to formal thought disorder and poor functional outcome in schizophrenia
ConclusionsDistinguishable associations of rCBF with FTD dimensions point to distinct underlying pathophysiology. The location of aberrant perfusion patterns suggests that negative FTD might reflect defective access to semantic memory while positive FTD likely reflects defective suppression of irrelevant information during increased speech production. Finally, the neural correlates of thought block were also predictive of poor functional outcome. Thus, functional outcome and distinct FTD dimensions may share some pathophysiology. (Source: Acta Psychiatrica Scandinavica)
Source: Acta Psychiatrica Scandinavica - September 2, 2017 Category: Psychiatry Authors: K. Stegmayer, M. Stettler, W. Strik, A. Federspiel, R. Wiest, S. Bohlhalter, S. Walther Tags: Original Article Source Type: research
Comment on Vitamin D serum levels are cross ‐sectionally but not prospectively associated with late‐life depression
(Source: Acta Psychiatrica Scandinavica)
Source: Acta Psychiatrica Scandinavica - September 1, 2017 Category: Psychiatry Authors: T. C. Griffen Tags: Letter to the Editor Source Type: research
The role of stress ‐regulation genes in moderating the association of stress and daily‐life psychotic experiences
ConclusionIndividual differences in relevant stress‐regulation systems interact with both distal and proximal psychosocial stressors in shaping the daily‐life manifestation of PEs across the psychosis continuum. (Source: Acta Psychiatrica Scandinavica)
Source: Acta Psychiatrica Scandinavica - September 1, 2017 Category: Psychiatry Authors: P. Crist óbal‐Narváez, T. Sheinbaum, I. Myin‐Germeys, T. R. Kwapil, M. Castro‐Catala, T. Domínguez‐Martínez, A. Racioppi, M. Monsonet, L. Hinojosa‐Marqués, R. Winkel, A. Rosa, N. Barrantes‐Vidal Tags: Original Article Source Type: research
Does persisting fear sustain catatonia?
ConclusionThe signs of catatonia are adaptations to persistent fear, akin to tonic immobilization. The relief afforded by sedation supports this interpretation. (Source: Acta Psychiatrica Scandinavica)
Source: Acta Psychiatrica Scandinavica - September 1, 2017 Category: Psychiatry Authors: M. Fink, E. Shorter Tags: Clinical Overview Source Type: research
Incidence of early anxiety aggravation in trials of selective serotonin reuptake inhibitors in depression
ConclusionWhereas an anxiety‐reducing effect of SSRIs is notable already during the first week of treatment, these drugs may also elicit an early increase in anxiety in susceptible subjects that however does not predict a poor subsequent response to treatment. (Source: Acta Psychiatrica Scandinavica)
Source: Acta Psychiatrica Scandinavica - August 31, 2017 Category: Psychiatry Authors: J. N äslund, F. Hieronymus, J. F. Emilsson, A. Lisinski, S. Nilsson, E. Eriksson Tags: Original Article Source Type: research
Sociodemographic, clinical, and functional long ‐term outcomes in adolescents and young adults with mental disorders
ConclusionsOur findings emphasize the importance of effective treatment of mental disorders to prevent unfavorable long‐term outcomes in various life domains. (Source: Acta Psychiatrica Scandinavica)
Source: Acta Psychiatrica Scandinavica - August 31, 2017 Category: Psychiatry Authors: E. Asselmann, H. ‐U. Wittchen, R. Lieb, K. Beesdo‐Baum Tags: Original article Source Type: research
The effect of adjunctive telmisartan treatment on psychopathology and cognition in patients with schizophrenia
ConclusionThe present study suggests that adjunctive treatment with telmisartan may improve schizophrenia symptoms. Future trials with larger sample sizes and longer treatment durations are warranted. (Source: Acta Psychiatrica Scandinavica)
Source: Acta Psychiatrica Scandinavica - August 29, 2017 Category: Psychiatry Authors: X. Fan, X. Song, M. Zhao, L. F. Jarskog, R. Natarajan, N. Shukair, O. Freudenreich, D. C. Henderson, D. C. Goff Tags: Original article Source Type: research
Increased illness burden in women with comorbid bipolar and premenstrual dysphoric disorder: data from 1 099 women from STEP ‐BD study
ConclusionsThe comorbidity between PMDD and BD is associated with worse clinical outcomes and increased illness burden. (Source: Acta Psychiatrica Scandinavica)
Source: Acta Psychiatrica Scandinavica - August 28, 2017 Category: Psychiatry Authors: A. Slyepchenko, B. N. Frey, B. Lafer, A. A. Nierenberg, G. S. Sachs, R. S. Dias Tags: Original Article Source Type: research
Association between the antioxidant uric acid and depression and antidepressant medication use in 96 989 individuals
ConclusionHigh plasma levels of uric acid were associated with low risk of depression hospitalization and antidepressant medication use. (Source: Acta Psychiatrica Scandinavica)
Source: Acta Psychiatrica Scandinavica - August 28, 2017 Category: Psychiatry Authors: M. K. Wium ‐Andersen, C. J. Kobylecki, S. Afzal, B. G. Nordestgaard Tags: Original Article Source Type: research
Trajectories of posttraumatic growth among US military veterans: a 4 ‐year nationally representative, prospective cohort study
ConclusionPosttraumatic growth is a dynamic process with divergent trajectories. Developing interventions that target certain psychosocial factors may help trauma survivors maintain PTG over time. (Source: Acta Psychiatrica Scandinavica)
Source: Acta Psychiatrica Scandinavica - August 28, 2017 Category: Psychiatry Authors: J. Tsai, R. H. Pietrzak Tags: Original Article Source Type: research
‘No cognitive‐enhancing effect of GLP‐1 receptor agonism in antipsychotic‐treated, obese patients with schizophrenia’: authors' response
(Source: Acta Psychiatrica Scandinavica)
Source: Acta Psychiatrica Scandinavica - August 28, 2017 Category: Psychiatry Authors: B. H. Ebdrup, P. L. Ish øy, B. Fagerlund, B. V. Broberg, N. Bak, F. K. Knop, B. Y. Glenthøj Tags: Letter to the Editor Source Type: research
Reply
(Source: Acta Psychiatrica Scandinavica)
Source: Acta Psychiatrica Scandinavica - August 28, 2017 Category: Psychiatry Authors: Rebecca Schneibel, Gregor Wilbertz, Christine Scholz, Manuel Becker, Tom Bschor, Dirk Schmoll Tags: Letter to the Editor Source Type: research
Infectious and immunogenetic factors in bipolar disorder
ConclusionInfection has emerged as a potential preventable cause of morbidity in BD, urging the need to better investigate components of the host–pathogen interaction in patients and at‐risk subjects, and thus opening the way to novel therapeutic opportunities. (Source: Acta Psychiatrica Scandinavica)
Source: Acta Psychiatrica Scandinavica - August 21, 2017 Category: Psychiatry Authors: J. Oliveira, A. J. Oliveira ‐Maia, R. Tamouza, A. S. Brown, M. Leboyer Tags: Review Source Type: research
Persistent increase in TNF and IL ‐1 markers in severe mental disorders suggests trait‐related inflammation: a one year follow‐up study
ConclusionPersistently increased sTNF‐R1 and IL‐1Ra after one year in patients with severe mental disorders primarily reflecting data from the schizophrenia group may suggest that inflammation is a trait phenomenon, and not only the result of stress‐related mechanisms associated with acute episodes. (Source: Acta Psychiatrica Scandinavica)
Source: Acta Psychiatrica Scandinavica - August 16, 2017 Category: Psychiatry Authors: R. H. M ørch, I. Dieset, A. Færden, S. Hope, M. Aas, M. Nerhus, E. S. Gardsjord, M. Haram, R. S. Falk, I. Joa, G. Morken, I. Agartz, P. Aukrust, S. Djurovic, I. Melle, T. Ueland, O. A. Andreassen Tags: Original article Source Type: research
Genomewide DNA methylation analysis in combat veterans reveals a novel locus for PTSD
ConclusionThese data highlight the role of DNA methylation as biomarkers of PTSD. The results support the role of previous candidates and uncover novel genes associated with PTSD, such as DOCK2. This study contributes to our understanding of the biological underpinnings of PTSD. (Source: Acta Psychiatrica Scandinavica)
Source: Acta Psychiatrica Scandinavica - August 10, 2017 Category: Psychiatry Authors: D. Mehta, D. Bruenig, T. Carrillo ‐Roa, B. Lawford, W. Harvey, C. P. Morris, A. K. Smith, E. B. Binder, R. McD Young, J. Voisey Tags: Original article Source Type: research
