Codeine consumption from over-the-counter anti-cough syrup in Taiwan: A useful indicator for opioid abuse.
CONCLUSION: The fairly low and stable consumption of prescription codeine suggested that physicians in Taiwan were careful in prescribing codeine, and that the medical demand for codeine was stable. The large variance in OTC codeine consumption suggested that a minority of consumers purchased significant quantities of codeine for non-medical purposes. Although opioids in cough syrup were not a large part of overall consumption and thus not widely abused, the data revealed that OTC codeine-containing cough syrup may serve as an indicator of potential drug abuse in the population as compared to prescription codeine.
...
Source: Acta Anaesthesiologica Taiwanica - November 29, 2015 Category: Anesthesiology Authors: Lo MY, Ong MW, Lin JG, Sun WZ Tags: Acta Anaesthesiol Taiwan Source Type: research
The law of Yin and Yang for controlled drugs ecosystem: Maximal analgesia with minimal abuse.
PMID: 26631426 [PubMed - as supplied by publisher] (Source: Acta Anaesthesiologica Taiwanica)
Source: Acta Anaesthesiologica Taiwanica - November 26, 2015 Category: Anesthesiology Authors: Sun WZ, Taiwan Pain Forum Tags: Acta Anaesthesiol Taiwan Source Type: research
Age correlates with hypotension during propofol-based anesthesia for endoscopic retrograde cholangiopancreatography.
CONCLUSION: Hypotension was the most frequent anesthetic complication during procedure under propofol-based deep sedation, but this method was safe and effective under appropriate monitoring. Age is the strongest predictor of hypotension and therefore propofol-based deep sedation should be conducted with caution in the elderly.
PMID: 26627000 [PubMed - as supplied by publisher] (Source: Acta Anaesthesiologica Taiwanica)
Source: Acta Anaesthesiologica Taiwanica - November 25, 2015 Category: Anesthesiology Authors: Khoi CS, Wong JJ, Wang HC, Lu CW, Lin TY Tags: Acta Anaesthesiol Taiwan Source Type: research
Clinical study to evaluate the role of preoperative dexmedetomidine in attenuation of hemodynamic response to direct laryngoscopy and tracheal intubation.
CONCLUSION: Administration of a single preinduction intravenous dose of dexmedetomidine of 0.5 μg/kg resulted in significant attenuation of the rise in the heart rate, systolic blood pressure, diastolic blood pressure, and mean blood pressure, until 5 minutes postintubation. It significantly reduced the dose requirements of propofol for induction and caused minimal side effects.
PMID: 26510669 [PubMed - as supplied by publisher] (Source: Acta Anaesthesiologica Taiwanica)
Source: Acta Anaesthesiologica Taiwanica - October 26, 2015 Category: Anesthesiology Authors: Kumari K, Gombar S, Kapoor D, Sandhu HS Tags: Acta Anaesthesiol Taiwan Source Type: research
One-hand maneuver to facilitate flexible fiber-optic bronchoscope-guided nasotracheal intubation in sedated patients.
PMID: 26476788 [PubMed - as supplied by publisher] (Source: Acta Anaesthesiologica Taiwanica)
Source: Acta Anaesthesiologica Taiwanica - September 28, 2015 Category: Anesthesiology Authors: Shih CK, Wu CC, Ji TT Tags: Acta Anaesthesiol Taiwan Source Type: research
Response surface models in the field of anesthesia: A crash course.
Abstract
Drug interaction is fundamental in performing anesthesia. A response surface model (RSM) is a very useful tool for investigating drug interactions. The methodology appeared many decades ago, but did not receive attention in the field of anesthesia until the 1990s. Drug investigations typically start with pharmacokinetics, but it is the effects on the body clinical anesthesiologists really care about. Typically, drug interactions are divided into additive, synergistic, or infra-additive. Traditional isobolographic analysis or concentration-effect curve shifts are limited to a single endpoint. Respo...
Source: Acta Anaesthesiologica Taiwanica - August 27, 2015 Category: Anesthesiology Authors: Liou JY, Tsou MY, Ting CK Tags: Acta Anaesthesiol Taiwan Source Type: research
Effect of gabapentin pretreatment on the hemodynamic response to laryngoscopy and tracheal intubation in treated hypertensive patients.
CONCLUSION: Gabapentin 800 mg in a single or double dose was equally effective in attenuating the hypertensive response to laryngoscopy and tracheal intubation in treated hypertensive patients.
PMID: 26314902 [PubMed - as supplied by publisher] (Source: Acta Anaesthesiologica Taiwanica)
Source: Acta Anaesthesiologica Taiwanica - August 24, 2015 Category: Anesthesiology Authors: Bala I, Bharti N, Ramesh NP Tags: Acta Anaesthesiol Taiwan Source Type: research
Efficacy of transverse abdominis plane block in reduction of postoperation pain in laparoscopic cholecystectomy.
CONCLUSION: The present study demonstrated that bilateral TAP block with 0.5% bupivacaine reduces post laparoscopic cholecystectomy pain intensity and fentanyl request and prolongs time to the first analgesic request. Adding sufentanil to the block solution reduced neither pain intensity nor fentanyl further consumption.
PMID: 26282913 [PubMed - as supplied by publisher] (Source: Acta Anaesthesiologica Taiwanica)
Source: Acta Anaesthesiologica Taiwanica - August 14, 2015 Category: Anesthesiology Authors: Saliminia A, Azimaraghi O, Babayipour S, Ardavan K, Movafegh A Tags: Acta Anaesthesiol Taiwan Source Type: research
Pneumorrhachis as a result of epidural anesthesia.
PMID: 26282914 [PubMed - as supplied by publisher] (Source: Acta Anaesthesiologica Taiwanica)
Source: Acta Anaesthesiologica Taiwanica - August 14, 2015 Category: Anesthesiology Authors: Singh S, Thakur H Tags: Acta Anaesthesiol Taiwan Source Type: research
Anesthesia, surgical stress, and "long-term" outcomes.
Abstract
An increasing body of evidence shows that the choice of anesthetic can strongly influence more than simply the quality of anesthesia. Regional and general anesthesia have often been compared to ascertain whether one provides benefits through dampening the stress response or harms by accelerating cancer progression. Regional anesthesia offers considerable advantages, by suppressing cortisol and catecholamine levels and reducing muscle breakdown postoperatively. It also has less immunosuppressive effect and potentially reduces the proinflammatory cytokine response. As such, vital organ functions (e....
Source: Acta Anaesthesiologica Taiwanica - July 30, 2015 Category: Anesthesiology Authors: Iwasaki M, Edmondson M, Sakamoto A, Ma D Tags: Acta Anaesthesiol Taiwan Source Type: research
Vasopressin inhibits mitogen-activated protein kinases and activated protein-1 in macrophages.
CONCLUSION: Vasopressin inhibits MAPKs and AP-1 in endotoxin-activated macrophages.
PMID: 26210797 [PubMed - as supplied by publisher] (Source: Acta Anaesthesiologica Taiwanica)
Source: Acta Anaesthesiologica Taiwanica - July 22, 2015 Category: Anesthesiology Authors: Chen YL, Chang YY, Kao MC, Huang CJ Tags: Acta Anaesthesiol Taiwan Source Type: research
Does intravenous atropine affect stroke volume variation in man?
CONCLUSION: Administration of intravenous atropine did not change SVV, and we present this as a novel finding.
PMID: 26205325 [PubMed - as supplied by publisher] (Source: Acta Anaesthesiologica Taiwanica)
Source: Acta Anaesthesiologica Taiwanica - July 20, 2015 Category: Anesthesiology Authors: Wajima Z, Shiga T, Imanaga K Tags: Acta Anaesthesiol Taiwan Source Type: research
The unique role of transdermal buprenorphine in the global chronic pain epidemic.
Abstract
Pain is a global epidemic, exacerbated by barriers to access of opioid analgesics. Regulations about opioids attempt to protect public health from the risks of harmful use of opioids, diversion, and dependence. Transdermal buprenorphine is an effective opioid analgesic agent with unique properties that may make it particularly well suited for more widespread use. It is a versatile analgesic product with demonstrated safety and effectiveness in cancer and noncancer pain populations. Its pharmacological properties make it a first-line opioid analgesic for geriatric patients and patients with renal d...
Source: Acta Anaesthesiologica Taiwanica - July 20, 2015 Category: Anesthesiology Authors: Pergolizzi JV, Scholten W, Smith KJ, Leighton-Scott J, Willis JC, Henningfield JE Tags: Acta Anaesthesiol Taiwan Source Type: research
Grand mal seizure induced by low-dose fentanyl and lidocaine in a young child.
This report is on a rare complication likely caused by fentanyl or lidocaine, which suggests that these drugs should be used cautiously in children whose clinical epileptic activities have been verified or are strongly suspected.
PMID: 26108757 [PubMed - as supplied by publisher] (Source: Acta Anaesthesiologica Taiwanica)
Source: Acta Anaesthesiologica Taiwanica - June 21, 2015 Category: Anesthesiology Authors: Hsieh XX, Hsu YC, Cherng CH, Lin CC, Huang GS, Lin SL, Wu ZF, Yeh CC Tags: Acta Anaesthesiol Taiwan Source Type: research
Improving access to adequate pain management in Taiwan.
Abstract
There is a global crisis in access to pain management in the world. WHO estimates that 4.65 billion people live in countries where medical opioid consumption is near to zero. For 2010, WHO considered a per capita consumption of 216.7 mg morphine equivalents adequate, while Taiwan had a per capita consumption of 0.05 mg morphine equivalents in 2007. In Asia, the use of opioids is sensitive because of the Opium Wars in the 19th century and for this reason, the focus of controlled substances policies has been on the prevention of diversion and dependence. However, an optimal public health outcome r...
Source: Acta Anaesthesiologica Taiwanica - June 8, 2015 Category: Anesthesiology Authors: Scholten W Tags: Acta Anaesthesiol Taiwan Source Type: research
