Support for Small Business Innovation Research (SBIR) to Develop New Technologies for Development and Integration of Novel Components for Open and Closed Loop Hormone Replacement Platforms for T1D Therapy (R43/R44 Clinical Trial Not Allowed)
This Funding Opportunity Announcement (FOA) invites Small Business Innovation Research (SBIR) grant applications for funding to perform research leading to the development of new approaches to create devices/components with enhanced accuracy and less patient burden that will represent real advancements regarding safety and effectiveness of glucose control technologies and their integration into open and closed loop hormone replacement systems.RFA-DK-19-027 (Source: NIDDK Funding Opportunities)
Source: NIDDK Funding Opportunities - December 3, 2019 Category: Endocrinology Source Type: funding

The Physiology of the Weight Reduced State Data Coordinating Center (U24 Clinical Trial Not Allowed)
This Funding Opportunity Announcement (FOA) invites U24 cooperative agreement applications for a Data Coordination Center to participate in a clinical trial focused on elucidation of the physiological mechanisms underlying individual variability in maintenance of reduced weight over time. A companion FOA (RFA DK-19-017, The Physiology of the Weight Reduced State Clinical Trial Consortium (UG3/UH3 Clinical Trial Required) invites Clinical Centers (CC) to recruit and study participants before and after a behavioral/lifestyle weight loss intervention to determine the extent, durability and mechanisms for physiologic adaptatio...
Source: NIDDK Funding Opportunities - November 22, 2019 Category: Endocrinology Source Type: funding

The Physiology of the Weight Reduced State Clinical Trial Consortium (UG3/UH3 Clinical Trial Required)
Following intentional weight loss, physiological processes including altered appetite and decreased energy expenditure create a tendency toward regain of lost weight. This Funding Opportunity Announcement (FOA) invites UG3/UH3 cooperative agreement applications from multi-disciplinary teams that propose to conduct collaborative mechanistic clinical trials focused on elucidation of the physiological mechanisms underlying individual variability in maintenance of reduced weight over time. This FOA will not support studies with a goal to evaluate the efficacy of interventions for weight loss or maintenance of reduced weight. P...
Source: NIDDK Funding Opportunities - November 22, 2019 Category: Endocrinology Source Type: funding

Limited Competition: Competitive Supplement to the Coordinating Center for Type 1 Diabetes TrialNet (U01 Clinical Trial Required)
Type 1 diabetes (T1D) is a serious and burdensome chronic disease that usually onsets in childhood or early adulthood. Recent progress in clinical trials and understanding of T1D pathogenesis and mechanisms have created opportunities to delay the onset and progression of the disease. This supplement is intended to provide resources for the design and conduct of new intervention studies in individuals at early pre-clinical stages of T1D and in individuals with new-onset T1D through the T1D TrialNet network (TrialNet). This Funding Opportunity Announcement (FOA) invites an application from the Program Director/Principal Inve...
Source: NIDDK Funding Opportunities - November 14, 2019 Category: Endocrinology Source Type: funding

Exploratory Centers for Interdisciplinary Research in Benign Urology (P20 Clinical Trial Optional)
The purpose of this Funding Opportunity Announcement (FOA) is to seek applications for Exploratory Centers for Interdisciplinary Research in Benign Urology (P20). A major goal of this program is to build interdisciplinary research teams. The program seeks innovative, high-riskhigh-reward Research Projects that utilize integrative approaches to address questions relevant to benign genitourinary diseases or disorders bringing together investigators with complementary expertise. Studies involving human subjects or tissues and small, innovative, pilot and feasibility clinical studies are encouraged. The following expertise mus...
Source: NIDDK Funding Opportunities - November 12, 2019 Category: Endocrinology Source Type: funding

Limited Competition for the Closeout of the SEARCH for Diabetes in Youth Cohort Study (R01 Clinical Trial Not Allowed)
The purpose of this Funding Opportunity Announcement (FOA) is to complete the SEARCH for Diabetes in Youth Cohort Study. SEARCH has recruited a cohort of youth with diabetes who have been followed longitudinally. The purpose of this FOA is to complete data analyses and disseminate scientific findings regarding the evolution of diabetes-related complications, including mortality, and processes of care and quality of life.RFA-DK-19-507 (Source: NIDDK Funding Opportunities)
Source: NIDDK Funding Opportunities - November 8, 2019 Category: Endocrinology Source Type: funding

Notice of Special Interest: Small Business Development of Wearable Smart Devices for Continuous Monitoring of Circulating Nutrients, Metabolites and Hormones
The purpose of this Notice is to inform potential applicants of an area of special interest in developing tools for continuous monitoring of circulating or interstitial nutrients, metabolites or hormones relevant to diet and nutrition.Christopher J. Lynch, Ph.D. | NOT-DK-20-002 (Source: NIDDK Funding Opportunities)
Source: NIDDK Funding Opportunities - November 6, 2019 Category: Endocrinology Source Type: funding

Mechanisms Underlying the Contribution of Type 1 Diabetes Disease-associated Variants (R01 Clinical Trial Not Allowed)
This Funding Opportunity Announcement (FOA) encourages applications from integrative teams and individual investigators for large-scale complex multi-disciplinary Functional Genomics Projects (FGPs) to determine the contributions and mechanisms underlying the contribution of associated variants for type 1 diabetes (T1D). Genome-wide association studies (GWAS) and other genomic studies of T1D have found many variants that are statistically associated with disease risk or disease protection, but they have not clearly shown which variants in genomic elements cause these effects or how they result in differences in function. A...
Source: NIDDK Funding Opportunities - November 6, 2019 Category: Endocrinology Source Type: funding

Notice of Special Interest: Development of Swallowable Smart Pills or Devices for Precision Nutrition, Microbiome and Digestive Disease Applications
The purpose of this Notice is to inform potential applicants of an area of special interest in developing swallowable smart pills or devices to advance precision nutrition, microbiome and gastroenterological research.Christopher J. Lynch, Ph.D. | NOT-DK-20-001 (Source: NIDDK Funding Opportunities)
Source: NIDDK Funding Opportunities - November 1, 2019 Category: Endocrinology Source Type: funding

Support of Competitive Research (SCORE) Pilot Project Award (SC2 - Clinical Trial Not Allowed)
The SCORE Program is a developmental program designed to increase the research competitiveness of faculty and the research base at institutions with an explicitly stated historical mission and/or a demonstrated track record within the previous 10 years of training and graduating students from backgrounds underrepresented in biomedical research. Eligible institutions must award science degrees to undergraduate (B.S. or B.A.) and/or graduate students (M.S. or Ph.D.) and have received less than 6 million dollars per year of NIH R01 support (total costs) in each of the last 2 fiscal years.Lawrence Agodoa, M.D. | PAR-20-040 (So...
Source: NIDDK Funding Opportunities - October 24, 2019 Category: Endocrinology Source Type: funding

Support of Competitive Research (SCORE) Research Advancement Award (SC1 - Clinical Trial Not Allowed)
The SCORE Program is a developmental program designed to increase the research competitiveness of faculty and the research base at institutions with an explicitly stated historical mission and/or a demonstrated track record within the previous 10 years of training and graduating students from backgrounds underrepresented in biomedical research. Eligible institutions must award science degrees to undergraduate (B.S. or B.A.) and/or graduate students (M.S. or Ph.D.) and have received less than 6 million dollars per year of NIH R01 support (total costs) in each of the last 2 fiscal years.Lawrence Agodoa, M.D. | PAR-20-039 (So...
Source: NIDDK Funding Opportunities - October 24, 2019 Category: Endocrinology Source Type: funding

HIV-associated Non-Communicable Diseases Research at Low- and Middle-Income Country Institutions (R21 Clinical Trial Optional)
The goal of this -program is to support locally relevant research in critical areas of HIV-associated non-communicable diseases (NCDs) at Low- and Middle-Income Country (LMIC) Institutions, to enhance research capacity and build a network of researchers both within and across LMICs to address this critical burden. This initiative is expected to stimulate new research on the interplay between HIV and development of NCDs in persons living with HIV (PLWH), including exploratory studies to uncover the extent to which HIV infection influences the etiopathogenesis of the NCDs; and to identify and develop appropriate approaches f...
Source: NIDDK Funding Opportunities - October 18, 2019 Category: Endocrinology Source Type: funding

Notice of Special Interest (NOSI): Next-Generation Approaches to Renal Replacement Therapy Including Vascular Access
This NOSI aims to support the development of innovative approaches to renal replacement therapy and address critical accompanying challenges such as vascular access and fluid management during dialysis.Daniel Gossett, Ph.D. | NOT-DK-19-027 (Source: NIDDK Funding Opportunities)
Source: NIDDK Funding Opportunities - October 9, 2019 Category: Endocrinology Source Type: funding

HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 - Clinical Trial Not Allowed)
The purpose of this Funding Opportunity Announcement (FOA) aims to speed scientific solutions to stem the national opioid public health crisis by supporting the development of therapies and technologies directed at enhanced pain management through the Small Business Innovation Research (SBIR) program. This FOA is focused on applications directed at improving pain treatment, including the development of new non-addictive medications and devices and objective pain measurement. In addition, NIH is interested in new screening tools and models focused specifically on pain and development of pain therapies.RFA-NS-20-011 (Source:...
Source: NIDDK Funding Opportunities - October 4, 2019 Category: Endocrinology Source Type: funding

HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 - Clinical Trial Required)
The purpose of this Funding Opportunity Announcement (FOA) aims to speed scientific solutions to stem the national opioid public health crisis by supporting the development of therapies and technologies directed at enhanced pain management through the Small Business Innovation Research (SBIR) program. This FOA is focused on applications directed at improving pain treatment, including the development of new non-addictive medications and devices and objective pain measurement. In addition, NIH is interested in new screening tools and models focused specifically on pain and development of pain therapies.RFA-NS-20-010 (Source:...
Source: NIDDK Funding Opportunities - October 4, 2019 Category: Endocrinology Source Type: funding