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Scientists identify main component of brain repair after stroke
Looking at brain tissue from mice, monkeys and humans, scientists have found that a molecule known as growth and differentiation factor 10 (GDF10) is a key player in repair mechanisms following stroke. The findings suggest that GDF10 may be a potential therapy for recovery after stroke. The study, published in Nature Neuroscience, was supported by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health. (Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke)
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - October 28, 2015 Category: Neurology Source Type: news

An itch you just can’t scratch
Everyone knows the best way to suppress an itch is to scratch it, but for people who suffer from skin diseases like eczema, no amount of scratching can bring relief. Fortunately, help may be on the way. Scientists from the Buck Institute for Research on Aging and the University of California, Berkeley have identified a pair of proteins responsible for chronic itching. The study, published in Neuron and partially funded by the NIH’s National Institute of Neurological Disorders and Stroke (NINDS), may lead to treatments that can stop an itch at its source. (Source: NINDS Press Releases and News: National Institute of Neuro...
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - October 27, 2015 Category: Neurology Source Type: news

Study in mice shows how brain ignores distractions
In a study of mice, scientists discovered that a brain region called the thalamus may be critical for filtering out distractions. The study, published in Nature and partially funded by the National Institutes of Health, paves the way to understanding how defects in the thalamus might underlie symptoms seen in patients with autism, attention deficit hyperactivity disorder (ADHD), and schizophrenia. (Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke)
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - October 21, 2015 Category: Neurology Source Type: news

Nuclear transport problems linked to ALS and FTD
Three teams of scientists supported by the National Institutes of Health showed that a genetic mutation linked to some forms of amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD) may destroy neurons by disrupting the movement of materials in and out of the cell’s nucleus, or command center where most of its DNA is stored. (Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke)
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - October 16, 2015 Category: Neurology Source Type: news

NIH invests $85 million for BRAIN Initiative research
The National Institutes of Health announced its second wave of grants to support the goals of the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative, bringing the NIH investment to $85 million in fiscal year 2015. (Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke)
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - October 1, 2015 Category: Neurology Source Type: news

Dormant viral genes may awaken to cause ALS
Scientists at the National Institutes of Health (NIH) discovered that reactivation of ancient viral genes embedded in the human genome may cause the destruction of neurons in some forms of amyotrophic lateral sclerosis (ALS). (Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke)
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - September 30, 2015 Category: Neurology Source Type: news

Scientists uncover nuclear process in the brain that may affect disease
Every brain cell has a nucleus, or a central command station. Scientists have shown that the passage of molecules through the nucleus of a star-shaped cell, called an astrocyte, may play a critical role in health and disease. The study, published in the journal Nature Neuroscience, was partially funded by the National Institutes of Health (NIH). (Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke)
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - August 17, 2015 Category: Neurology Source Type: news

Neurons' broken machinery piles up in ALS
A healthy motor neuron needs to transport its damaged components from the nerve-muscle connection all the way back to the cell body in the spinal cord. If it cannot, the defective components pile up and the cell becomes sick and dies. (Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke)
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - August 12, 2015 Category: Neurology Source Type: news

PINK1 protein crucial for removing broken-down energy reactors
Cells are powered by tiny energy reactors called mitochondria. When damaged, they leak destructive molecules that can cause substantial harm and eventually kill brain cells. Scientists at the NIH’s National Institute of Neurological Disorders and Stroke (NINDS) showed that a protein called PINK1 that is implicated in Parkinson’s disease is critical for helping cells get rid of dysfunctional mitochondria. (Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke)
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - August 12, 2015 Category: Neurology Source Type: news

Scientists adopt new strategy to find Huntington’s disease therapies
Scientists searched the chromosomes of more than 4,000 Huntington’s disease patients and found that DNA repair genes may determine when the neurological symptoms begin. Partially funded by the National Institutes of Health, the results may provide a guide for discovering new treatments for Huntington’s disease and a roadmap for studying other neurological disorders. (Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke)
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - August 7, 2015 Category: Neurology Source Type: news

Crystal clear images uncover secrets of hormone receptors
Many hormones and neurotransmitters work by binding to receptors on a cell’s exterior surface. This activates receptors causing them to twist, turn and spark chemical reactions inside cells. NIH scientists used atomic level images to show how the neuropeptide hormone neurotensin might activate its receptors. Their description is the first of its kind for a neuropeptide-binding G protein-coupled receptor (GPCR), a class of receptors involved in a wide range of disorders and the target of many drugs. (Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke)
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - July 31, 2015 Category: Neurology Source Type: news

Futuristic brain probe allows for wireless control of neurons
A study showed that scientists can wirelessly control the path a mouse walks with just a press of a button. Researchers at the Washington University School of Medicine, St. Louis, and University of Illinois, Urbana-Champaign, created a remote controlled, next-generation tissue implant that allows neuroscientists to inject drugs and shine lights on neurons deep inside the brains of mice. (Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke)
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - July 16, 2015 Category: Neurology Source Type: news

Progesterone does not significantly improve outcome after traumatic brain injury
Results of a phase 3 randomized, placebo-controlled clinical trial suggest that progesterone may not significantly improve outcomes in patients who have suffered a moderate to severe traumatic brain injury. (Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke)
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - June 16, 2015 Category: Neurology Source Type: news

Normal neuronal firing may spark brain tumor growth
Using human brain tumor samples, scientists have discovered that normal patterns of nerve cell firing may enhance the growth of cancer cells. They also found that, neuroligin-3 (NLGN3), a gene known to be important for brain cell communication, may influence tumor growth and patient survival, making it a potential new target for therapy. The study, published in Cell, was partially funded by the National Institutes of Health (NIH). (Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke)
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - June 16, 2015 Category: Neurology Source Type: news

NIH Names Walter J. Koroshetz, M.D. Director of the National Institute of Neurological Disorders and Stroke
National Institutes of Health Director Francis S. Collins, M.D., Ph.D. announced today the selection of Walter J. Koroshetz, M.D., as the Director of the National Institute of Neurological Disorders and Stroke (NINDS). He has served as Acting Director of the NINDS since October, 2014. (Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke)
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - June 11, 2015 Category: Neurology Source Type: news