Teriflunomide effective for faster-advancing MS
NATIONAL HARBOR, MD. – The approved once-daily oral immunomodulator teriflunomide is effective in reducing relapse, and worsening of relapsing forms, of multiple sclerosis (RMS) in patients with... (Source: Clinical Neurology News)
Source: Clinical Neurology News - June 10, 2016 Category: Neurology Source Type: news

Temozolomide + RT boosts survival in elderly with glioblastoma
CHICAGO – Adding concomitant and adjuvant temozolomide to a shorter course of radiotherapy (RT) for elderly patients with glioblastoma improves progression-free survival, according to a phase III... (Source: Clinical Neurology News)
Source: Clinical Neurology News - June 10, 2016 Category: Neurology Source Type: news

Smoking causes worse outcome in MS
NATIONAL HARBOR, MD. – Follow-up of a cohort of patients in the United Kingdom has demonstrated associations between smoking and a higher risk of development of multiple sclerosis (MS), progression... (Source: Clinical Neurology News)
Source: Clinical Neurology News - June 9, 2016 Category: Neurology Source Type: news

Tandem beats single ASCT for childhood neuroblastoma
CHICAGO – More children treated for high-risk neuroblastoma who received a second autologous stem cell transplant in consolidation after induction chemotherapy were alive after 3 years compared with... (Source: Clinical Neurology News)
Source: Clinical Neurology News - June 9, 2016 Category: Neurology Source Type: news

LAA occlusion studied for stroke prevention in atrial fib with prior intracerebral hemorrhage
PARIS – Transcatheter left atrial appendage occlusion shows promise in providing a far better stroke prevention strategy than does standard medical management in patients with atrial fibrillation who... (Source: Clinical Neurology News)
Source: Clinical Neurology News - June 9, 2016 Category: Neurology Source Type: news

IL-2 adds only toxicity to neuroblastoma antibody tx
CHICAGO – Adding the cytokine IL-2 to front-line therapy with the anti-GD2 antibody ch14.18/CHO provided no additional survival benefit and only added to toxicity in the treatment of pediatric... (Source: Clinical Neurology News)
Source: Clinical Neurology News - June 8, 2016 Category: Neurology Source Type: news

TAVR cerebral protection device appears safe, effective
PARIS – The TriGuard neuroprotection device for use during transcatheter aortic valve replacement effectively prevented strokes while raising no safety concerns in a pooled analysis of three... (Source: Clinical Neurology News)
Source: Clinical Neurology News - June 7, 2016 Category: Neurology Source Type: news

MS imaging guidelines from North American group offer standardized protocols
NATIONAL HARBOR, MD. – Updated imaging protocols for patients with multiple sclerosis from a panel of North American neurology and radiology experts promise to improve the accuracy of diagnosis and... (Source: Clinical Neurology News)
Source: Clinical Neurology News - June 5, 2016 Category: Neurology Source Type: news

FDA is investigating Zecuity sumatriptan patch for reports of serious burns
The Food and Drug Administration is evaluating patient reports of serious burns and potential permanent scarring that have occurred with the use of the Zecuity patch (sumatriptan iontophoretic... (Source: Clinical Neurology News)
Source: Clinical Neurology News - June 2, 2016 Category: Neurology Source Type: news

Early results positive for treating high-grade gliomas with virus-based therapy
An investigational virus-based therapy was safely given to patients with high-grade or recurrent gliomas in a phase I study, improving survival for some, investigators report. <table... (Source: Clinical Neurology News)
Source: Clinical Neurology News - June 1, 2016 Category: Neurology Source Type: news

Zinbryta approved by FDA for relapsing forms of multiple sclerosis
Daclizumab (Zinbryta) has been approved as a patient-injected, once-monthly treatment for adults with relapsing forms of multiple sclerosis (MS), according to the Food and Drug Administration.... (Source: Clinical Neurology News)
Source: Clinical Neurology News - June 1, 2016 Category: Neurology Source Type: news

Thank you notes: Helpful on bad days
I get the occasional heartfelt thank you note from a patient. I also get hate mail, but fortunately the thank yous predominate. I still have all of them, going back to residency, in an old Nike box.... (Source: Clinical Neurology News)
Source: Clinical Neurology News - May 27, 2016 Category: Neurology Source Type: news

Probuphine implant predicted to ease buprenorphine maintenance
Probuphine, a subdermal buprenorphine implant <a href="http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm503719.htm?source=govdelivery&utm_medium=email&utm_source=govdelivery... (Source: Clinical Neurology News)
Source: Clinical Neurology News - May 27, 2016 Category: Neurology Source Type: news

Age, lower baseline ALC increase dimethyl fumarate lymphopenia risk
VANCOUVER – The risk of dimethyl fumarate lymphopenia – and perhaps progressive multifocal leukoencephalopathy – is greatest in patients 60 years or older and those with baseline absolute lymphocyte... (Source: Clinical Neurology News)
Source: Clinical Neurology News - May 26, 2016 Category: Neurology Source Type: news

Ocrelizumab bests interferon for relapsing MS at 2 years
VANCOUVER – Ocrelizumab, a B-cell depleting humanized monoclonal antibody being developed by Hoffman–La Roche, consistently outperformed interferon beta-1a (Rebif) for relapsing multiple sclerosis in... (Source: Clinical Neurology News)
Source: Clinical Neurology News - May 25, 2016 Category: Neurology Source Type: news