Drug targeting Huntington’s disease–causing protein undergoing clinical trial
A drug that was found to have no dose-limiting side effects in nonhuman primates is being evaluated in a clinical trial for its ability to reduce production of the protein that causes Huntington’s... (Source: Clinical Neurology News)
Source: Clinical Neurology News - February 26, 2016 Category: Neurology Source Type: news

Fingolimod improved gait impairment in small study
NEW ORLEANS – Treatment with fingolimod improved gait impairment in treatment-naive multiple sclerosis (MS) patients and those on a previous first-line therapy in a small, single-center... (Source: Clinical Neurology News)
Source: Clinical Neurology News - February 26, 2016 Category: Neurology Source Type: news

VIDEO: Novel tools measure disease progression in MS
NEW ORLEANS – The visual system is relevant and accessible for the study of multiple sclerosis and can aid in the measurement of neuronal and axonal injury. Capturing primary neuronal loss in the... (Source: Clinical Neurology News)
Source: Clinical Neurology News - February 25, 2016 Category: Neurology Source Type: news

Brief measure helpful for insomnia complaints
LAS VEGAS – For patients who present with complaints of insomnia, consider using the principles of the Brief Behavioral Treatment of Insomnia tool as your frontline approach. “It’s a pragmatic... (Source: Clinical Neurology News)
Source: Clinical Neurology News - February 25, 2016 Category: Neurology Source Type: news

VIDEO: Beware legal land mines when working with PAs, NPs
AUSTIN, TEX. – As use of mid-level providers grows, legal risks for practices also can rise. In this video interview at an American Health Lawyers Association conference, attorney <a... (Source: Clinical Neurology News)
Source: Clinical Neurology News - February 25, 2016 Category: Neurology Source Type: news

Positive headway reported for progressive multiple sclerosis
NEW ORLEANS – On top of the first success with an investigational pharmaceutical agent for primary progressive multiple sclerosis reported last year, the otherwise negative results from recent... (Source: Clinical Neurology News)
Source: Clinical Neurology News - February 25, 2016 Category: Neurology Source Type: news

VIDEO: Rapidly improving stroke patients still at risk for bad outcomes
LOS ANGELES – Stroke patients might seem to improve on their way to the hospital, but it’s hard to know if they really are. Investigators at State University of New York, Brooklyn, have taken a... (Source: Clinical Neurology News)
Source: Clinical Neurology News - February 25, 2016 Category: Neurology Source Type: news

VIDEO: MS stem cell therapy research progresses, including oligodendrocyte progenitor trial
NEW ORLEANS – Stem cell therapy for progressive multiple sclerosis is an intriguing and controversial topic, and the state of the related science was addressed during a session on “the treatment... (Source: Clinical Neurology News)
Source: Clinical Neurology News - February 24, 2016 Category: Neurology Source Type: news

Ocrelizumab subanalysis hints at better efficacy with active inflammatory lesions
NEW ORLEANS – The greatest effect of the investigational, B-cell–targeting humanized monoclonal antibody ocrelizumab in treating primary progressive multiple sclerosis (PPMS) may be in patients with... (Source: Clinical Neurology News)
Source: Clinical Neurology News - February 24, 2016 Category: Neurology Source Type: news

Long-term PPI use linked to increased risk of dementia
Long-term use of proton pump inhibitors was significantly associated with later diagnoses of dementia in adults aged 75 years and older in a prospective cohort study of more than 73,000 individuals.... (Source: Clinical Neurology News)
Source: Clinical Neurology News - February 24, 2016 Category: Neurology Source Type: news

AMA’s Stack ‘cautiously optimistic’ about MACRA implementation
WASHINGTON – Coming regulations to implement the MACRA legislation also could include sweeping reforms to meaningful use and quality reporting programs, said Dr. Steven J. Stack, president of the... (Source: Clinical Neurology News)
Source: Clinical Neurology News - February 24, 2016 Category: Neurology Source Type: news

Blood-borne biomarkers of MS relapse identified
NEW ORLEANS – Three potentially useful blood-based biomarkers of relapse and of the response to glatiramer acetate treatment have been identified in patients with relapsing-remitting multiple... (Source: Clinical Neurology News)
Source: Clinical Neurology News - February 24, 2016 Category: Neurology Source Type: news

Dr. Robert Califf confirmed as FDA commissioner
Dr. Robert M. Califf was confirmed as Commissioner of the Food and Drug Administration by an 89-4 vote of the full Senate on Feb. 24. Physician associations praised the Senate’s confirmation,... (Source: Clinical Neurology News)
Source: Clinical Neurology News - February 24, 2016 Category: Neurology Source Type: news

Treatment justified even for moderately advanced MS disability
NEW ORLEANS – Research from Australia shows that disability in multiple sclerosis (MS) is independent of past damage, even in people whose disease is moderately advanced, with further disease... (Source: Clinical Neurology News)
Source: Clinical Neurology News - February 24, 2016 Category: Neurology Source Type: news

Nuanced approach works best for potential ECT patients
Las Vegas – Electroconvulsive therapy is useful for many patients, particularly those with more severe depressive symptoms and more treatment resistance, according to Dr. Bruce J. Cohen. However, a... (Source: Clinical Neurology News)
Source: Clinical Neurology News - February 24, 2016 Category: Neurology Source Type: news