Siblings of children with ASDs more likely to have psychiatric disorders
While familial clustering of schizophrenia, bipolar disorder, and autism spectrum disorders (ASDs) is established, little is known about siblings of people with ASDs in particular. So researchers looked at the risk for psychiatric and neurodevelopmental disorders among full siblings of probands with ASDs. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - May 25, 2016 Category: Psychiatry Tags: What's New in Research Source Type: research

CDC urges behavior therapy first for children ages 2–5 with ADHD
Young children ages 2 to 5 with attention‐deficit hyperactivity disorder (ADHD) should receive behavior therapy as a first‐line treatment over medication, which can improve ADHD symptoms without the side effects, the Centers for Disease Control and Prevention (CDC) urged health care providers in a report. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - May 25, 2016 Category: Psychiatry Tags: ADHD Source Type: research

Experts: Baby's mother is the best treatment for NAS
The best treatment for neonatal abstinence syndrome (NAS) is the baby's mother. This isn't new news, but in a country in which some mothers are still sent to jail and many lose custody of their newborns simply because they were in doctor‐ordered treatment with methadone or buprenorphine, the message bears repeating. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - April 25, 2016 Category: Psychiatry Tags: Maternal Opioid Use Source Type: research

FDA allows metformin for patients with mild to moderate kidney impairment
The U.S. Food and Drug Administration (FDA) is requiring labeling changes regarding the recommendations for metformin‐containing medicines for diabetes to expand metformin's use in certain patients with reduced kidney function. The current labeling strongly recommends against use of metformin in some patients whose kidneys do not work normally. The FDA was asked to review numerous medical studies regarding the safety of metformin use in patients with mild to moderate impairment in kidney function, and to change the measure of kidney function in the metformin drug labeling that is used to determine whether a patient can r...
Source: The Brown University Child and Adolescent Psychopharmacology Update - April 24, 2016 Category: Psychiatry Tags: From the FDA Source Type: research

Research Roundup
Type 2 diabetes and antipsychotic use warrant care in prescribing Report: Exposure to legal marijuana contributes to lower perceived risk (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - April 24, 2016 Category: Psychiatry Tags: Research Roundup Source Type: research

Prior authorization for youth impedes timely inpatient care
Children in need of immediate psychiatric hospitalization are experiencing long wait times for admission due to prior authorization required by insurance companies. Researchers suggest the time could be better spent with the young patients. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - April 24, 2016 Category: Psychiatry Tags: What's New in Research Source Type: research

Can children's birth date play role in ADHD diagnoses?
A child's age at the time he or she enters school may have an impact on a diagnosis of attention‐deficit hyperactivity disorder (ADHD), according to researchers from Taiwan in a new study. Researchers note that some reports have indicated a prevalence of up to 15% of children in Western countries are diagnosed with ADHD. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - April 24, 2016 Category: Psychiatry Tags: What's New in Research Source Type: research

Data indicate growing problems from marijuana, but little treatment
Newly published data indicate that the prevalence of marijuana use disorders has been on the increase, based on comparisons that utilize the criteria for diagnosing the disorder in the previous version of the DSM. Other findings about this adversely affected population suggest that perhaps neither marijuana users nor the system of care that treats addictions are taking the problem seriously enough. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - April 24, 2016 Category: Psychiatry Tags: Substance Use Disorder Source Type: research

Risperidone associated with low iron stores in some patients
Iron deficiency results in cognitive deficits in rodents, which can be reversed with stimulants. In humans, iron deficiency causes behavioral and neuropsychological impairments, both with or without anemia. For children with attention‐deficit hyperactivity disorder (ADHD), low ferritin — a marker of body iron stores — has been associated with more severe symptoms and a poorer response to psychostimulants. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - March 29, 2016 Category: Psychiatry Tags: Low Iron Source Type: research

Meet the new FDA commissioner
Robert M. Califf, M.D., is the Food and Drug Administration's commissioner of food and drugs. As the top official of the FDA, Califf is committed to strengthening programs and policies that enable the agency to carry out its mission to protect and promote the public health. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - March 28, 2016 Category: Psychiatry Tags: From the FDA Source Type: research

Research Roundup
Animal study finds high cocaine doses cause ‘autophagy’ in brain cells Health officials call on FDA to put black‐box warnings on benzodiazepines and opioids Benzodiazepine OD deaths more than quadrupled from 1996 to 2013 (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - March 28, 2016 Category: Psychiatry Tags: Research Roundup Source Type: research

Being on medication complicates sober housing, an alternative for young people after inpatient
When young people go to residential treatment for substance use disorders (SUDs), they are frequently recommended to live in some kind of sober housing setting afterward, rather than returning home to their old temptations. However, if these young people are on buprenorphine — which is, along with methadone and naltrexone, an approved medication for the treatment of opioid use disorders — they may not be welcome in sober homes. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - March 28, 2016 Category: Psychiatry Tags: In the News Source Type: research

Study finds young adults misusing ADHD stimulant medications on the rise
The number of young adults misusing methylphenidates and dextroamphetamine‐amphetamine is increasing, along with a sharp increase in emergency department (ED) visits related to the medications, say researchers. Prescriptions for the stimulant have remained unchanged, they said. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - March 28, 2016 Category: Psychiatry Tags: What's New in Research Source Type: research

Pediatricians not inquiring enough about maternal mental health
Fewer than half of pediatricians inquire of and screen mothers of patients to identify maternal depression, suggesting a missed opportunity to identify depression and refer women to treatment, according to researchers. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - March 28, 2016 Category: Psychiatry Tags: What's New in Research Source Type: research

DMDD: Few teens have it, and perhaps it should be eliminated or modified
As clinicians get accustomed to a new diagnosis in Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM‐5) — disruptive mood dysregulation disorder (DMDD) — there are still questions about the utility and clinical picture of the children it is supposed to describe. However, a recent study shows that very few adolescents have it, and that it should be modified or perhaps eliminated in the next DSM. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - March 28, 2016 Category: Psychiatry Tags: DMDD Source Type: research