Quality of Life Is Poorer for Patients With Stroke Who Require an Interpreter [Brief Report]
Background and Purpose—In multicultural Australia, some patients with stroke cannot fully understand, or speak, English. Language barriers may reduce quality of care and consequent outcomes after stroke, yet little has been reported empirically.Methods—An observational study of patients with stroke or transient ischemic attack (2010–2015) captured from 45 hospitals participating in the Australian Stroke Clinical Registry. The use of interpreters in hospitals, which is routinely documented, was used as a proxy for severe language barriers. Health-Related Quality of Life was assessed using the EuroQoL-5 dimension-3 lev...
Source: Stroke - February 26, 2018 Category: Neurology Authors: Monique F. Kilkenny, Natasha A. Lannin, Craig S. Anderson, Helen M. Dewey, Joosup Kim, Karen Barclay-Moss, Chris Levi, Steven Faux, Kelvin Hill, Brenda Grabsch, Sandy Middleton, Amanda G. Thrift, Rohan Grimley, Geoffrey Donnan, Dominique A. Cadilhac Tags: Race and Ethnicity, Mortality/Survival, Quality and Outcomes, Ischemic Stroke, Transient Ischemic Attack (TIA) Brief Reports Source Type: research
Stroke Self-Management Support Improves Survivors’ Self-Efficacy and Outcome Expectation of Self-Management Behaviors [Brief Report]
This article reports on the effectiveness of a new nurse-led self-efficacy–based stroke self-management program.Methods—A randomized controlled trial of participants recruited from 3 acute stroke units was conducted. The intervention group received the 4-week stroke self-management program. The control group received usual care. All participants were assessed at baseline and 8 weeks after randomization. Data were analyzed using generalized estimating equations. Outcomes included self-efficacy, outcome expectation, and satisfaction with performance of self-management behaviors.Results—One hundred twenty-eight particip...
Source: Stroke - February 26, 2018 Category: Neurology Authors: Suzanne H.S. Lo, Anne M. Chang, Janita P.C. Chau Tags: Nursing, Rehabilitation, Health Services Brief Reports Source Type: research
Thrombus Neutrophil Extracellular Traps Content Impair tPA-Induced Thrombolysis in Acute Ischemic Stroke [Brief Report]
Conclusions—This study suggests that thrombus NETs content may be responsible for reperfusion resistance, including mechanical or pharmacological approaches with intravenous tPA, irrespectively of their etiology. The efficacy of a strategy involving an administration of DNAse 1 in addition to tPA should be explored in the setting of AIS.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT02907736. (Source: Stroke)
Source: Stroke - February 26, 2018 Category: Neurology Authors: Celina Ducroux, Lucas Di Meglio, Stephane Loyau, Sandrine Delbosc, William Boisseau, Catherine Deschildre, Malek Ben Maacha, Raphael Blanc, Hocine Redjem, Gabriele Ciccio, Stanislas Smajda, Robert Fahed, Jean-Baptiste Michel, Michel Piotin, Laurence Salom Tags: Inflammation, Pathophysiology, Vascular Biology, Ischemic Stroke Brief Reports Source Type: research
Outcome After Reperfusion Therapies in Patients With Large Baseline Diffusion-Weighted Imaging Stroke Lesions [Brief Report]
Conclusions—Stroke patients with DWI lesion >70 mL may benefit from reperfusion therapy, especially those with isolated M1 occlusion or ischemia restricted to the superficial middle cerebral artery territory. The benefit of treatment seems questionable for patients with carotid occlusion or lesion extending to the deep middle cerebral artery territory. (Source: Stroke)
Source: Stroke - February 26, 2018 Category: Neurology Authors: Vincent Gautheron, Yu Xie, Marie Tisserand, Helene Raoult, Sebastien Soize, Olivier Naggara, Romain Bourcier, Sebastien Richard, Francis Guillemin, Serge Bracard, Catherine Oppenheim Tags: Magnetic Resonance Imaging (MRI), Prognosis, Revascularization, Quality and Outcomes, Ischemic Stroke Brief Reports Source Type: research
Size of Ruptured Intracranial Aneurysms Is Decreasing [Brief Report]
Background and Purpose—Decrease in the incidence of subarachnoid hemorrhage over the past decades has been related to decreased smoking rates, especially among (Source: Stroke)
Source: Stroke - February 26, 2018 Category: Neurology Authors: Miikka Korja, Riku Kivisaari, Behnam Rezai Jahromi, Hanna Lehto Tags: Epidemiology, Cerebral Aneurysm, Cerebrovascular Disease/Stroke Brief Reports Source Type: research
Reduced Intravoxel Incoherent Motion Microvascular Perfusion Predicts Delayed Cerebral Ischemia and Vasospasm After Aneurysm Rupture [Brief Report]
Conclusions—Decreased IVIM perfusion fraction f and blood flow–related parameter fD* correlate with DCI and proximal artery vasospasm development after cerebral aneurysm rupture. (Source: Stroke)
Source: Stroke - February 26, 2018 Category: Neurology Authors: Jeremy J. Heit, Max Wintermark, Blake W. Martin, Guangming Zhu, Michael P. Marks, Greg Zaharchuk, Robert L. Dodd, Huy M. Do, Gary K. Steinberg, Maarten G. Lansberg, Gregory W. Albers, Christian Federau Tags: Magnetic Resonance Imaging (MRI), Cerebral Aneurysm, Intracranial Hemorrhage, Aneurysm Brief Reports Source Type: research
Comorbid Psychiatric Disease Is Associated With Lower Rates of Thrombolysis in Ischemic Stroke [Brief Report]
Background and Purpose—Intravenous thrombolysis (IVT) improves outcomes after acute ischemic stroke but is underused in certain patient populations. Mental illness is pervasive in the United States, and patients with comorbid psychiatric disease experience inequities in treatment for a range of conditions. We aimed to determine whether comorbid psychiatric disease is associated with differences in IVT use in acute ischemic stroke.Methods—Acute ischemic stroke admissions between 2007 and 2011 were identified in the Nationwide Inpatient Sample. Psychiatric disease was defined by International Classification of Diseases, ...
Source: Stroke - February 26, 2018 Category: Neurology Authors: Diana M. Bongiorno, Gail L. Daumit, Rebecca F. Gottesman, Roland Faigle Tags: Quality and Outcomes, Ischemic Stroke Brief Reports Source Type: research
Patients With Undetermined Stroke Have Increased Atrial Fibrosis [Brief Report]
Conclusions—The LA phenotype that was found in patients with undetermined cause supports the hypothesis that an atrial disease may be associated with stroke. (Source: Stroke)
Source: Stroke - February 26, 2018 Category: Neurology Authors: Ana Catarina Fonseca, Pedro Alves, Nuno Inacio, Joao Pedro Marto, Miguel Viana–Baptista, Teresa Pinho–e–Melo, Jose M. Ferro, Ana G. Almeida Tags: Magnetic Resonance Imaging (MRI), Ischemic Stroke, Embolism Brief Reports Source Type: research
Five-Year Mortality After Transient Ischemic Attack [Brief Report]
Background and Purpose—We aimed at providing estimates of mortality associated with cardiometabolic comorbidity and incident readmission from cardiometabolic as compared with noncardiometabolic conditions after a first transient ischemic attack.Methods—Between 2000 and 2015, patients hospitalized for a first transient ischemic attack were examined for cardiometabolic comorbidities (diabetes mellitus, coronary artery disease, heart failure, and atrial fibrillation), 5-year incident hospitalization, and time to death.Results—Of 251 patients with transient ischemic attack, 134 (53%) had at least 1 and 55 (22%) had at le...
Source: Stroke - February 26, 2018 Category: Neurology Authors: Mohammed Yousufuddin, Nathan Young, Lawrence Keenan, Tammy Olson, Jessica Shultz, Taylor Doyle, Eimad M. Ahmmad, Kogulavadanan Arumaithurai, Paul Takahashi, Mohammad Hassan Murad Tags: Transient Ischemic Attack (TIA) Brief Reports Source Type: research
Relationship Between Visceral Infarction and Ischemic Stroke Subtype [Brief Report]
Conclusions—The prevalence of visceral infarction differed significantly across ischemic stroke subtypes. Cardioembolic and cryptogenic strokes were associated with a higher prevalence of visceral infarcts than noncardioembolic strokes. (Source: Stroke)
Source: Stroke - February 26, 2018 Category: Neurology Authors: Caitlin Finn, Peter Hung, Praneil Patel, Ajay Gupta, Hooman Kamel Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke, Embolism Brief Reports Source Type: research
Neuroprotective Effects of MAGL (Monoacylglycerol Lipase) Inhibitors in Experimental Ischemic Stroke [Basic Sciences]
Conclusions—Our results suggest that MAGL may contribute to the pathophysiology of focal cerebral ischemia and is thus a promising therapeutic target for the treatment of ischemic stroke. (Source: Stroke)
Source: Stroke - February 26, 2018 Category: Neurology Authors: Sang-Ho Choi, Allison L. Arai, Yongshan Mou, Byeongteck Kang, Cecil Chern-Chyi Yen, John Hallenbeck, Afonso C. Silva Tags: Animal Models of Human Disease, Basic Science Research, Inflammation, Ischemic Stroke Original Contributions Source Type: research
Vagus Nerve Stimulation Enhances Stable Plasticity and Generalization of Stroke Recovery [Basic Sciences]
Conclusions—This study provides the first evidence that VNS paired with rehabilitative training after stroke (1) doubles long-lasting recovery on a complex task involving forelimb supination, (2) doubles recovery on a simple motor task that was not paired with VNS, and (3) enhances structural plasticity in motor networks. (Source: Stroke)
Source: Stroke - February 26, 2018 Category: Neurology Authors: Eric C. Meyers, Bleyda R. Solorzano, Justin James, Patrick D. Ganzer, Elaine S. Lai, Robert L. Rennaker II, Michael P. Kilgard, Seth A. Hays Tags: Animal Models of Human Disease, Rehabilitation, Ischemic Stroke Original Contributions Source Type: research
Acute or Delayed Systemic Administration of Human Amnion Epithelial Cells Improves Outcomes in Experimental Stroke [Basic Sciences]
Conclusions—Systemic poststroke administration of hAECs elicits marked neuroprotection and facilitates mechanisms of repair and recovery. (Source: Stroke)
Source: Stroke - February 26, 2018 Category: Neurology Authors: Megan A. Evans, Rebecca Lim, Hyun Ah Kim, Hannah X. Chu, Chantelle V. Gardiner-Mann, Kimberly W.E. Taylor, Christopher T. Chan, Vanessa H. Brait, Seyoung Lee, Quynh Nhu Dinh, Antony Vinh, Thanh G. Phan, Velandai K. Srikanth, Henry Ma, Thiruma V. Arumugam, Tags: Animal Models of Human Disease, Cell Therapy, Stem Cells, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research
Microvasospasms After Experimental Subarachnoid Hemorrhage Do Not Depend on Endothelin A Receptors [Basic Sciences]
Conclusions—Our results indicate that ETA receptors, which mediate large artery spasms after SAH, do not seem to play a role in the development of microarterial spasms, suggesting that posthemorrhagic spasms are mediated by distinct mechanisms in large and small cerebral vessels. Given that cerebral microvessel dysfunction is a key factor for outcome after SAH, further research into the mechanisms that underlie posthemorrhagic microvasospasms is urgently needed. (Source: Stroke)
Source: Stroke - February 26, 2018 Category: Neurology Authors: Hanhan Liu, Ari Dienel, Karsten Scholler, Susanne M. Schwarzmaier, Kathrin Nehrkorn, Nikolaus Plesnila, Nicole A. Terpolilli Tags: Basic Science Research, Mechanisms, Pathophysiology, Translational Studies, Cerebrovascular Disease/Stroke Original Contributions Source Type: research
Validating the TeleStroke Mimic Score [Clinical Sciences]
We report the area under the curve in receiver-operating characteristic curve analysis with 95% confidence interval for our previously derived TM score in which lower TM scores correspond with a higher likelihood of being a stroke mimic.Results—Based on final diagnosis at the end of the telestroke consultation, there were 630 of 1930 (32.6%) stroke mimics in the external validation cohort. All 6 variables included in the score were significantly different between patients with ischemic cerebrovascular disease versus stroke mimics. The TM score performed well (area under curve, 0.72; 95% confidence interval, 0.70–0.73; P (Source: Stroke)
Source: Stroke - February 26, 2018 Category: Neurology Authors: Syed F. Ali, Gordian J. Hubert, Jeffrey A. Switzer, Jennifer J. Majersik, Roland Backhaus, L. Wylie Shepard, Kishore Vedala, Lee H. Schwamm Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research
