Bronchial-pulmonary adenocarcinoma subtyping relates with different molecular pathways
Publication date: Available online 5 March 2015 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): Vítor Sousa , Bruno Bastos , Maria Silva , Ana Maria Alarcão , Lina Carvalho Lung cancer is one of the most common cancers in the world with a high mortality rate. We analyzed 45 surgical samples of the adenocarcinoma, 13 with lymph node metastasis. APC, BCL2, chromogranin A, CK 5/6/18 (LP34), CK20, CK7, cyclin D1, EGFR, ERCC1, HER2, Ki67, LRP, MRP, P53, RB and TTF1 expressions were evaluated by immunohistochemistry (IHC). Higher Ki67, APC, ERCC1 expressions and lower TTF1 expression were identif...
Source: Revista Portuguesa de Pneumologia - March 6, 2015 Category: Respiratory Medicine Source Type: research

Asthma control in the Portuguese National Asthma Survey
Conclusion More than half of the Portuguese patients presented controlled asthma and showed significantly better asthma-related quality of life. Almost 9 out of 10 patients with non-controlled disease have poor perception of their asthma control, which may hinder them from seeking better asthma control. (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - March 3, 2015 Category: Respiratory Medicine Source Type: research

Long-term impact of pre-operative physical rehabilitation protocol on the 6-min walk test of patients with adolescent idiopathic scoliosis: A randomized clinical trial
Conclusions Post-surgical recovery, evaluated by 6MWT, was significantly better in patients who underwent a 4-month pre-operative physical rehabilitation protocol. (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - February 26, 2015 Category: Respiratory Medicine Source Type: research

Diagnostic yield of sputum microbiological analysis in the diagnosis of pulmonary tuberculosis in a period of 10 years
Conclusions This study showed an incremental yield with more than one sputum sample. However, overall sensitivity remained low, suggesting a need for new diagnostic strategies and novel and better diagnostic tools. (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - February 26, 2015 Category: Respiratory Medicine Source Type: research

The value of cough peak flow measurements in the assessment of extubation or decannulation readiness
Publication date: Available online 13 February 2015 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): J.C. Winck , C. LeBlanc , J.L. Soto , F. Plano Insufficient cough strength has a major role in extubation and decannulation outcomes. Cough capacity can be easily evaluated by measuring flows during coughing. Values vary depending on whether cough flows are measured through the mouth or through a tracheostomy or endotracheal tube. It is important to standardize these measurements and start using them routinely in the extubation and decannulation processes. Values of cough peak flow >160L/...
Source: Revista Portuguesa de Pneumologia - February 20, 2015 Category: Respiratory Medicine Source Type: research

Respiratory parameters in elite athletes – does sport have an influence?
Conclusion The study suggests that specific type of training used in basketball, water polo or rowing could have potential for improving pulmonary function and rehabilitation. (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - February 20, 2015 Category: Respiratory Medicine Source Type: research

Pulmonary function, functional capacity and quality of life in adults with cystic fibrosis
Conclusion Adults with CF have reduced quality of life, which in part is associated with the severity of their lung function. (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - February 20, 2015 Category: Respiratory Medicine Source Type: research

Solitary fibrous tumors of the pleura: not always a benign entity
Publication date: Available online 18 February 2015 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): L.M. Nascimento , T. Gomes , A. Fernandes , A. Afonso (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - February 20, 2015 Category: Respiratory Medicine Source Type: research

Oxygen therapy: a clinical audit in an Internal Medicine Department
Publication date: Available online 18 February 2015 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): S. Nunes , J. Maia , J.P. Ferreira , J. Neves , I. Marques (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - February 20, 2015 Category: Respiratory Medicine Source Type: research

Combined intrapleural therapy in infectious pleural effusion
Publication date: Available online 18 February 2015 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): H. Dabó , L. Meira , I. Neves , A. Marinho , I. Gomes (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - February 20, 2015 Category: Respiratory Medicine Source Type: research

Tuberculosis screening and compliance rate with guidelines among Northern Portuguese Hospitals prescribers of anti-TNF therapy
Publication date: Available online 18 February 2015 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): B.A. Ferreira , S. Ribeiro , J. Meireles , A. Correia , R. Duarte (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - February 20, 2015 Category: Respiratory Medicine Source Type: research

Real-life efficacy and safety of omalizumab in Portuguese patients with persistent uncontrolled asthma
Conclusion The findings from the Portugal subpopulation of eXpeRience registry confirm that omalizumab add-on therapy is efficacious and well tolerated in the management of uncontrolled persistent allergic asthma. Another pertinent issue is the fact that the Portuguese subpopulation response is similar to the international population average of the study. (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - February 13, 2015 Category: Respiratory Medicine Source Type: research

Recurrent respiratory papillomatosis of the airway: The experience of an endoscopic unit
Conclusion Papillomatosis of the airway is a rare condition predisposing to malignant transformation. RRP tends to recur and repeated surgeries are needed to remove papillomatas. Endoscopic treatment is important for the removal of the papillomas that are not accessible via laryngoscopy (YAG Laser, cryotherapy, etc.) and for resistant moderate/severe cases of RPP because it allows intralesional administration of adjuvant therapy like cidofovir. (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - February 11, 2015 Category: Respiratory Medicine Source Type: research

Pancreatopleural fistula contributing to a large volume recurrent pleural effusion
Publication date: Available online 10 February 2015 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): J.T. Soares , J. Ressurreição , I. Marques , L. Batista , T. Pereira , M. Mendes (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - February 11, 2015 Category: Respiratory Medicine Source Type: research

Immune influence of pregnancy on human H7N9 infection: a case report
Conclusion These cases highlighted that the pregnant patient infected with H7N9 could induce an effective Th1 immune response equal to that of non-pregnant patients with H7N9 virus infection, although the pregnancy itself could lead to a Th2 deviation. These data suggested that pregnant patients could acquire a similar antiviral response for H7N9 infection versus non-pregnant patients. (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - February 11, 2015 Category: Respiratory Medicine Source Type: research