SER recommendations on the use of biological drugs in primary Sjögren's syndrome
ConclusionsRituximab is the biological agent of choice in severe extraglandular manifestations of pSS. Belimumab or abatacept may be useful in selected cases.ResumenObjetivoElaborar recomendaciones SER sobre el uso de agentes biológicos en el síndrome de Sjögren primario (SSp).MétodosSe identificaron preguntas clínicas de investigación relevantes sobre el uso de agentes biológicos en el SSp. Las preguntas clínicas se reformularon en 4 preguntas PICO. Se diseñó una estrategia de búsqueda y se realizó una revisión de la evidencia científica de estudios publicados hasta mayo de 2017. Se revisó sistemática...
Source: Reumatologia Clinica - November 16, 2019 Category: Rheumatology Source Type: research
Update of the Mexican College of Rheumatology guidelines for the pharmacological treatment of rheumatoid arthritis, 2018
ConclusionsThe updated recommendations of the Mexican College of Rheumatology on the pharmacological treatment of rheumatoid arthritis incorporate the best available information to be used in the Mexican health care system.ResumenLos avances terapéuticos en la artritis reumatoide obligan a revisión periódica de las guías de tratamiento.ObjetivoActualizar las guías del Colegio Mexicano de Reumatología del tratamiento farmacológico de la artritis reumatoide.MétodoParticiparon reumatólogos certificados de diferentes instituciones de salud y regiones del país. Se conformaron equipos de trabajo que revisaron las guía...
Source: Reumatologia Clinica - November 13, 2019 Category: Rheumatology Source Type: research
Aphthous stomatitis and laryngitis, another form of presentation of an IgG4-related disease?
We report the case of a 37-year-old woman who presented with severe dysphonia and recurrent painful aphthous ulcers, with histopathological findings at the level of the larynx that revealed a lymphoplasmacytic infiltrate and IgG4 positivity. In addition, extensive studies were performed to rule out other diseases. Thus the diagnosis was IgG4-related laryngitis, an exceptional finding in the literature.ResumenLa enfermedad relacionada con IgG4 (ER-IgG4) se caracteriza por un infiltrado linfoplasmocítico rico en células plasmáticas IgG4 positivas, fibrosis estoriforme y flebitis obliterativa. Se puede presentar como seudo...
Source: Reumatologia Clinica - November 10, 2019 Category: Rheumatology Source Type: research
Practical aspects of biological throughput levels and antidrug antibodies in rheumatoid arthritis and spondyloarthritis
ConclusionsEvidence-based algorithms and guidelines have been established to test drug levels and anti-drug antibodies in patients with RA and SpA, which can help clinical decision making.ResumenObjetivosEmitir recomendaciones sobre aspectos prácticos de la monitorización de los niveles de fármacos biológicos que puedan ser de utilidad para reumatólogos.MétodosSe realizó una revisión sistemática de la literatura de estudios en los que se determinaron niveles de fármaco y de anticuerpos antifármaco en pacientes con artritis reumatoide o espondiloartritis para estudiar si podían predecir diferentes desenlaces. Co...
Source: Reumatologia Clinica - November 1, 2019 Category: Rheumatology Source Type: research
Evaluation of the educational needs in Argentine patients with rheumatoid arthritis using the SpENAT questionnaire
ConclusionRA patients were very interested about knowing more about their disease. High functional impairment was associated with more ENs. Patients with high disease activity had higher EN levels in almost every domain. The rheumatologist was the main source of information for the patient with RA.ResumenIntroducciónEl Educational Needs Assessment Tool-versión española (SpENAT) es un cuestionario autorreportado que evalúa las necesidades educacionales (NEd) con el fin de dar información adaptada y centrada en el paciente con artritis reumatoide (AR). Comprende 39 preguntas agrupadas en 7 dominios: Manejo del dolor, Mo...
Source: Reumatologia Clinica - October 29, 2019 Category: Rheumatology Source Type: research
Quality health care in acute shoulder pain: What is the contribution of musculoskeletal ultrasound?
Publication date: Available online 28 October 2019Source: Reumatología Clínica (English Edition)Author(s): Carlos Guillén Astete, Sara Rodrigo González, Desiree Alfonso Pérez, Mónica Luque Alarcón, Roberto Penedo Alonso, María Jesús Estévez RuedaAbstractFor the purpose of assessing the impact of ultrasound in patients with acute shoulder pain, we conducted an analysis of quality health care indicators: need for reevaluation of the pain, rate of referral to specialized medicine and length of time in the emergency department. We reviewed the 1433 records of patients attended to between 2015 and 2016.Thirty days aft...
Source: Reumatologia Clinica - October 29, 2019 Category: Rheumatology Source Type: research
Cat Scratch Disease During Adalimumab Therapy: A Case Report
Publication date: September–October 2019Source: Reumatología Clínica (English Edition), Volume 15, Issue 5Author(s): Teresa Martins-Rocha, Cândida Abreu, Alexandra Bernardo, Miguel Bernardes, Joanne Lopes (Source: Reumatologia Clinica)
Source: Reumatologia Clinica - October 26, 2019 Category: Rheumatology Source Type: research
Anti C1q antibodies. A promising biomarker for cocaine-levamisole induced vasculitis
Publication date: September–October 2019Source: Reumatología Clínica (English Edition), Volume 15, Issue 5Author(s): José A. Gómez-Puerta, Carlos H. Muñoz, Adriana L. Vanegas-García, Tomás Urrego, Gloria Vásquez, Luis A. González (Source: Reumatologia Clinica)
Source: Reumatologia Clinica - October 26, 2019 Category: Rheumatology Source Type: research
Inter-observer agreement of standard joint count examination and disease global assessment in a cohort of Egyptian Rheumatoid Arthritis patients
ConclusionInter-observer reliability was better for TJCs than SJCs. Regarding SJCs agreement was better in large joints such as the knees compared to the small joints such as the MCPs. Disease global assessment may show discrepancy between patients and physicians.ResumenObjetivosEvaluar el acuerdo interobservador del recuento de articulaciones estándar entre el profesor experimentado y el candidato joven, y comparar la evaluación global de la enfermedad entre el profesor, el candidato joven y los pacientes.MétodosEste estudio incluyó a 100 pacientes con artritis reumatoide. Para todos los pacientes, la evaluación clí...
Source: Reumatologia Clinica - October 26, 2019 Category: Rheumatology Source Type: research
Validation of fragility fractures in primary care electronic medical records: A population-based study
ConclusionsMore than 4 in 5 major fractures recorded in SIDIAP are due to fragility (non-traumatic), with higher proportions for hip (92%) and vertebral (88%) fracture, and a lower proportion for fractures other than major ones. Our data support the validity of SIDIAP for the study of the epidemiology of osteoporotic fractures.ResumenObjetivosLa historia clínica informatizada utiliza una lista de códigos diagnósticos pre-especificados para identiticar fracturas, pero estos códigos no permiten distinguir entre fracturas traumáticas y fracturas por fragilidad. Se reporta la proporción de fracturas por fragilidad identi...
Source: Reumatologia Clinica - October 26, 2019 Category: Rheumatology Source Type: research
Subclinical synovitis and tenosynovitis by ultrasonography (US) 7 score in patients with rheumatoid arthritis treated with synthetic drugs, in clinical remission by DAS28
ConclusionsLow percentage of synovitis and tenosynovitis active were founded according to PD US by 7 score in RA patients under synthetic DMARDs during long remission. This score has benefit because evaluate tenosynovitis, another element of subclinical disease activity.ResumenObjetivoIdentificar la sinovitis y tenosinovitis activa mediante el uso de ultrasonido en un índice de 7 articulaciones (US7) en pacientes con artritis reumatoide (AR) en remisión clínica inducida por fármacos antirreumáticos modificadores de la enfermedad sintética (DMARD).MétodosSe trata de un estudio observacional multicéntrico, transversa...
Source: Reumatologia Clinica - October 26, 2019 Category: Rheumatology Source Type: research
Coexistence of sarcoidosis and adult onset Still disease
Publication date: September–October 2019Source: Reumatología Clínica (English Edition), Volume 15, Issue 5Author(s): Huseyin Semiz, Senol KobakAbstractSarcoidosis is a chronic, inflammatory disease with unknown cause characterized by non-caseating granuloma formations. It can be presented with bilateral hilar lymphadenopathy, skin lesions, eye involvement and locomotor system findings. Adult onset Still disease (AOSD) is a chronic inflammatory disease which presents with fever, arthritis and typical skin rashes. The disease is rare and can be misdiagnosed due to the absence of typical clinical and laboratory findings. ...
Source: Reumatologia Clinica - October 26, 2019 Category: Rheumatology Source Type: research
Retroperitoneal Fibrosis Associated With Immunoglobulin IgG4-related Disease in the Differential Diagnosis in Retroperitoneal Tumours. Case Report
Publication date: September–October 2019Source: Reumatología Clínica (English Edition), Volume 15, Issue 5Author(s): Gabriela Ruiz Mar, Óscar E. Cárdenas Serrano, Jorge Roldan García, Abraham Cañavera-Constantino, Víctor M. Menéndez Trejo, Óscar Chapa AzuelaAbstractThe patient was a 55-year-old woman with a 4-month history of pain in left flank that irradiated to the lumbar region. Computed tomography revealed a cystic tumor in the retroperitoneal region that compresses the ureter and left renal pelvis in contact with pancreatic body and tail. Surgery was performed and the definitive pathological report diagnose...
Source: Reumatologia Clinica - October 26, 2019 Category: Rheumatology Source Type: research
Late-onset Cogan's syndrome associated with large-vessel vasculitis
Publication date: September–October 2019Source: Reumatología Clínica (English Edition), Volume 15, Issue 5Author(s): Iván Cabezas-Rodríguez, Anahy Brandy-García, Carlos Rodríguez-Balsera, Paloma Rozas-Reyes, Belen Fernández-Llana, Luis Arboleya-RodríguezAbstractCogan's syndrome is a rare autoimmune disease that usually affects young Caucasian adults and is classically defined as the combination of nonsyphilitic interstitial keratitis and audiovestibular symptoms resembling Meniere's disease, both of them developed in an interval of less than two years. Nevertheless, cases with atypical ophthalmologic and audioves...
Source: Reumatologia Clinica - October 26, 2019 Category: Rheumatology Source Type: research
Tophaceous gout in the lumbar spine causing radiculopathy
We report the case of a 44-year-old patient with low back pain and radiculopathy. Radiographs revealed lytic spondylolisthesis in L5. Magnetic resonance imaging showed hypointense signal on T1 and a heterogeneous signal on T2 located in the L4-L5 interspinous space and in the left facet joint that invades left neuroforamen. The left knee ultrasound showed “double contour” of the medial femoral condyle. Decompressive laminectomy with arthrodesis at the level of L5-S1 was performed. The histological examination revealed amorphous material with a foreign body giant cell reaction.ResumenLos depósitos de tofos en columna l...
Source: Reumatologia Clinica - October 22, 2019 Category: Rheumatology Source Type: research
