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17-Hydroxyprogesterone caproate improves T cells and NK cells in response to placental ischemia; new mechanisms of action for an old drug
This study identifies new mechanisms whereby 17-OHPC improves outcomes in response to placental ischemia. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - December 3, 2019 Category: OBGYN Source Type: research

Preeclampsia exposed offspring have greater body mass index than non-exposed offspring during peripubertal life: A meta-analysis
ConclusionPreeclampsia poses risk of higher BMI and waist circumference especially to the offspring of older mothers. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - December 3, 2019 Category: OBGYN Source Type: research

Hyperferritinemia worsens the perinatal outcomes of conceptions of pregnancies with preeclampsia
ConclusionIn the presence of hyperferritinemia, preeclampsia patients were associated with a higher rate of unfavorable neonatal outcomes. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - November 29, 2019 Category: OBGYN Source Type: research

Editorial Board
Publication date: October 2019Source: Pregnancy Hypertension, Volume 18Author(s): (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - November 26, 2019 Category: OBGYN Source Type: research

Acknowledgement to Reviewers 2019
Publication date: October 2019Source: Pregnancy Hypertension, Volume 18Author(s): (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - November 26, 2019 Category: OBGYN Source Type: research

Corrigendum to “Preeclampsia postpartum: Impairment of cerebral autoregulation and reversible cerebral hyperperfusion” [Pregnancy Hypertens. 17 (2019) 121–126]
Publication date: Available online 14 November 2019Source: Pregnancy HypertensionAuthor(s): Wibke G. Janzarik, Jenny Jacob, Evi Katagis, Filiz Markfeld-Erol, Linda Sommerlade, Matthias Wuttke, Matthias Reinhard (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - November 14, 2019 Category: OBGYN Source Type: research

First-line antihypertensive treatment for severe hypertension in pregnancy: A systematic review and network meta-analysis
ConclusionsGiven the results of this systematic review and network meta-analysis, maternity care providers should feel comfortable initiating management of severe hypertension in pregnancy using oral nifedipine. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - November 1, 2019 Category: OBGYN Source Type: research

Vascular endothelial growth factor C/A 2578 gene polymorphism and umbilical artery Doppler in preeclamptic women
ConclusionWe concluded that VEGF 2578C/A polymorphism had no association with the occurrence of preeclampsia in studied groups, whereas there was a significant relationship among severe cases between CA and CC genotypes and pulsatility index of the umbilical artery. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - November 1, 2019 Category: OBGYN Source Type: research

The Reduced Uterine Perfusion Pressure (RUPP) rat model of preeclampsia exhibits impaired systolic function and global longitudinal strain during pregnancy
ConclusionsCardiac dysfunction and impaired strain are present in RUPP rats during pregnancy. These findings represent an animal model of PE that could be used to understand the mechanisms of cardiac dysfunction in this disease and ultimately, improve or prevent cardiac abnormalities in these patients. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - October 26, 2019 Category: OBGYN Source Type: research

Pregnancy outcomes in correlation with placental histopathology in subsequent pregnancies complicated by preeclampsia
ConclusionThe first event of preeclampsia is characterized by an earlier, more severe presentation, as well as a higher rate of MVM lesions, SGA, and adverse neonatal outcome, compared to preeclampsia in a subsequent pregnancy. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - October 22, 2019 Category: OBGYN Source Type: research

The association between maternal and foetal REN gene polymorphisms and preeclampsia/eclampsia: A hybrid design study
ConclusionsFindings from this study indicate that foetal rs5707 polymorphisms may play a significant role in PE/E development, especially among overweight or obese pregnant women in China. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - October 15, 2019 Category: OBGYN Source Type: research

Management of non-severe pregnancy hypertension – A summary of the CHIPS Trial (Control of Hypertension in Pregnancy Study) research publications
Publication date: October 2019Source: Pregnancy Hypertension, Volume 18Author(s): Laura A. Magee, Evelyne Rey, Elizabeth Asztalos, Eileen Hutton, Joel Singer, Michael Helewa, Terry Lee, Alexander G. Logan, Wessel Ganzevoort, Ross Welch, Jim G. Thornton, Peter von DadelszenAbstractThe international CHIPS Trial (Control of Hypertension In Pregnancy Study) enrolled 987 women with chronic (75%) or gestational (25%) hypertension. Pre-eclampsia developed in 48%; women remained on their allocated BP control and delivered an average of two weeks later. ‘Less tight’ control (target diastolic BP 100 mmHg) achieved BP that was ...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - October 15, 2019 Category: OBGYN Source Type: research

A randomised controlled trial of blood pressure self-monitoring in the management of hypertensive pregnancy. OPTIMUM-BP: A feasibility trial
ConclusionsThis is the first randomised investigation of BP self-monitoring for the management of pregnancy hypertension and indicates that a large RCT would be feasible. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - October 13, 2019 Category: OBGYN Source Type: research

Visit-to-visit blood pressure variability is associated with gestational hypertension and pre-eclampsia
ConclusionsVVV during pregnancy, especially SBP-CV, was independently associated with GH and PE. These results suggested that VVV could provide additional information to identify pregnant women at high risk of GH or PE. Further studies exploring prospective association between VVV, GH and PE are warranted. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - October 12, 2019 Category: OBGYN Source Type: research

Impact of gestational hypertension and preeclampsia on fetal gender: A large prospective cohort study in China
ConclusionsOur results support a slight but significant association between gestational hypertension or preeclampsia and decreased likelihood of male delivery. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - October 12, 2019 Category: OBGYN Source Type: research