The Predictive Value of Sonographic Placental Markers for Adverse Pregnancy Outcome in Women with Chronic Kidney Disease
Publication date: Available online 26 February 2020Source: Pregnancy HypertensionAuthor(s): Alexandra Moloney, Michelle Hladunewich, Eden Manly, Dini Hui, Stefania Ronzoni, John Kingdom, Vasilica Stratulat, Arthur Zaltz, Jon Barrett, Nir Melamed (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - February 26, 2020 Category: OBGYN Source Type: research

Postpartum Blood Pressure Trends Are Impacted by Race and BMI
Publication date: Available online 26 February 2020Source: Pregnancy HypertensionAuthor(s): Joana Lopes Perdigao, Adi Hirshberg, Nathanael Koelper, Sindhu K. Srinivas, Mary D. Sammel, Lisa D. Levine (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - February 26, 2020 Category: OBGYN Source Type: research

Association of the G994T and R92H genotypes of platelet-activating factor acetylhydrolase with risk of preeclampsia in Chinese women
Publication date: Available online 26 February 2020Source: Pregnancy HypertensionAuthor(s): Mi Zhou, Meng Chen, Huai Bai, Guo-Lin He, Qing-Qing Liu, Lin-Bo Guan, Xing-Hui Liu, Ping Fan (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - February 26, 2020 Category: OBGYN Source Type: research

Letter to the Editor regarding research integrity
Publication date: January 2020Source: Pregnancy Hypertension, Volume 19Author(s): George R. Saade, Ben W. Mol (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - February 22, 2020 Category: OBGYN Source Type: research

The role of hepatic sinusoidal obstruction in the pathogenesis of the hepatic involvement in HELLP syndrome: Exploring the literature
ConclusionThe available information supports the concept that the liver damage in HELLP and SOS results from sinusoidal ischemia, presumably resulting from partially overlapping pathophysiological mechanisms. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - February 22, 2020 Category: OBGYN Source Type: research

Home blood pressure monitoring in the antenatal and postpartum period: A systematic review meta-analysis
Publication date: January 2020Source: Pregnancy Hypertension, Volume 19Author(s): Erkan Kalafat, Can Benlioglu, Basky Thilaganathan, Asma KhalilAbstractRecent evidence suggests that home blood pressure monitoring (HBPM) is an effective way of managing women with hypertensive disorders of pregnancy (HDP) without increasing adverse outcomes. The aim of this systematic review and meta-analysis was to investigate the safety and efficacy of HBPM during pregnancy.Medline, EMBASE and the Cochrane library databases were searched electronically in November 2018. Studies were included from which data could be extracted on the pregna...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - February 22, 2020 Category: OBGYN Source Type: research

Uteroplacental acute atherosis in preeclamptic pregnancies: Rates and clinical outcomes differ by tissue collection methods
ConclusionsPlacental bed vacuum suction provides more spiral arteries and higher AA rate, suggesting underestimation of AA in conventional pathology samples of basal plate DB biopsies and DP. The association of AA with PE-related clinical parameters varies according to tissue collection method. Longitudinal studies could elucidate whether AA also identifies women with future premature cardiovascular risk. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - February 22, 2020 Category: OBGYN Source Type: research

Cardiovascular effects of severe late-onset preeclampsia are reversed within six months postpartum
ConclusionsCardiac effects after severe late-onset PE were small and transient. This indicates that left ventricular hypertrophy after severe late-onset PE may be a secondary physiologic response to increased peripheral resistance in PE. Vascular mechanisms rather than persistent cardiac hypertrophy postpartum may be the culprit for increased long-term cardiovascular risk after PE. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - February 22, 2020 Category: OBGYN Source Type: research

Resistance of aspirin during and after pregnancy: A longitudinal cohort study
ConclusionAspirin resistance was found in a considerable part of the participants. Considerable variation between participants, within participants over time and between the different devices was found. Prevalence of aspirin resistance during pregnancy differs from after pregnancy. More research on aspirin resistance and clinical obstetric outcome is needed. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - February 22, 2020 Category: OBGYN Source Type: research

Severe antepartum hypertension and associated peripartum morbidity among pregnant women in an urban tertiary care medical center
ConclusionsPatients with severe hypertension antepartum have higher associated maternal and fetal adverse events while treatment is often delayed. Further studies should evaluate the effects of adequate time to treatment for severe hypertension. Steps should also be taken to standardize identification and reporting of severe maternal morbidity. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - February 22, 2020 Category: OBGYN Source Type: research

Reply to letter regarding ‘Methyldopa versus Nifedipine or no medication for treatment of chronic hypertension during pregnancy’
Publication date: January 2020Source: Pregnancy Hypertension, Volume 19Author(s): Mohamed Rezk (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - February 22, 2020 Category: OBGYN Source Type: research

Angiogenesis biomarkers for the prediction of severe adverse outcomes in late-preterm preeclampsia
ConclusionsAngiogenic biomarkers are not useful to predict which late-preterm PE cases will develop severe features that require preterm delivery. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - February 22, 2020 Category: OBGYN Source Type: research

Are blood pressure level and variability related to pregnancy outcome? Analysis of control of hypertension in pregnancy study data
ConclusionsHigher BP is an adverse prognostic marker, regardless of target BP. While the association between higher BP variability and severe hypertension and pre-eclampsia may be related to higher BP at diagnosis, our results suggest a possible advantage of BP variability for the fetus, through undefined mechanisms.Tweetable abstractHigher blood pressure (BP) is associated with more adverse pregnancy outcomes, but higher BP variability may be good for the baby. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - February 22, 2020 Category: OBGYN Source Type: research

Acute kidney injury associated with preeclampsia or hemolysis, elevated liver enzymes, and low platelets syndrome
ConclusionHELLP syndrome, AKI and placental abruption or postpartum hemorrhage appear to be interrelated. AKI occurs more frequently in women with HELLP syndrome with or without associated postpartum hemorrhage and placental abruption. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - February 22, 2020 Category: OBGYN Source Type: research

The relationship of a Prothrombin G20210A mutation or a factor V Leiden mutation and on-aspirin platelet (re-)activity
ConclusionWe feel these data are suggestive of increased on-aspirin platelet (re-)activity, as measured by the PFA-200 and the VerifyNow, in non-pregnant carriers of a FII-mutation, but not in carriers of FVL-mutation. Interestingly, this increased on-aspirin platelet (re-)activity is present in spite of low sTxB2 levels. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - February 22, 2020 Category: OBGYN Source Type: research