Evaluation of Ocular Surface Disease in Asian Patients with Primary Angle Closure.
CONCLUSION: Ocular surface disease is common in PACG patients treated with topical pressure-lowering drugs. Topical pressure-lowering drugs caused significant OSD symptoms and signs except for tear production in PACG patients. Thorough evaluation of ocular surface disease is important to ensure appropriate treatment and intervention in PACG patients. PMID: 28400889 [PubMed - in process] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - April 14, 2017 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research

Comparison of Ethnic-specific Databases in Heidelberg Retina Tomography-3 to Discriminate Between Early Glaucoma and Normal Chinese Eyes.
CONCLUSION: Comparison of the 3 ethnic databases did not reveal significant differences to differentiate early glaucomatous from normal Chinese eyes. PMID: 28400890 [PubMed - in process] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - April 14, 2017 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research

Bilateral Choroidal Metastases from Endobronchial Carcinoid Treated with Somatostatin Analogues.
CONCLUSION: Endobronchial carcinoid tumors have an indolent nature and long-term follow-up is recommended for early detection of metastases. Although treatment with somatostatin analogues rarely induces complete tumor regression, tumor stabilization and prevention of symptoms related to hormone secretion is achieved. This well-tolerated systemic treatment provides a worthy alternative treatment for choroidal metastasis compared to classic radiotherapy without any risk of radiation or laser-related visual loss. PMID: 27843513 [PubMed - in process] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - November 17, 2016 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research

Characteristics of Sympathetic Ophthalmia in a Single International Center.
CONCLUSION: This report from a single center adds to the body of literature of sympathetic ophthalmia occurring in a specific population. Our data found a high proportion of patients with sympathetic ophthalmia after phacoemulsification. PMID: 27651849 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - September 23, 2016 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research

Long Term Clinical and Visual Outcomes of Retrofixated Iris Claw Lenses Implantation in Complicated Cases.
CONCLUSION: The visual outcome with RFIC lenses when combined with other intraocular procedures is mainly affected by the complexity of co-existing pathologies .The complications are more related to the combined procedures performed rather than RFIC lens implantation alone. This may still be acceptable when complication profile of other intraocular lenses is evaluated in similar challenging situations. PMID: 27347246 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - June 29, 2016 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research

Evaluation of a Public Child Eye Health Tertiary Facility for Pediatric Cataract in Southern Nigeria I: Visual Acuity Outcome.
CONCLUSION: Predictors of change in visual acuity in our study were; delayed presentation and pre-operative VA. Cataract surgery in children showed clinical benefit. PMID: 27347247 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - June 29, 2016 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research

Lithium-Induced Downbeat Nystagmus and Horizontal Gaze Palsy.
We report a case of lithium-induced downbeat nystagmus and horizontal gaze palsy in a 62-year-old woman who was treated for a bipolar affective disorder with lithium carbonate for one month. At presentation serum lithium was within therapeutic range. No alternative causes of the ocular motility disturbances were found, and the patient improved significantly as lithium carbonate was discontinued. PMID: 27347248 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - June 29, 2016 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research

Risk Factors for Primary Open Angle Glaucoma (POAG) Progression: A Study Ruled in Torino.
CONCLUSION: Results of this study confirm and enforce data coming from most recent studies: IOP remains the main risk factor for glaucoma assess and progression; age and familiarity are great risk factors as underlined in the last decades; female sex can be an important risk factors as emerged only in the last years; arterial hypertension should always be evaluated in timing of our clinic follow up. PMID: 27347249 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - June 29, 2016 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research

Ocular Tolerability of Preservative-Free Tafluprost and Latanoprost: in vitro and in vivo Comparative Study.
CONCLUSION: Comparing these two PF formulations in vitro and in vivo, it is considered that ocular tolerability of PF tafluprost is better than PF latanoprost. Taking into account the composition of these two PF PGA formulations, the solubilizing agent macrogolglycerol hydroxystearate 40 (MGHS40) contained in PF latanoprost formulation is a plausible cause for the negative effects. PMID: 27347250 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - June 29, 2016 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research

Efficacy and Safety of Switching Latanoprost Monotherapy to Bimatoprost Monotherapy or Combination of Brinzolamide and Latanoprost.
CONCLUSION: Bimatoprost monotherapy and brinzolamide adjunctive to latanoprost similarly reduced the IOP, with no additive adverse effects, compared with latanoprost monotherapy. PMID: 27073587 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - April 15, 2016 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research

Serial Intravitreal Bevacizumab Injections Slow the Progression of Radiation Maculopathy Following Iodine-125 Plaque Radiotherapy.
CONCLUSIONS: Intravitreal bevacizumab injection was effective in stabilizing visual acuity in patients with radiation maculopathy. Patients benefited most from injections administered every 90 days or sooner. Fluorescein angiography can help identify patients who will respond favorably to treatment. PMID: 27053973 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - April 9, 2016 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research

Morphologic Changes in Patient with Drusen and Drusenoid Pigment Epithelial Detachment after Intravitreal Ranibizumab for Choroidal Neovascular Membrane : A Case Report.
Authors: Kim S, Oh J, Kim K Abstract The authors present a case of morphologic changes of drusen and drusenoid pigment epithelial detachment (DPED) after treating choroidal neovascularization (CNV) using ranibizumab in age-related macular degeneration (AMD). A 71-year-old woman has noticed mild visual acuity deterioration in the right eye for several months. She was presented with some drusen and DPED associated with CNV. This patient was given intravitreal injection of 0.5 mg of ranibizumab five times at monthly intervals for treating CNV. DPED in the temporal and drusen in the superior to macula were dim...
Source: Open Ophthalmology Journal - March 26, 2016 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research

Ocular, Neurologic and Systemic Findings of the Cases with Optic Nerve Hypoplasia.
CONCLUSION: The vision of young children with ONH should be monitored at least annually, and any refractive errors should be treated. Neuroimaging of the brain and endocrinologic evaluation is necessary in all cases with ONH. PMID: 27014380 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - March 26, 2016 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research

The Effect of Intravitreal Azithromycin on the Albino Newborn Rabbit Retina.
CONCLUSION: In newborn rabbits, intravitreal azithromycin injection resulted in an apoptotic activity in the photoreceptor, bipolar and ganglion cells. Immunohistochemical analysis suggested that doses of 0.75 mg and 1.5 mg azithromycin, administered intravitreally might be toxic to the newborn rabbit retina. PMID: 27014381 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - March 26, 2016 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research

Retinopathy of Prematurity in Neonates and its Risk Factors: A Seven Year Study in Northern Iran.
CONCLUSION: The findings of current study demonstrate that the main risk factors of developing ROP in newborns are multiple gestation, low birth weight, oxygen therapy for more than five day. Therefore, the progression of ROP to blindness will be prevented by a high index of suspicion, suitable screening, prompt diagnosis, and early treatment. PMID: 27014382 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - March 26, 2016 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research