Editorial: Keratoconus - What We Do Not Know.
Authors: Gatzioufas Z, Hamada S, Lake D, Seitz B
PMID: 28932333 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - September 23, 2017 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Corneal Biomechanics in Ectatic Diseases: Refractive Surgery Implications.
CONCLUSIONS: The purpose of this review is to describe the current state of clinical evaluation of corneal biomechanics, focusing on the most recent advances of commercially available instruments and also on future developments, such as Brillouin microscopy.
PMID: 28932334 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - September 23, 2017 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Cataract Surgery in Patients with Keratoconus: Pearls and Pitfalls.
CONCLUSIONS: Determining the stage of KC, pre-operative patient counselling and the preferred method of refractive correction are all crucial to obtain successful postoperative outcomes and good patient satisfaction. The use of toric IOLs can achieve good results only in selected low-grade keratoconic eyes.
PMID: 28932335 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - September 23, 2017 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Genetics in Keratoconus - What is New?
CONCLUSION: The review focuses on current knowledge of these genetic risk factors associated with keratoconus.
PMID: 28932336 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - September 23, 2017 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Collagen Cross- Linking for Paediatric Keratoconus.
CONCLUSIONS: This article will present an update of the literature on the topic of CXL in this age group.
PMID: 28932337 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - September 23, 2017 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Recent Innovations in Collagen Corneal Cross-linking; a Mini Review.
CONCLUSION: This work highlights the recent advances of CXL, such as the role of oxygen, higher fluence and shorter irradiation times as well as the various clinical applications and updates of this method.
PMID: 28932338 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - September 23, 2017 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Penetrating Keratoplasty for Keratoconus - Excimer Versus Femtosecond Laser Trephination.
CONCLUSIONS: In contrast to the undisputed clinical advantages of excimer laser keratoplasty with orientation teeth/notches in keratoconus, the major disadvantage of femtosecond laser application is still the necessity of suction and applanation of the cone during trephination with intraoperative pitfalls and high postoperative astigmatism.
PMID: 28932339 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - September 23, 2017 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Contact Lenses for Keratoconus- Current Practice.
CONCLUSION: CLs seem to rehabilitate visual performance, diminishing the power of the cylinder and the high-order aberrations. The final choice of CLs is based on their special features, the subsequent corneal changes and the patient's needs.
PMID: 28932340 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - September 23, 2017 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Pathophysiology of Keratoconus: What Do We Know Today.
Authors: Soiberman U, Foster JW, Jun AS, Chakravarti S
Abstract
Keratoconus is a common corneal ectasia that leads to progressive visual impairment. Numerous studies have shown abnormal protein expression patterns in keratoconic corneas. However, the specific mechanisms causing this disease remain ambiguous. This review aims to provide an update on morphological studies of the keratoconic cornea, relate these early studies with current findings from proteomic, biochemical and cell culture studies and to postulate possible pathogenic pathways.
PMID: 28932341 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - September 23, 2017 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Combined Intravitreal Dexamethasone Implant And Micropulse Yellow Laser For Treatment Of Anti-VEGF Resistant Diabetic Macular Edema.
CONCLUSION: Intravitreal dexamethasone implant and micropulse laser are both effective and safe treatment options for anti-VEGF resistant diabetic macular edema.
PMID: 28839510 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - August 28, 2017 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
First Reported Case of Donor Related Candida Endophthalmitis after Descemet Membrane Endothelial Keratoplasty.
CONCLUSION: Candida interface keratitis and endophthalmitis can occur following DMEK and may be difficult to treat medically. Early removal of the donor material should be considered.
PMID: 28761565 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - August 2, 2017 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Many Faces of Renin-angiotensin System - Focus on Eye.
Authors: Holappa M, Vapaatalo H, Vaajanen A
Abstract
The renin-angiotensin system (RAS), that is known for its role in the regulation of blood pressure as well as in fluid and electrolyte homeostasis, comprises dozens of angiotensin peptides and peptidases and at least six receptors. Six central components constitute the two main axes of the RAS cascade. Angiotensin (1-7), an angiotensin converting enzyme 2 and Mas receptor axis (ACE2-Ang(1-7)-MasR) counterbalances the harmful effects of the angiotensin II, angiotensin converting enzyme 1 and angiotensin II type 1 receptor axis (ACE1-AngII-AT1R) Whereas sy...
Source: Open Ophthalmology Journal - August 2, 2017 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Using an Image Fusion Methodology to Improve Efficiency and Traceability of Posterior Pole Vessel Analysis by ROPtool.
CONCLUSION: Retinal image enhancement using robust mosaicing advances efforts to automate grading of posterior pole disease in ROP.
PMID: 28761567 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - August 2, 2017 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
The Effects of Ramadan Fasting on Anterior Segment Parameters, Visual Acuity and Intraocular Pressures of the Eye.
CONCLUSION: There is a need for more detailed and associated studies to understand better about the influence of Ramadan fast on various ocular parameters.
PMID: 28761568 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - August 2, 2017 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Efficacy and Safety of Switching from Prostaglandin Analog Therapy to Prostaglandin / Timolol Fixed Combination or Prostaglandin / Brimonidine Therapy.
CONCLUSION: Switching from a PG analogue to PG/timolol FCs or to PG with brimonidine was equally safe (systemically and topically) and effective in reducing IOP. Thus, PG with brimonidine might be appropriate medication in patients who cannot use PG/timolol FCs due to repiratory or circulatory disease.
PMID: 28761569 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - August 2, 2017 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
