Interventions to increase physical activity in children 0 –5 years old: a systematic review, meta‐analysis and realist synthesis
Obesity Reviews, EarlyView. (Source: Obesity Reviews)
Source: Obesity Reviews - September 26, 2018 Category: Eating Disorders & Weight Management Authors: J. A. Hnatiuk, H. E. Brown, K. L. Downing, T. Hinkley, J. Salmon, K. D. Hesketh Source Type: research

Built environment and cardio ‐metabolic health: systematic review and meta‐analysis of longitudinal studies
SummaryBuilt environment attributes may be related to cardio ‐metabolic diseases (e.g. type 2 diabetes, heart disease and stroke) and their risk factors, potentially by influencing residents' physical activity. However, existing literature reviews on the built environment and health for the most part focus on obesity as the outcome and rely on cross‐secti onal studies. This systematic review synthesized current evidence on longitudinal relationships between built environment attributes and cardio‐metabolic health outcomes among adults and on the potential mediating role of physical inactivity. By searching eight data...
Source: Obesity Reviews - September 25, 2018 Category: Eating Disorders & Weight Management Authors: M. Chandrabose, J. N. Rachele, L. Gunn, A. Kavanagh, N. Owen, G. Turrell, B. Giles ‐Corti, T. Sugiyama Tags: Obesity Comorbidity/Etiology Source Type: research

Oxytocin in metabolic homeostasis: implications for obesity and diabetes management
SummaryOxytocin was once understood solely as a neuropeptide with a central role in social bonding, reproduction, parturition, lactation and appetite regulation. Recent evidence indicates that oxytocin enhances glucose uptake and lipid utilization in adipose tissue and skeletal muscle, suggesting that dysfunction of the oxytocin system could underlie the pathogenesis of insulin resistance and dyslipidaemia. Murine studies revealed that deficiencies in oxytocin signalling and oxytocin receptor expression lead to obesity despite normal food intake, motor activity and increased leptin levels. In addition, plasma oxytocin conc...
Source: Obesity Reviews - September 25, 2018 Category: Eating Disorders & Weight Management Authors: C. Ding, M. K. ‐S. Leow, F. Magkos Tags: Obesity ‐Diabetes Management/Etiology and Pathophysiology Source Type: research

Built environment and cardio ‐metabolic health: systematic review and meta‐analysis of longitudinal studies
Obesity Reviews, EarlyView. (Source: Obesity Reviews)
Source: Obesity Reviews - September 25, 2018 Category: Eating Disorders & Weight Management Authors: M. Chandrabose, J. N. Rachele, L. Gunn, A. Kavanagh, N. Owen, G. Turrell, B. Giles ‐Corti, T. Sugiyama Source Type: research

Weight loss associated with sodium ‐glucose cotransporter‐2 inhibition: a review of evidence and underlying mechanisms
Obesity Reviews, EarlyView. (Source: Obesity Reviews)
Source: Obesity Reviews - September 25, 2018 Category: Eating Disorders & Weight Management Authors: P. C. Lee, S. Ganguly, S. ‐Y. Goh Source Type: research

Oxytocin in metabolic homeostasis: implications for obesity and diabetes management
Obesity Reviews, EarlyView. (Source: Obesity Reviews)
Source: Obesity Reviews - September 25, 2018 Category: Eating Disorders & Weight Management Authors: C. Ding, M. K. ‐S. Leow, F. Magkos Source Type: research

Adipose may actively delay progression of NAFLD by releasing tumor ‐suppressing, anti‐fibrotic miR‐122 into circulation
SummaryNonalcoholic fatty liver disease (NAFLD) is the most common liver pathology. Here we propose tissue ‐cooperative, homeostatic model of NAFLD. During early stages of NAFLD the intrahepatic production of miR‐122 falls, while the secretion of miRNA‐containing exosomes by adipose increases. Bloodstream carries exosome to the liver, where their miRNA cargo is released to regulate their intrahepat ic targets. When the deterioration of adipose catches up with the failing hepatic parenchyma, the external supply of liver‐supporting miRNAs gradually tapers off, leading to the fibrotic decompensation of the liver and a...
Source: Obesity Reviews - September 24, 2018 Category: Eating Disorders & Weight Management Authors: A. Baranova, D. Maltseva, A. Tonevitsky Tags: Obesity Comorbidity/Etiology and Pathophysiology Source Type: research

Adipose may actively delay progression of NAFLD by releasing tumor ‐suppressing, anti‐fibrotic miR‐122 into circulation
Obesity Reviews, EarlyView. (Source: Obesity Reviews)
Source: Obesity Reviews - September 24, 2018 Category: Eating Disorders & Weight Management Authors: A. Baranova, D. Maltseva, A. Tonevitsky Source Type: research

Overweight and obesity as major, modifiable risk factors for urinary incontinence in young to mid ‐aged women: a systematic review and meta‐analysis
Obesity Reviews, EarlyView. (Source: Obesity Reviews)
Source: Obesity Reviews - September 19, 2018 Category: Eating Disorders & Weight Management Authors: T. J.Lamerton , L.Torquati , W. J.Brown Source Type: research

Is metformin still the most efficacious first ‐line oral hypoglycaemic drug in treating type 2 diabetes? A network meta‐analysis of randomized controlled trials
Obesity Reviews, EarlyView. (Source: Obesity Reviews)
Source: Obesity Reviews - September 18, 2018 Category: Eating Disorders & Weight Management Authors: Y.Jia , Y.Lao , H.Zhu , N.Li , S. ‐W.Leung Source Type: research

Issue Information
Obesity Reviews,Volume 19, Issue 10, Page i-iv, October 2018. (Source: Obesity Reviews)
Source: Obesity Reviews - September 18, 2018 Category: Eating Disorders & Weight Management Source Type: research

Is metformin still the most efficacious first ‐line oral hypoglycaemic drug in treating type 2 diabetes? A network meta‐analysis of randomized controlled trials
ConclusionThis meta ‐analysis showed that repaglinide and metformin would be the most efficacious oral drugs for first‐line monotherapy of T2DM. (Source: Obesity Reviews)
Source: Obesity Reviews - September 17, 2018 Category: Eating Disorders & Weight Management Authors: Y. Jia, Y. Lao, H. Zhu, N. Li, S. ‐W. Leung Tags: Obesity Comorbidity/Treatment Source Type: research

Continuous cardiometabolic risk score definitions in early childhood: a scoping review
Obesity Reviews, EarlyView. (Source: Obesity Reviews)
Source: Obesity Reviews - September 17, 2018 Category: Eating Disorders & Weight Management Authors: M.Kamel , B. T.Smith , G.Wahi , S.Carsley , C. S.Birken , L. N.Anderson Source Type: research

Low ‐carbohydrate diets for overweight and obesity: a systematic review of the systematic reviews
Obesity Reviews, EarlyView. (Source: Obesity Reviews)
Source: Obesity Reviews - September 7, 2018 Category: Eating Disorders & Weight Management Authors: C.Churuangsuk , M.Kherouf , E.Combet , M.Lean Source Type: research