Causes and mechanisms of adipocyte enlargement and adipose expansion
Summary
Adipose tissue plays a significant role in whole body energy homeostasis. Obesity‐associated diabetes, fatty liver and metabolic syndrome are closely linked to adipose stress and dysfunction. Genetic predisposition, overeating and physical inactivity influence the expansion of adipose tissues. Under conditions of constant energy surplus, adipocytes become hypertrophic and adipose tissues undergo hyperplasia so as to increase their lipid storage capacity, thereby keeping circulating blood glucose and fatty acids below toxic levels. Nonetheless, adipocytes have a saturation point where they lose capacity to store m...
Source: Obesity Reviews - December 15, 2017 Category: Eating Disorders & Weight Management Authors: F. Haczeyni, K. S. Bell ‐Anderson, G. C. Farrell Tags: Etiology and Pathophysiology Source Type: research
The obesity supine death syndrome (OSDS)
Summary
The obesity supine death syndrome refers to a catastrophic cascade of cardiorespiratory complications resulting from the supine positioning of a morbidly obese subject which can ultimately lead to death. It was first described in 1977 in two massively obese patients who were forced to lie down for medical procedures. But surprisingly, despite the current worldwide epidemic of obesity, very few cases have been reported yet. It can be assumed that the syndrome is poorly recognized in clinical practice and may participate in the high rate of unexplained death in morbidly obese patients. Based on the previously publish...
Source: Obesity Reviews - December 14, 2017 Category: Eating Disorders & Weight Management Authors: M. Lemyze, A. Guiot, J. Mallat, D. Thevenin Tags: Obesity/Etiology and Pathophysiology Source Type: research
The obesity supine death syndrome (OSDS)
Obesity Reviews,Volume 19, Issue 4, Page 550-556, April 2018. (Source: Obesity Reviews)
Source: Obesity Reviews - December 13, 2017 Category: Eating Disorders & Weight Management Source Type: research
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Obesity Reviews,Volume 19, Issue 4, Page 550-556, April 2018. (Source: Obesity Reviews)
Source: Obesity Reviews - December 13, 2017 Category: Eating Disorders & Weight Management Source Type: research
Response to “actual body weight or perceived body, comments on ‘childhood obesity and school absenteeism: a systematic review and meta‐analysis’ ”
(Source: Obesity Reviews)
Source: Obesity Reviews - December 13, 2017 Category: Eating Disorders & Weight Management Authors: R. An, Y. Yang Tags: Letter to the Editor Source Type: research
