Encoding of danger by parabrachial CGRP neurons
almiter
Animals must respond to various threats to survive. Neurons that express calcitonin gene-related peptide in the parabrachial nucleus (CGRPPBN neurons) relay sensory signals that contribute to satiation and pain-induced fear behaviour, but it is unclear how they encode these distinct processes. Here, by (Source: Nature)
Source: Nature - March 21, 2018 Category: Research Authors: Carlos A. Campos Anna J. Bowen Carolyn W. Roman Richard D. Palmiter Tags: Article Source Type: research
De novo mutations in regulatory elements in neurodevelopmental disorders
thew E. Hurles
We previously estimated that 42% of patients with severe developmental disorders carry pathogenic de novo mutations in coding sequences. The role of de novo mutations in regulatory elements affecting genes associated with developmental disorders, or other genes, has been essentially unexplored. We identified (Source: Nature)
Source: Nature - March 21, 2018 Category: Research Authors: Patrick J. Short Jeremy F. McRae Giuseppe Gallone Alejandro Sifrim Hyejung Won Daniel H. Geschwind Caroline F. Wright Helen V. Firth David R. FitzPatrick Jeffrey C. Barrett Matthew E. Hurles Tags: Article Source Type: research
Erratum: The Beaker phenomenon and the genomic transformation of northwest Europe
Nature 555, 7697 (2018). doi:10.1038/nature26164
Author: Iñigo Olalde, Selina Brace, Morten E. Allentoft, Ian Armit, Kristian Kristiansen, Thomas Booth, Nadin Rohland, Swapan Mallick, Anna Szécsényi-Nagy, Alissa Mittnik, Eveline Altena, Mark Lipson, Iosif Lazaridis, Thomas K. Harper, Nick Patterson, Nasreen Broomandkhoshbacht, Yoan Diekmann, Zuzana Faltyskova, Daniel Fernandes, Matthew Ferry, Eadaoin Harney, Peter de Knijff, Megan Michel, Jonas Oppenheimer, Kristin Stewardson, Alistair Barclay, Kurt Werner Alt, Corina Liesau, Patricia Ríos, Concepción Blasco, Jorge Vega Miguel, Roberto Menduiña...
Source: Nature - March 21, 2018 Category: Research Authors: I ñigo Olalde Selina Brace Morten E. Allentoft Ian Armit Kristian Kristiansen Thomas Booth Nadin Rohland Swapan Mallick Anna Sz écsényi-Nagy Alissa Mittnik Eveline Altena Mark Lipson Iosif Lazaridis Thomas K. Harper Nick Patterson Nasreen Broomandkhosh Tags: Erratum Source Type: research
Erratum: Skin microbiota –host interactions
Erratum: Skin microbiota–host interactions
Nature 555, 7697 (2018). doi:10.1038/nature25994
Author: Y. Erin Chen, Michael A. Fischbach & Yasmine Belkaid
Nature553, 427–436 (2018); doi:10.1038/nature25177Owing to a technical error, authors Y. Erin Chen and Michael A. Fischbach were both listed as corresponding authors instead of authors Michael A. Fischbach and Yasmine Belkaid in the HTML version of (Source: Nature)
Source: Nature - March 21, 2018 Category: Research Authors: Y. Erin Chen Michael A. Fischbach Yasmine Belkaid Tags: Erratum Source Type: research
Corrigendum: Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification
Nature 555, 7697 (2018). doi:10.1038/nature25991
Author: Sven Reischauer, Oliver A. Stone, Alethia Villasenor, Neil Chi, Suk-Won Jin, Marcel Martin, Miler T. Lee, Nana Fukuda, Michele Marass, Alec Witty, Ian Fiddes, Taiyi Kuo, Won-Suk Chung, Sherveen Salek, Robert Lerrigo, Jessica Alsiö, Shujun Luo, Dominika Tworus, Sruthy M. Augustine, Sophie Mucenieks, Björn Nystedt, Antonio J. Giraldez, Gary P. Schroth, Olov Andersson & Didier Y. R. Stainier
Nature535, 294–298 (2016); doi:10.1038/nature18614In the Author Information section of this Letter, LT571435 from the SRA was provided as the acc...
Source: Nature - March 21, 2018 Category: Research Authors: Sven Reischauer Oliver A. Stone Alethia Villasenor Neil Chi Suk-Won Jin Marcel Martin Miler T. Lee Nana Fukuda Michele Marass Alec Witty Ian Fiddes Taiyi Kuo Won-Suk Chung Sherveen Salek Robert Lerrigo Jessica Alsi ö Shujun Luo Dominika Tworus Sruthy M. Tags: Corrigendum Source Type: research
Isotopic evolution of the protoplanetary disk and the building blocks of Earth and the Moon
nandes
Nucleosynthetic isotope variability among Solar System objects is often used to probe the genetic relationship between meteorite groups and the rocky planets (Mercury, Venus, Earth and Mars), which, in turn, may provide insights into the building blocks of the Earth–Moon system. Using this approach, it has been inferred that no primitive meteorite matches the terrestrial composition and the protoplanetary disk material from which Earth and the Moon accreted is therefore largely unconstrained. This conclusion, however, is based on the assumption that the observed nucleosynthetic variability of inner-Solar-Syst...
Source: Nature - March 21, 2018 Category: Research Authors: Martin Schiller Martin Bizzarro Vera Assis Fernandes Tags: Letter Source Type: research
A lithium –oxygen battery with a long cycle life in an air-like atmosphere
A lithium–oxygen battery with a long cycle life in an air-like atmosphere
Nature 555, 7697 (2018). doi:10.1038/nature25984
Authors: Mohammad Asadi, Baharak Sayahpour, Pedram Abbasi, Anh T. Ngo, Klas Karis, Jacob R. Jokisaari, Cong Liu, Badri Narayanan, Marc Gerard, Poya Yasaei, Xuan Hu, Arijita Mukherjee, Kah Chun Lau, Rajeev S. Assary, Fatemeh Khalili-Araghi, Robert F. Klie, Larry A. Curtiss & Amin Salehi-Khojin
Lithium–air batteries are considered to be a potential alternative to lithium-ion batteries for transportation applications, owing to their high theoretical specific energy. So f...
Source: Nature - March 21, 2018 Category: Research Authors: Mohammad Asadi Baharak Sayahpour Pedram Abbasi Anh T. Ngo Klas Karis Jacob R. Jokisaari Cong Liu Badri Narayanan Marc Gerard Poya Yasaei Xuan Hu Arijita Mukherjee Kah Chun Lau Rajeev S. Assary Fatemeh Khalili-Araghi Robert F. Klie Larry A. Curtiss Amin Sa Tags: Letter Source Type: research
Maximizing and stabilizing luminescence from halide perovskites with potassium passivation
Caterina Ducati, Richard H. Friend & Samuel D. Stranks
Metal halide perovskites are of great interest for various high-performance optoelectronic applications. The ability to tune the perovskite bandgap continuously by modifying the chemical composition opens up applications for perovskites as coloured emitters, in building-integrated photovoltaics, and as components of tandem photovoltaics to increase the power conversion efficiency. Nevertheless, performance is limited by non-radiative losses, with luminescence yields in state-of-the-art perovskite solar cells still far from 100 per cent under standard solar il...
Source: Nature - March 21, 2018 Category: Research Authors: Mojtaba Abdi-Jalebi Zahra Andaji-Garmaroudi Stefania Cacovich Camille Stavrakas Bertrand Philippe Johannes M. Richter Mejd Alsari Edward P. Booker Eline M. Hutter Andrew J. Pearson Samuele Lilliu Tom J. Savenije H åkan Rensmo Giorgio Divitini Caterina Du Tags: Letter Source Type: research
Continuous-wave room-temperature diamond maser
. M. Kay
The maser—the microwave progenitor of the optical laser—has been confined to relative obscurity owing to its reliance on cryogenic refrigeration and high-vacuum systems. Despite this, it has found application in deep-space communications and radio astronomy owing to its unparalleled performance as a low-noise amplifier and oscillator. The recent demonstration of a room-temperature solid-state maser that utilizes polarized electron populations within the triplet states of photo-excited pentacene molecules in a p-terphenyl host paves the way for a new class of maser. However, p-terphenyl has poor thermal an...
Source: Nature - March 21, 2018 Category: Research Authors: Jonathan D. Breeze Enrico Salvadori Juna Sathian Neil McN. Alford Christopher W. M. Kay Tags: Letter Source Type: research
Image reconstruction by domain-transform manifold learning
S. Rosen
Image reconstruction is essential for imaging applications across the physical and life sciences, including optical and radar systems, magnetic resonance imaging, X-ray computed tomography, positron emission tomography, ultrasound imaging and radio astronomy. During image acquisition, the sensor encodes an intermediate representation of an object in the sensor domain, which is subsequently reconstructed into an image by an inversion of the encoding function. Image reconstruction is challenging because analytic knowledge of the exact inverse transform may not exist a priori, especially in the presence of senso...
Source: Nature - March 21, 2018 Category: Research Authors: Bo Zhu Jeremiah Z. Liu Stephen F. Cauley Bruce R. Rosen Matthew S. Rosen Tags: Letter Source Type: research
van Berlo et al. reply
. Molkentin
REPLYING TO C.Vicinanzaet al. Nature55510.1038/nature25771 (2018)The accompanying Comment by Vicinanza et al. does not agree with our previous study regarding the utility of c-Kitpos (also known as Kitpos) cells (Source: Nature)
Source: Nature - March 21, 2018 Category: Research Authors: Jop H. van Berlo Onur Kanisicak Marjorie Maillet Ronald J. Vagnozzi Jason Karch Suh-Chin J. Lin Ryan C. Middleton Eduardo Marb án Jeffery D. Molkentin Tags: Brief Communication Arising Source Type: research
Kitcre knock-in mice fail to fate-map cardiac stem
cells
Kitcre knock-in mice fail to fate-map cardiac stem
cells
Nature 555, 7697 (2018). doi:10.1038/nature25771
Authors: Carla Vicinanza, Iolanda Aquila, Eleonora Cianflone, Mariangela Scalise, Fabiola Marino, Teresa Mancuso, Francesca Fumagalli, Emilia Dora Giovannone, Francesca Cristiano, Enrico Iaccino, Pina Marotta, Annalaura Torella, Roberto Latini, Valter Agosti, Pierangelo Veltri, Konrad Urbanek, Andrea M. Isidori, Dieter Saur, Ciro Indolfi, Bernardo Nadal-Ginard & Daniele Torella
ARISING FROM J. H.van Berloet al. Nature509, 337–341 (2014); doi:10.1038/nature13309In a cell fate-mappi...
Source: Nature - March 21, 2018 Category: Research Authors: Carla Vicinanza Iolanda Aquila Eleonora Cianflone Mariangela Scalise Fabiola Marino Teresa Mancuso Francesca Fumagalli Emilia Dora Giovannone Francesca Cristiano Enrico Iaccino Pina Marotta Annalaura Torella Roberto Latini Valter Agosti Pierangelo Veltri Tags: Brief Communication Arising Source Type: research
Timing of oceans on Mars from shoreline deformation
ingway
Widespread evidence points to the existence of an ancient Martian ocean. Most compelling are the putative ancient shorelines in the northern plains. However, these shorelines fail to follow an equipotential surface, and this has been used to challenge the notion that they formed via an early ocean and hence to question the existence of such an ocean. The shorelines’ deviation from a constant elevation can be explained by true polar wander occurring after the formation of Tharsis, a volcanic province that dominates the gravity and topography of Mars. However, surface loading from the oceans can drive polar wan...
Source: Nature - March 19, 2018 Category: Research Authors: Robert I. Citron Michael Manga Douglas J. Hemingway Tags: Letter Source Type: research
Massive Dirac fermions in a ferromagnetic kagome metal
ph G. Checkelsky
The kagome lattice is a two-dimensional network of corner-sharing triangles that is known to host exotic quantum magnetic states. Theoretical work has predicted that kagome lattices may also host Dirac electronic states that could lead to topological and Chern insulating phases, but these states have so far not been detected in experiments. Here we study the d-electron kagome metal Fe3Sn2, which is designed to support bulk massive Dirac fermions in the presence of ferromagnetic order. We observe a temperature-independent intrinsic anomalous Hall conductivity that persists above room temperature, which...
Source: Nature - March 19, 2018 Category: Research Authors: Linda Ye Mingu Kang Junwei Liu Felix von Cube Christina R. Wicker Takehito Suzuki Chris Jozwiak Aaron Bostwick Eli Rotenberg David C. Bell Liang Fu Riccardo Comin Joseph G. Checkelsky Tags: Letter Source Type: research
Extensive impact of non-antibiotic drugs on human gut bacteria
Athanasios Typas
A few commonly used non-antibiotic drugs have recently been associated with changes in gut microbiome composition, but the extent of this phenomenon is unknown. Here, we screened more than 1,000 marketed drugs against 40 representative gut bacterial strains, and found that 24% of the drugs (Source: Nature)
Source: Nature - March 19, 2018 Category: Research Authors: Lisa Maier Mihaela Pruteanu Michael Kuhn Georg Zeller Anja Telzerow Exene Erin Anderson Ana Rita Brochado Keith Conrad Fernandez Hitomi Dose Hirotada Mori Kiran Raosaheb Patil Peer Bork Athanasios Typas Tags: Article Source Type: research
