Neutrophil-Lymphocyte Ratio as a marker for Disability and Activity in Multiple Sclerosis
Publication date: Available online 28 March 2021Source: Multiple Sclerosis and Related DisordersAuthor(s): Rasha M. Fahmi, Bothina M. Ramadan, Hanan Salah, Ahmed F. Elsaid, Nahed Shehta (Source: Multiple Sclerosis and Related Disorders)
Source: Multiple Sclerosis and Related Disorders - March 29, 2021 Category: Neurology Source Type: research

Effects on gait and balance of home-based active video game interventions in persons with multiple sclerosis: a systematic review
Publication date: Available online 28 March 2021Source: Multiple Sclerosis and Related DisordersAuthor(s): Marion Dalmazane, Matthieu Gallou-Guyot, Maxence Compagnat, Laurent Magy, Alexis Montcuquet, Jean-Christophe Daviet, Anaick Perrochon (Source: Multiple Sclerosis and Related Disorders)
Source: Multiple Sclerosis and Related Disorders - March 28, 2021 Category: Neurology Source Type: research

Atypical inflammatory demyelinating syndrome with central and peripheral nerve involvement
Publication date: Available online 26 March 2021Source: Multiple Sclerosis and Related DisordersAuthor(s): Mena Farag, Naomi Sibtain, James Burge, Vinay Chaudhry, Eli Silber (Source: Multiple Sclerosis and Related Disorders)
Source: Multiple Sclerosis and Related Disorders - March 27, 2021 Category: Neurology Source Type: research

COVID-19 in patients with multiple sclerosis treated with cladribine tablets: An update
Publication date: Available online 27 March 2021Source: Multiple Sclerosis and Related DisordersAuthor(s): Dominic Jack, Doris Damian, Axel Nolting, Andrew Galazka (Source: Multiple Sclerosis and Related Disorders)
Source: Multiple Sclerosis and Related Disorders - March 27, 2021 Category: Neurology Source Type: research

Lung cancer risk in patients with multiple sclerosis: a Mendelian randomization analysis
Publication date: Available online 27 March 2021Source: Multiple Sclerosis and Related DisordersAuthor(s): Fan Ge, Zhenyu Huo, Caichen Li, Runchen Wang, Rui Wang, Yeling Liu, Jiana Chen, Yi Lu, Yaokai Wen, Yu Jiang, Haoxin Peng, Xiangrong Wu, Hengrui Liang, Jianxing He, Wenhua Liang (Source: Multiple Sclerosis and Related Disorders)
Source: Multiple Sclerosis and Related Disorders - March 27, 2021 Category: Neurology Source Type: research

Managing multiple sclerosis in the Covid19 era: a review of the literature and consensus report from a panel of experts in Saudi Arabia
Publication date: Available online 25 March 2021Source: Multiple Sclerosis and Related DisordersAuthor(s): Mohammed Al Jumah, Ahmad Abulaban, Hani Aggad, Reem Al Bunyan, Mona AlKhawajah, Yaser Al Malik, Mousa Almejally, Hind Alnajashi, Foziah Alshamrani, Saeed Bohlega, Edward J Cupler, Ahmed El Boghdady, Seraj Makkawi, Shireen Qureshi, Sahar Shami (Source: Multiple Sclerosis and Related Disorders)
Source: Multiple Sclerosis and Related Disorders - March 26, 2021 Category: Neurology Source Type: research

Reactivation of SARS-CoV-2 after Rituximab in a Patient with Multiple Sclerosis
Publication date: Available online 25 March 2021Source: Multiple Sclerosis and Related DisordersAuthor(s): Gauruv Bose, Kristin Galetta (Source: Multiple Sclerosis and Related Disorders)
Source: Multiple Sclerosis and Related Disorders - March 26, 2021 Category: Neurology Source Type: research

Middle-Age People with Multiple Sclerosis Demonstrate Similar Mobility Characteristics to Neurotypical Older Adults
Publication date: Available online 25 March 2021Source: Multiple Sclerosis and Related DisordersAuthor(s): Clayton W. Swanson, Sutton B. Richmond, Benjamin E. Sharp, Brett W. Fling (Source: Multiple Sclerosis and Related Disorders)
Source: Multiple Sclerosis and Related Disorders - March 26, 2021 Category: Neurology Source Type: research

Microstructural and functional brain abnormalities in multiple sclerosis predicted by osteopontin and neurofilament light
Publication date: Available online 24 March 2021Source: Multiple Sclerosis and Related DisordersAuthor(s): Gergely Orsi, Tamas Cseh, Zsofia Hayden, Gabor Perlaki, Szilvia Anett Nagy, Omar Giyab, Dorte Aalund Olsen, Jonna Skov Madsen, Timea Berki, Zsolt Illes (Source: Multiple Sclerosis and Related Disorders)
Source: Multiple Sclerosis and Related Disorders - March 25, 2021 Category: Neurology Source Type: research

Recurrence of disease activity after fingolimod discontinuation in older patients previously stable on treatment.: All patients with FTY withdrawal(n=128)Age (y) at disease onset (mean, SD)32.4, 8.9Sex, F/M (n)94/34Positive OCB (%)95.6Prior treatment (n, %)Treatment naiveFirst lineNTZOther 2d line56/128, 43.8 %59/128, 46.1 %11/128, 8.6 %2/128, 1.6 %Disease activity prior to FTY initiation Highly active patients (n, %)26/128, 20.3 %Relapses (mean, SD) 1, 0.9EDSS (median, range)2, 1-6.5No of new T2 lesions (mean, SD)4.7, 10.2No of Gd enhancing lesions (mean, SD)1.7, 5.6NEDA-3 status on FTY treatment (n, %)73/128, 57 %Age (y) at FTY discontinuation (mean, SD)41.6, 11Treatment duration (months) (mean, SD)40.3, 25.3Wash out period (days) (mean, SD)59.5, 44.1Age at fingolimod discontinuationYounger patients(n=52)Older patients(n=21) P valueAge (y) at disease onset (mean, SD)31.1, 741.1, 8.4<0.001Age (y) at FTY discontinuation(mean, SD)38.4, 7.756.8, 5<0.001Prior treatment (n, %)Treatment naiveFirst linePrevious NTZCladribine25/52, 58.124/52, 46.22/52, 3.81/52, 1.94/21, 1914/21, 66.71/21, 4.81/21, 4.80.119Disease activity prior to FTY initiation(mean, SD)RelapsesEDSS (median, range)No of new T2 lesionsNo of Gd enhancing lesions0.9, 11.5, 1-6.53.5, 71, 2.30.5, 0.72, 1.5-6.51.9, 3.20.5, 1.20.1010.2170.2080.226Treatment duration (m), (mean, SD)37.6, 29.646.8, 20.20.131Wash-out period (days) (mean, SD)90.8, 6767.7, 29.20.138Disease activity after FTY discontinuation (mean, SD)RelapsesEDSS 0.3, 0.61,5, 0-80.1, 0.32.0, 1-6.50.0690.051No of new T2 lesionsNo of Gd enhancing lesions3.5, 8.62.8, 8.50.6, 1.80.4, 1.40.0710.101DMT relay (n, %)NoneIFNDMFTRFNTZAnti-CD2032/52, 61.53/52, 5.83/52, 5.89/52, 17.31/52, 1.94/52, 7.74/21, 1905/21, 23.89/21, 42.903/21,14.30.013
Publication date: Available online 21 March 2021Source: Multiple Sclerosis and Related DisordersAuthor(s): Vasiliki Pantazou, Caroline Pot, Renaud Du Pasquier, Géraldine Le Goff, Marie Théaudin (Source: Multiple Sclerosis and Related Disorders)
Source: Multiple Sclerosis and Related Disorders - March 22, 2021 Category: Neurology Source Type: research

COVID-19 and the Risk of Relapse in Multiple Sclerosis Patients: A Fight with No Bystander Effect?
Publication date: Available online 20 March 2021Source: Multiple Sclerosis and Related DisordersAuthor(s): Masoud Etemadifar, Nahad Sedaghat, Ali Aghababaee, Parisa K Kargaran, Mohammad Reza Maracy, Mazdak Ganjalikhani-Hakemi, Milad Rayani, Amir Parsa Abhari, Reza Khorvash, Mehri Salari, Hosein Nouri (Source: Multiple Sclerosis and Related Disorders)
Source: Multiple Sclerosis and Related Disorders - March 21, 2021 Category: Neurology Source Type: research

Spinal cord involvement in LHON requires pathophysiological clarification
Publication date: Available online 21 March 2021Source: Multiple Sclerosis and Related DisordersAuthor(s): j Finsterer (Source: Multiple Sclerosis and Related Disorders)
Source: Multiple Sclerosis and Related Disorders - March 21, 2021 Category: Neurology Source Type: research

Restless Legs Syndrome in Multiple Sclerosis: risk factors and effect on sleep quality – a case-control study
Publication date: Available online 21 March 2021Source: Multiple Sclerosis and Related DisordersAuthor(s): Tobias Monschein, Christian Schestak, Cornelia Schillerwein-Kral, Fritz Leutmezer, Thomas Berger, Gabriel Bsteh, Stefan Seidel (Source: Multiple Sclerosis and Related Disorders)
Source: Multiple Sclerosis and Related Disorders - March 21, 2021 Category: Neurology Source Type: research

Obesity is associated with the Optic Neuritis severity in Male patients with Multiple Sclerosis
Publication date: Available online 21 March 2021Source: Multiple Sclerosis and Related DisordersAuthor(s): Duong T. Chu, Mattia Rosso, Cindy T. Gonzalez, Shrishti Saxena, Brian C. Healy, Howard L. Weiner, Tanuja Chitnis (Source: Multiple Sclerosis and Related Disorders)
Source: Multiple Sclerosis and Related Disorders - March 21, 2021 Category: Neurology Source Type: research

COVID-19 and emerging spinal cord complications: A systematic review
Publication date: Available online 21 March 2021Source: Multiple Sclerosis and Related DisordersAuthor(s): Ritwick Mondal, Shramana Deb, Gourav Shome, Upasana Ganguly, Durjoy Lahiri, Julián Benito-Leon (Source: Multiple Sclerosis and Related Disorders)
Source: Multiple Sclerosis and Related Disorders - March 21, 2021 Category: Neurology Source Type: research