Commentary On “Results of γ-Knife Radiosurgery of Brain Arteriovenous Malformations” (Liščá et al., This Issue)
(Source: Journal of Radiosurgery)
Source: Journal of Radiosurgery - June 1, 2000 Category: Radiology Source Type: research
Permanent I Interstitial Radiation Therapy in the Treatment of Non-GBM High-Grade Gliomas
This study evaluates prognostic factors influencing survival outcomes for 50 patients with permanent125 iodine-125 implants in the primary treatment of non-GBM high-grade gliomas. Stereotactic treatment planning aimed to encompass the contrast-enhancing rim of the tumor visualized by CT, with an initial dose rate of 0.05 Gy/hour with 125I, delivering 100 Gy at 1 year and 103.68 Gy at infinity. Survival was evaluated using the Kaplan–Meier method for unvariate analysis and the Cox regressional method for multivariate analysis. In addition to the implant, 31 patients received external radiation therapy (5000 to 6000 cGy) b...
Source: Journal of Radiosurgery - June 1, 2000 Category: Radiology Source Type: research
A Study and Automatic Solution for Multishot Treatment Planning for the γ-Knife
Abstract
It is recognized that multiple-shot radiosurgery using the Leksell Gamma Knife (LGK) can result in larger penumbra dose and less target dose homogeneity compared with a single shot treatment. In addition, the number of shots used increases significantly with increasing volume, which makes planning and optimization time consuming and complex. Although such complexity may not affect the accuracy of treatment delivery itself, it is difficult to assess the dosimetrical merits of a given plan. To deal with this complicated process, we have studied shot-related effects and target shape as separate is...
Source: Journal of Radiosurgery - June 1, 2000 Category: Radiology Source Type: research
Editorial About the Committee on Publication Ethics (COPE)
(Source: Journal of Radiosurgery)
Source: Journal of Radiosurgery - June 1, 2000 Category: Radiology Source Type: research
Results of γ-Knife Radiosurgery of Brain Arteriovenous Malformations
Abstract
Between 1992 and 1996 γ-knife radiosurgery was performed on 192 patients with the diagnosis of brain intracerebral arteriovenous malformations (AVM) at Na Homolce Hospital, Prague. The largest diameter of the nidus ranged between 0.6–5.4 cm, median 2.2 cm. The nidus volume ranged 0.15–28.6 cm2, median 3.9 cm2. Thus far, the angiographic evaluation after radiosurgery was performed in 162 patients. The treatment result reference was defined as follows: the interval with a lower limit represented by the percentage of the complete obliteration in the whole group of patients and the upper limit...
Source: Journal of Radiosurgery - June 1, 2000 Category: Radiology Source Type: research
The Use of Radiochromic Film in Treatment Verification of Proton Radiosurgery
Abstract
This paper describes the use of a MD-55 radiochromic film to measure proton doses and dose distributions in a homogeneous lucite phantom. Radiosurgery dose distributions were measured for the plateau and for the Bragg peak techniques with narrow proton beams. Measured distributions were compared to the dose distributions calculated with a 3-D image-based treatment planning system developed at Loma Linda University Medical Center, California and modified to accommodate to treatment delivery apparatus used at the Institute of Theoretical and Experimental Physics, Moscow, Russia. The results of th...
Source: Journal of Radiosurgery - June 1, 2000 Category: Radiology Source Type: research
Poor-Prognosis Patients with Cancer Metastatic to Brain: Implications for Stereotactic Radiosurgery
Abstract
The risk of brain recurrence after whole-brain radiotherapy for metastatic disease has been infrequently reported, but quoted to be as high as 50%. These values are in the context of autopsy series or clinical trials and thus may not represent experience in routine clinical practice. This retrospective analysis was undertaken: (1) to confirm recursive analysis-based prognostic factors contributing to survival; and (2) to investigate efficacy of Gamma Knife Stereotactic Radiosurgery (GKSRS) in the poorest prognosis population. The records of 85 unselected, consecutive patients receiving whole-br...
Source: Journal of Radiosurgery - June 1, 2000 Category: Radiology Source Type: research
Commentary On “Results of γ-Knife Radiosurgery of Brain Arteriovenous Malformations” (Liščá et al., This Issue)
(Source: Journal of Radiosurgery)
Source: Journal of Radiosurgery - June 1, 2000 Category: Radiology Source Type: research
Case Report: Intracerebral Hemorrhage After γ-Knife Surgery for Metastatic Brain Tumor
AbstractThe authors report a case of a 69-year-old man with metastatic brain tumors who died of spontaneous intracerebral hemorrhage 3 days after γ-knife surgery. He had been suffering from lung cancer with multiple systemic metastasis. Preoperative magnetic resonance images showed two well-defined round lesions with intratumoral hemorrhage in the left frontal and right occipital lobe. There was no bleeding tendency in the hematological exam ination and the patient was normotensive. γ-Knife surgery was performed on both lesions in a single session. However, the patient died of massive intracerebral hemorrhage from the le...
Source: Journal of Radiosurgery - March 1, 2000 Category: Radiology Source Type: research
Case Report: Intracerebral Hemorrhage After γ-Knife Surgery for Metastatic Brain Tumor
Abstract
The authors report a case of a 69-year-old man with metastatic brain tumors who died of spontaneous intracerebral hemorrhage 3 days after γ-knife surgery. He had been suffering from lung cancer with multiple systemic metastasis. Preoperative magnetic resonance images showed two well-defined round lesions with intratumoral hemorrhage in the left frontal and right occipital lobe. There was no bleeding tendency in the hematological examination and the patient was normotensive. γ-Knife surgery was performed on both lesions in a single session. However, the patient died of massive intracerebral he...
Source: Journal of Radiosurgery - March 1, 2000 Category: Radiology Source Type: research
