Identification of Smad-dependent and -independent signaling with transforming growth factor-β type 1/2 receptor inhibition in palatogenesis
The objective of this study was to investigate palatal fusion via TGF-β signaling when TβR1 and TβR2, but not TβR3, were inhibited. In addition, the present study examined the functional balance between Smad-dependent/-independent signaling and related gene expression. Palatal organ cultures were treated with TβR1/2 inhibitor in vitro. Control palates were cultured without inhibitor. We observed histological phenotype of palatal fusion, and evaluation of expression pattern by Western blot or real time RT-PCR. Palatal organ cultures treated with the inhibitor did not fuse and the medial edge epithelium remained at embr...
Source: Journal of Oral Biology and Craniofacial Research - January 17, 2020 Category: Dentistry Source Type: research

Outcomes of luxation injuries to primary teeth-a systematic review
ConclusionFall is the most common cause and regular monitoring is recommended for most of the luxated teeth. Pulp canal obliteration, pulp necrosis and tooth loss due to trauma are prevalent complications observed following luxation. White or yellow brown discoloration of enamel and enamel hypoplasia are the most common undesirable sequelae to permanent teeth. (Source: Journal of Oral Biology and Craniofacial Research)
Source: Journal of Oral Biology and Craniofacial Research - January 9, 2020 Category: Dentistry Source Type: research

The efficacy of Azithromycin on cyclosporine-induced Gingival Enlargement: systematic review and Meta-analysis.
ConclusionAzithromycin has a clinically significant effect on the reduction of cyclosporine-induced gingival enlargement and bleeding on probing. (Source: Journal of Oral Biology and Craniofacial Research)
Source: Journal of Oral Biology and Craniofacial Research - January 3, 2020 Category: Dentistry Source Type: research

Comparative Evaluation of Sealing Ability of Gutta Percha and Resilon as Root Canal Filling Materials- A Systematic Review.
Publication date: Available online 30 December 2019Source: Journal of Oral Biology and Craniofacial ResearchAuthor(s): Pragya Pandey, Himanshi Aggarwal, A.P. Tikku, Arpit Singh, Rhythm Bains, Shambhavi MishraAbstractThis systematic review aims to comparatively evaluate the sealing ability gutta-percha and resilon as root canal filling materials. A Medline search was conducted to identify in-vitro studies published between October 01, 2004 and October 01, 2019, conducted on human extracted teeth, published in English and testing the sealing ability of gutta-percha and resilon as root canal filling materials using fluid filt...
Source: Journal of Oral Biology and Craniofacial Research - December 31, 2019 Category: Dentistry Source Type: research

Effect of Jagged1 on the expression of genes in regulation of osteoblast differentiation and bone mineralization ontology in human dental pulp and periodontal ligament cells
ConclusionJagged1 promote the mRNA expression of several genes in osteoblast differentiation related gene ontology. This could be further employed to identify the mechanism by which Jagged1 promoted osteogenic differentiation in human dental pulp and periodontal ligament cells. (Source: Journal of Oral Biology and Craniofacial Research)
Source: Journal of Oral Biology and Craniofacial Research - December 31, 2019 Category: Dentistry Source Type: research

Nasal conveyance of Methicillin-Resistant Staphylococcus Aureus (MRSA) strains among dental professionals with varying levels of clinical exposure: A comparative study
ConclusionsMRCONS, MSSA and MRSA were shown to increase with an increase in the years of clinical exposure. (Source: Journal of Oral Biology and Craniofacial Research)
Source: Journal of Oral Biology and Craniofacial Research - December 21, 2019 Category: Dentistry Source Type: research

“Outcomes of luxation injuries to primary teeth- a systematic review”
ConclusionFall is the most common cause and monitoring only is the preferred treatment for most of the luxated teeth. Pulp canal obliteration, pulp necrosis and tooth loss due to trauma are prevalent complications observed following luxation. White or yellow brown discoloration of enamel and enamel hypoplasia are the most common undesirable sequelae on permanent teeth. (Source: Journal of Oral Biology and Craniofacial Research)
Source: Journal of Oral Biology and Craniofacial Research - December 18, 2019 Category: Dentistry Source Type: research

Editorial Board
Publication date: January–March 2020Source: Journal of Oral Biology and Craniofacial Research, Volume 10, Issue 1Author(s): (Source: Journal of Oral Biology and Craniofacial Research)
Source: Journal of Oral Biology and Craniofacial Research - December 13, 2019 Category: Dentistry Source Type: research

Editorial Board
Publication date: October–December 2019Source: Journal of Oral Biology and Craniofacial Research, Volume 9, Issue 4Author(s): (Source: Journal of Oral Biology and Craniofacial Research)
Source: Journal of Oral Biology and Craniofacial Research - December 4, 2019 Category: Dentistry Source Type: research

Morphometric analysis of nasopalatine foramen in Sri Lankan population using CBCT
The objective of this study was to identify the morphometeric characteristics of the NPC in group of Sri Lankan people using Cone beam computer tomography (CBCT) and to determine normal morphological course and anatomical variations. Fifty Maxillary CBCT images of anterior maxilla, obtained from the archives of the University Dental Hospital, Peradeniya were retrospectively analyzed to determine the position of the NPC. Morphology, canal dimension of NPC and its relation to the maxilla. Majority had a single opening (48%) or 2 openings (46%). Average diameter of the canal was 3.692 mm with a range of 2 to 6 mm. Majority of...
Source: Journal of Oral Biology and Craniofacial Research - December 3, 2019 Category: Dentistry Source Type: research

Assessment of Eustachian Tube Functioning following surgical intervention of Oral Submucus Fibrosis by using Tympanometry & Audiometry.
This study was conducted to validate the influence of OSMF and its surgical correction on middle ear function and hearing sensitivity. In this study, 20 patients (40 ears) suffering from biopsy proven OSMF (Group 2 & 3) were tested for Middle ear dysfunction and hearing sensitivity using Tympanometry & Audiometry. On Tympanometry, Type A curve was obtained in 29 ears, Type B curve in 11 ears preoperatively. Immediate postoperatively TYPE A curve was obtained in 27 ears, TYPE B curve in 13 ears. After 1 month and 3 month Type B curve was not obtained in any ear. On Audiometry,28 ears showed normal hearing and 12 ears showed...
Source: Journal of Oral Biology and Craniofacial Research - November 29, 2019 Category: Dentistry Source Type: research

Osseodensification –– A systematic review and qualitative analysis of published literature
Publication date: January–March 2020Source: Journal of Oral Biology and Craniofacial Research, Volume 10, Issue 1Author(s): Ninad Milind Padhye, Ashvini Mukul Padhye, Neel B. BhatavadekarAbstractThe recently introduced technique of osseodensification for dental implant involves the use of special drills (Densah) run in a counter-clockwise direction at the osteotomy site. It is claimed that this causes expansion of the osteotomy site, and increases density of the bone in immediate vicinity of the osteotomy. We reviewed published papers on the primary stability attained using this drilling technique. As a secondary finding...
Source: Journal of Oral Biology and Craniofacial Research - November 9, 2019 Category: Dentistry Source Type: research

Polycaprolactone as biomaterial for bone scaffolds: Review of literature
Publication date: Available online 5 November 2019Source: Journal of Oral Biology and Craniofacial ResearchAuthor(s): Ruby Dwivedi, Sumit Kumar, Rahul Pandey, Aman Mahajan, Deepti Nandana, Dhirendra S. Katti, Divya MehrotraAbstract:Bone tissue engineering using polymer based scaffolds have been studied a lot in last decades. Considering the qualities of all the polymers desired to be used as scaffolds, Polycaprolactone (PCL) polyester apart from being biocompatible and biodegradable qualifies to an appreciable level due its easy availability, cost efficacy and suitability for modification. Its adjustable physio-chemical st...
Source: Journal of Oral Biology and Craniofacial Research - November 7, 2019 Category: Dentistry Source Type: research

Cognizance & Oral health status among pregnant females- A Cross Sectional Survey
Publication date: Available online 5 November 2019Source: Journal of Oral Biology and Craniofacial ResearchAuthor(s): Anubha Agarwal, Jaya Chaturvedi, Jyotsna Seth, Ranjeeta Mehta (Source: Journal of Oral Biology and Craniofacial Research)
Source: Journal of Oral Biology and Craniofacial Research - November 7, 2019 Category: Dentistry Source Type: research

Poly hydroxyalkanoates (PHA): role in bone scaffolds
Publication date: Available online 5 November 2019Source: Journal of Oral Biology and Craniofacial ResearchAuthor(s): Ruby Dwivedi, Rahul Pandey, Sumit Kumar, Divya MehrotraABSTRACTPolyhydroxyalkanoates (PHA) are prokaryotic macromolecules accumulated within the cytoplasm as granules. Due to their suitable mechanical properties, biocompatibility, degradation time, ability to be blended, surface modified, and form copolymers, it is widely used in medical devices and as scaffolds in bone tissue engineering. This review describes in brief the production and extraction sources, physico- chemical characteristic, mechanical prop...
Source: Journal of Oral Biology and Craniofacial Research - November 5, 2019 Category: Dentistry Source Type: research