Poly hydroxyalkanoates (PHA): role in bone scaffolds

Publication date: Available online 5 November 2019Source: Journal of Oral Biology and Craniofacial ResearchAuthor(s): Ruby Dwivedi, Rahul Pandey, Sumit Kumar, Divya MehrotraABSTRACTPolyhydroxyalkanoates (PHA) are prokaryotic macromolecules accumulated within the cytoplasm as granules. Due to their suitable mechanical properties, biocompatibility, degradation time, ability to be blended, surface modified, and form copolymers, it is widely used in medical devices and as scaffolds in bone tissue engineering. This review describes in brief the production and extraction sources, physico- chemical characteristic, mechanical properties, degradation rate and applications of various PHAs and its coploymers with special emphasis to its role as scaffolds in bone tissue engineering.
Source: Journal of Oral Biology and Craniofacial Research - Category: Dentistry Source Type: research