Human BDNF rs6265 polymorphism as a mediator for the generalization of contextual anxiety
AbstractThe Met allele of the human brain ‐derived neurotrophic factor (BDNF) gene might be a risk factor for anxiety disorders and is associated with reduced hippocampal volume. Notably, hippocampus plays a crucial role in contextual learning and generalization. The role of theBDNF gene variation in human context ‐conditioning and generalization is still unknown. We investigated 33 carriers of the Met allele (18 females) and 32 homozygous carriers of the Val allele (15 females) with a virtual‐reality context‐conditioning paradigm. Electric stimulations (unconditioned stimulus, US) were unpredictably de livered in ...
Source: Journal of Neuroscience Research - November 7, 2018 Category: Neuroscience Authors: Marta Andreatta,
Dorothea Neueder,
Hannah Genheimer,
Miriam A. Schiele,
Christoph Schartner,
J ürgen Deckert,
Katharina Domschke,
Andreas Reif,
Matthias J. Wieser,
Paul Pauli Tags: RESEARCH ARTICLE Source Type: research
Repeated isoflurane in adult male mice leads to acute and persistent motor decrements with long ‐term modifications in corpus callosum microstructural integrity
We report that repeated isoflurance exposure can lead to persistent motor impairments and long ‐term alteration in white matter microstructural organization in mice. AbstractIsoflurane is a commonly used inhalational anesthetic, clinically and in animal experimental studies. Although it has been reported as safe, recent findings suggest that despite widespread use, isoflurane ‐induced inhalational anesthesia can lead to various pathophysiological and cognitive alterations. Therefore, we aimed to investigate the long‐term behavioral and white matter consequences of repeated isoflurane exposure. Twenty 3‐month‐old ...
Source: Journal of Neuroscience Research - November 5, 2018 Category: Neuroscience Authors: Nikita M. Bajwa,
Jeong B. Lee,
Shina Halavi,
Richard E. Hartman,
Andre Obenaus Tags: RESEARCH ARTICLE Source Type: research
Repeated isoflurane in adult male mice leads to acute and persistent motor decrements with long ‐term modifications in corpus callosum microstructural integrity
Journal of Neuroscience Research, EarlyView. (Source: Journal of Neuroscience Research)
Source: Journal of Neuroscience Research - November 5, 2018 Category: Neuroscience Authors: Nikita M. Bajwa,
Jeong B. Lee,
Shina Halavi,
Richard E. Hartman,
Andre Obenaus Source Type: research
Distribution patterns of the zebrafish neuronal intermediate filaments inaa and inab
In conclusion, we report that the distribution patterns of inaa and inab are phylogenetically conserved in the telencephalon, optic tectum, and cerebellum. Moreover, inaa and inab had different expression patterns in the pineal gland and retina during zebrafish development. Both inaa and inab are neuronal IFs and their functional roles may be different in various aspects of zebrafish neuronal development. (Source: Journal of Neuroscience Research)
Source: Journal of Neuroscience Research - November 2, 2018 Category: Neuroscience Authors: Meng ‐Lin Liao,
Wei‐Hau Peng,
Daphne Kan,
Chung‐Liang Chien Tags: RESEARCH ARTICLE Source Type: research
Distribution patterns of the zebrafish neuronal intermediate filaments inaa and inab
Journal of Neuroscience Research, EarlyView. (Source: Journal of Neuroscience Research)
Source: Journal of Neuroscience Research - November 2, 2018 Category: Neuroscience Authors: Meng ‐Lin Liao,
Wei‐Hau Peng,
Daphne Kan,
Chung‐Liang Chien Source Type: research
Choosing the right cell for spinal cord repair
Journal of Neuroscience Research, EarlyView. (Source: Journal of Neuroscience Research)
Source: Journal of Neuroscience Research - November 1, 2018 Category: Neuroscience Authors: Lyandysha V. Zholudeva,
Michael A. Lane Tags: LETTER TO THE EDITOR Source Type: research
C1q/TNF ‐related protein 9: A novel therapeutic target in ischemic stroke?
AbstractIschemic stroke has become a serious public health problem, which is in need of advanced research on the prevention and treatment. As a newly discovered adipokine, C1q/TNF ‐related protein 9 (CTRP9) plays a vital role in the pathogenesis of coronary atherosclerosis disease (CAD), including regulating energy metabolism, modulating vasomotion, protecting endothelial cells, inhibiting platelet activation, inhibiting pathological vascular remodeling, stabilizing atheros clerotic plaques, and protecting heart. The present review raised a critical question of whether CTRP9 could also have the capacity of protecting the...
Source: Journal of Neuroscience Research - October 31, 2018 Category: Neuroscience Authors: Cui Yang,
Fan Fan,
Darrell Sawmiller,
Jun Tan,
Qingsong Wang,
Yang Xiang Tags: MINIREVIEW Source Type: research
C1q/TNF ‐related protein 9: A novel therapeutic target in ischemic stroke?
Journal of Neuroscience Research, EarlyView. (Source: Journal of Neuroscience Research)
Source: Journal of Neuroscience Research - October 31, 2018 Category: Neuroscience Authors: Cui Yang,
Fan Fan,
Darrell Sawmiller,
Jun Tan,
Qingsong Wang,
Yang Xiang Source Type: research
Aberrant left insular cortex response: A possible pathogenesis of reduced vagal nervous system activity in heart failure? —Reply
Journal of Neuroscience Research, EarlyView. (Source: Journal of Neuroscience Research)
Source: Journal of Neuroscience Research - October 27, 2018 Category: Neuroscience Authors: Xiaopeng Song,
Mary A. Woo,
Rajesh Kumar Source Type: research
Neuronal extracellular microRNAs miR ‐124 and miR‐9 mediate cell–cell communication between neurons and microglia
Journal of Neuroscience Research, EarlyView. (Source: Journal of Neuroscience Research)
Source: Journal of Neuroscience Research - October 27, 2018 Category: Neuroscience Authors: Tatyana Veremeyko,
Inna S. Kuznetsova,
Marina Dukhinova,
Amanda W. Y. Yung,
Ekaterina Kopeikina,
Natasha S. Barteneva,
Eugene D. Ponomarev Source Type: research
The C ‐terminal flanking peptide of neuropeptide Y (NPY) is not essential for seizure‐suppressant actions of prepro‐NPY overexpression in male rats
Journal of Neuroscience Research, EarlyView. (Source: Journal of Neuroscience Research)
Source: Journal of Neuroscience Research - October 27, 2018 Category: Neuroscience Authors: Katia Soud,
S øren Heide Jørgensen,
David Paul Drucker Woldbye,
Andreas Toft Sørensen Source Type: research
Aberrant left insular cortex response: A possible pathogenesis of reduced vagal nervous system activity in heart failure? —Reply
Journal of Neuroscience Research, EarlyView. (Source: Journal of Neuroscience Research)
Source: Journal of Neuroscience Research - October 27, 2018 Category: Neuroscience Authors: Xiaopeng Song,
Mary A. Woo,
Rajesh Kumar Source Type: research
