Self-sampling for cervical screening: Could it overcome some of the barriers to the Pap test?
Conclusions Self-sampling was most popular among women who needed to have a Pap test, and could potentially reach some women who are not participating appropriately in cervical screening. Key barriers to participation could be addressed by providing information about the test being for HPV, and being easier to do properly than a Pap test. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - October 29, 2014 Category: Epidemiology Authors: Mullins, R., Scalzo, K., Sultana, F. Tags: Original Articles Source Type: research

Offering informed choice about breast screening
Over the last few years, there has been growing international concern about the risk of overdiagnosis in breast screening and about how to communicate this to women. There has also been an increasing policy drive to provide people with information to enable them to make an informed choice about screening. In response to this, a novel approach to developing the information about cancer screening has been adopted in England. This approach has integrated the perspectives of people eligible for screening, and experts in public engagement, informed choice, and communicating risk, as well as experts in screening. New information...
Source: Journal of Medical Screening - October 29, 2014 Category: Epidemiology Authors: Forbes, L. J., Ramirez, A.-J., the Expert group on Information about Breast Screening (see below for member list) Tags: Original Articles Source Type: research

Breast cancer mortality trends in Italy by region and screening programme, 1980-2008
Conclusions This earlier decline in three Italian regions could be partially attributable to local organized screening programmes implemented earlier than in the rest of Italy, and to opportunistic screening that became more common in 1990s. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - October 29, 2014 Category: Epidemiology Authors: Gorini, G., Zappa, M., Cortini, B., Martini, A., Mantellini, P., Ventura, L., Carreras, G. Tags: Original Articles Source Type: research

Cost-effectiveness of annual versus biennial screening mammography for women with high mammographic breast density
Conclusion There is considerable uncertainty about the incremental cost-effectiveness of annual mammography. Further research on the comparative effectiveness of screening strategies for women with high mammographic breast density is warranted, particularly as digital mammography and density measurement become more widespread, before cost-effectiveness can be reevaluated. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - October 29, 2014 Category: Epidemiology Authors: Pataky, R., Ismail, Z., Coldman, A. J., Elwood, M., Gelmon, K., Hedden, L., Hislop, G., Kan, L., McCoy, B., Olivotto, I. A., Peacock, S. Tags: Original Articles Source Type: research

Current office-based hearing screening questions fail to identify adolescents at risk for hearing loss
Conclusions Most Bright Futures questions were not associated with adolescent hearing loss. An objective adolescent hearing screen should be considered in the recommended schedule of preventive care, instead of the current risk-based subjective assessment. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - October 29, 2014 Category: Epidemiology Authors: Sekhar, D. L., Zalewski, T. R., King, T. S., Paul, I. M. Tags: Original Articles Source Type: research

Co-inheritance of {alpha}-thalassaemia and {beta}-thalassaemia in a prenatal screening population in mainland China
Conclusion Our results suggest that it could be valuable to study co-existing α-globin mutations in subjects with β-thalassaemia trait in a prenatal screening programme, especially in populations with a high prevalence of haemoglobinopathies. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - October 29, 2014 Category: Epidemiology Authors: Li, J., Xie, X.-M., Liao, C., Li, D.-Z. Tags: Original Articles Source Type: research

Breast cancer screening, body mass index and prognosis benefit
(Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 22, 2014 Category: Epidemiology Authors: Montella, M., Grimaldi, M., Rinaldo, M., Capasso, I., D' Aiuto, M., D'Aiuto, G., Ciliberto, G., Crispo, A. Tags: Letter to the Editor Source Type: research

Pre-marital screening for beta thalassaemia in Pakistan: an insight
(Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 22, 2014 Category: Epidemiology Authors: Shariq, M., Moiz, B., Zaidi, N., Bin Azhar, W., Iqbal, W., Humaira, A., Memon, R. N. Tags: Research Letter Source Type: research

A whole-population profile of HPV testing as a test of cure for high-grade cervical dysplasia in NSW, Australia
Conclusions Cure rates in women with follow-up testing according to NHMRC guidelines are high. Further studies are needed of the high proportion of women with negative cytology classed as not cured due to HPV positivity, and of the high proportion of women with high grade dysplasia who had one follow-up HPV test only. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 22, 2014 Category: Epidemiology Authors: Morrell, S., Qian, L. Tags: Original Articles Source Type: research

Five-year experience of organized colorectal cancer screening in a Swedish population - increased compliance with age, female gender, and subsequent screening round
Conclusion The strong organization of the programme contributed to a high compliance rate, that increased by screening round. The lower participation rate among men and among individuals at younger ages needs further attention. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 22, 2014 Category: Epidemiology Authors: Blom, J., Kilpelainen, S., Hultcrantz, R., Tornberg, S. Tags: Original Articles Source Type: research

Test Characteristics of Faecal Immunochemical Tests (FIT) Compared with Optical Colonoscopy
Conclusions The sensitivity of a single-sample FIT for advanced adenomas or cancer was low. Individuals with distal adenomas had a higher odds of testing positive than those with proximal lesions or no lesions. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 22, 2014 Category: Epidemiology Authors: Levy, B. T., Bay, C., Xu, Y., Daly, J. M., Bergus, G., Dunkelberg, J., Moss, C. Tags: Original Articles Source Type: research

Home-based screening for biliary atresia using infant stool colour cards: A large-scale prospective cohort study and cost-effectiveness analysis
Conclusions A BA ISCC screening programme targeting families of newborns is feasible in Canada. Passive distribution of ISCC at maternity is potentially effective and highly cost-effective. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 22, 2014 Category: Epidemiology Authors: Schreiber, R. A., Masucci, L., Kaczorowski, J., Collet, J., Lutley, P., Espinosa, V., Bryan, S. Tags: Original Articles Source Type: research

Routine screening for {alpha}-thalassaemia using an immunochromatographic strip assay for haemoglobin Bart's
Conclusion The results showed a high sensitivity for screening for α0-thalassaemia using IC strip assay for Hb Bart's. This simple method, used in combination with conventional screening protocols, should lead to a significant reduction in the number of referral cases for DNA analysis. Cost effectiveness in each population should be taken into consideration. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 22, 2014 Category: Epidemiology Authors: Prayalaw, P., Fucharoen, G., Fucharoen, S. Tags: Original Articles Source Type: research

Antenatal detection of Edwards (Trisomy 18) and Patau (Trisomy 13) syndrome: England and Wales 2005-2012
Conclusions Almost 700 women per year had a pregnancy with Edwards or Patau syndrome. Over 90% of these pregnancies were detected antenatally, with the increased use of first trimester screening for Down’s syndrome resulting in the reduction in the mean gestational age at diagnosis of these syndromes. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 22, 2014 Category: Epidemiology Authors: Springett, A. L., Morris, J. K. Tags: Original Articles Source Type: research

The estimation of median nuchal translucency values between 10 and 14 weeks of pregnancy
Nuchal translucency (NT) is a useful marker in antenatal screening for Down’s syndrome in the late first trimester of pregnancy. NT measurements increase with increasing crown rump length (CRL) so multiple of the median (MoM) values are used to allow for this. Log-linear and log-quadratic regressions of NT in relation to CRL have previously been proposed to calculate MoM values. Using data on 288,079 women, these models were compared with a log-sigmoid regression. The log-linear regression overestimated the median NT above a CRL of 75 mm; for example, 1.9 mm versus 1.8 mm observed at 75–79 mm, and 2.0 mm versus...
Source: Journal of Medical Screening - June 6, 2014 Category: Epidemiology Authors: Bestwick, J. P., Huttly, W. J., Wald, N. J. Tags: Short Communication Source Type: research