Neonatal screening external quality assessment in China, 2014
Conclusion Most of the quantitative results were acceptable and the overall correct recognition rates in qualitative results approached 100%. Distributing more challenging samples and increasing the range of concentrations of EQA samples will improve standards in future assessments. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - November 5, 2015 Category: Epidemiology Authors: Zhong, K., Wang, W., He, F., Wang, Z. Tags: Original Articles Source Type: research

Performance of antenatal reflex DNA screening for Down's syndrome
Conclusion Reflex DNA testing substantially reduces the FPR with a relatively small loss in detection compared with universal DNA testing, and reduces patient anxiety by avoiding the recall of women for DNA testing. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - November 5, 2015 Category: Epidemiology Authors: Wald, N. J., Bestwick, J. P. Tags: Original Articles Source Type: research

Informed Decision-Making and Breast Cancer Screening
(Source: Journal of Medical Screening)
Source: Journal of Medical Screening - November 5, 2015 Category: Epidemiology Authors: Sasieni, P., Smith, R., Duffy, S. Tags: Editorial Source Type: research

Barrett's Oesophagus Surveillance versus endoscopy at need Study (BOSS): protocol and analysis plan for a multicentre randomized controlled trial
Conclusions This randomized trial will provide data to evaluate the efficacy and cost-effectiveness of screening BO patients for OAC. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 24, 2015 Category: Epidemiology Authors: Old, O., Moayyedi, P., Love, S., Roberts, C., Hapeshi, J., Foy, C., Stokes, C., Briggs, A., Jankowski, J., Barr, H., the BOSS Trial Team Tags: Original Articles Source Type: research

Lung cancer risk by years since quitting in 30+ pack year smokers
Conclusions Lung cancer risk decreases gradually with YSQ in 30+ pack year former smokers. A range of upper limits on YSQ may be supportable for LDCT screening. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 24, 2015 Category: Epidemiology Authors: Pinsky, P. F., Zhu, C. S., Kramer, B. S. Tags: Original Articles Source Type: research

Exploring the trend of increased cervical intraepithelial neoplasia detection rates in the Netherlands
Conclusions The implementation of liquid-based cytology contributed to the CIN increase. If some of these extra detected CIN are regressive this leads to overdiagnosis. Other factors, such as an increased cervical cancer risk, and implementation of imaging-assisted reading, could also have contributed. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 24, 2015 Category: Epidemiology Authors: Rozemeijer, K., van Kemenade, F. J., Penning, C., Matthijsse, S. M., Naber, S. K., van Rosmalen, J., van Ballegooijen, M., de Kok, I. M. Tags: Original Articles Source Type: research

Interval cancer rates in the Irish national breast screening programme
Conclusion Interval breast cancer rates for the first years of the programme are within acceptable limits and are comparable with those in other European programmes. Nationwide roll-out together with the adoption of digital mammography may have an impact on interval cancer rates in future years. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 24, 2015 Category: Epidemiology Authors: O'Brien, K. M., Dwane, F., Kelleher, T., Sharp, L., Comber, H. Tags: Original Articles Source Type: research

Estimates of over-diagnosis of breast cancer due to population-based mammography screening in South Australia after adjustment for lead time effects
Conclusions We estimated 8% over-diagnosis for invasive breast cancer and 12% inclusive of DCIS cancers due to mammography screening among women aged 40–84. These estimates may overstate the extent of over-diagnosis if the increasing prevalence of breast cancer risk factors has led to higher background incidence than projected. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 24, 2015 Category: Epidemiology Authors: Beckmann, K., Duffy, S. W., Lynch, J., Hiller, J., Farshid, G., Roder, D. Tags: Original Articles Source Type: research

Participation rates for organized colorectal cancer screening programmes: an international comparison
Conclusion Comparisons among CRC screening programmes should be made cautiously, given differences in organization, target populations, and interpretation of indicators. More meaningful comparisons are possible if rates are calculated across a uniform age range, by gender, and separately for people invited for the first time vs. previously. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 24, 2015 Category: Epidemiology Authors: Klabunde, C., Blom, J., Bulliard, J.-L., Garcia, M., Hagoel, L., Mai, V., Patnick, J., Rozjabek, H., Senore, C., Tornberg, S. Tags: Original Articles Source Type: research

A study of whether automated Diabetic Retinopathy Image Assessment could replace manual grading steps in the English National Screening Programme
Conclusions Retinopathy prevalence was similar to other English diabetic screening programmes, so findings should be generalizable. The study population size will allow the detection of differences in screening performance between the human and automated grading systems as small as 2%. The project will compare performance and economic costs of manual versus automated systems. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 24, 2015 Category: Epidemiology Authors: Kapetanakis, V. V., Rudnicka, A. R., Liew, G., Owen, C. G., Lee, A., Louw, V., Bolter, L., Anderson, J., Egan, C., Salas-Vega, S., Rudisill, C., Taylor, P., Tufail, A. Tags: Original Articles Source Type: research

Screening for breast cancer by molecular testing for three founder mutations in the BRCA1 and BRCA2 genes among women of Ashkenazi Jewish heritage
(Source: Journal of Medical Screening)
Source: Journal of Medical Screening - August 24, 2015 Category: Epidemiology Authors: Palomaki, G. E. Tags: Editorial Source Type: research

The prevalence of medical reasons for non-participation in the Scottish breast and bowel cancer screening programmes
Conclusion These patients may not benefit from screening while also being distressed by receiving an invitation. This issue also makes accurate monitoring and target-setting for improving uptake difficult. Further work is needed to estimate robustly the extent to which medical reasons account for screening non-participation in a larger population. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - May 12, 2015 Category: Epidemiology Authors: Mead, L., Porteous, L., Tait, M., Stoker, R., Payne, S., Calvert, C., Maxwell, D., Katikireddi, S. Tags: Short Communications Source Type: research

Antenatal screening for Down's syndrome, trisomy 18, and trisomy 13: Reporting a single screening result for all three
Conclusions Reporting a single risk estimate for the three disorders is less confusing than reporting separate risks and can yield the same or better screening performance. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - May 12, 2015 Category: Epidemiology Authors: Bestwick, J. P., Wald, N. J. Tags: Short Communications Source Type: research

Consultation rates in cervical screening non-attenders: opportunities to increase screening uptake in GP primary care
Conclusions Over half of cervical screening non-attenders present to their GP at least once a year, in over 75% of practices. This represents a good opportunity for improving coverage by offering an alternative form of screening, such as self-sampling for human papillomavirus testing. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - May 12, 2015 Category: Epidemiology Authors: Lim, A. W. W., Sasieni, P. Tags: Original Articles Source Type: research

Measuring the burden of interval cancers in long-standing screening mammography programmes
Conclusion The value of the PICR is hugely influenced by which method is applied, whereas the ICR is calculated purely on data available within programmes. We find that the PICR, the establishing indicator for sensitivity, could preferably be replaced by the ICR. (Source: Journal of Medical Screening)
Source: Journal of Medical Screening - May 12, 2015 Category: Epidemiology Authors: Andersen, S. B., Tornberg, S., Kilpelainen, S., Lynge, E., Njor, S. H., Von Euler-Chelpin, M. Tags: Original Articles Source Type: research