Multimodal imaging reveals temporal and spatial microglia and matrix metalloproteinase activity after experimental stroke
chäfers, Lydia M Sorokin, Michael T Kuhlmann & Andreas H Jacobs (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - October 30, 2015 Category: Neuroscience Authors: Bastian ZinnhardtThomas VielLydia WachsmuthAlexis VrachimisStefan WagnerHans-Jörg BreyholzAndreas FaustSven HermannKlaus KopkaCornelius FaberFrédéric DolléSabina PappataAnna M PlanasBertrand TavitianMichael SchäfersLydia M SorokinMichael T KuhlmannAn Tags: microglia matrix metalloproteases perfusion positron emission tomography stroke Source Type: research

Positron emission tomography/magnetic resonance hybrid scanner imaging of cerebral blood flow using 15O-water positron emission tomography and arterial spin labeling magnetic resonance imaging in newborn piglets
Positron emission tomography/magnetic resonance hybrid scanner imaging of cerebral blood flow using 15O-water positron emission tomography and arterial spin labeling magnetic resonance imaging in newborn piglets Journal of Cerebral Blood Flow & Metabolism 35, 1703 (November 2015). doi:10.1038/jcbfm.2015.139 Authors: Julie B Andersen, William S Henning, Ulrich Lindberg, Claes N Ladefoged, Liselotte Højgaard, Gorm Greisen & Ian Law (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - October 30, 2015 Category: Neuroscience Authors: Julie B AndersenWilliam S HenningUlrich LindbergClaes N LadefogedLiselotte HøjgaardGorm GreisenIan Law Tags: 15O-water PET arterial spin labeling neonatology PET/MR Source Type: research

A method for reducing the effects of motion contamination in arterial spin labeling magnetic resonance imaging
au M Ances (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - September 30, 2015 Category: Neuroscience Authors: Aaron B TanenbaumAbraham Z SnyderMatthew R BrierBeau M Ances Tags: arterial spin labeling ASL cerebral blood flow measurement perfusion-weighted MRI Source Type: research

Selective astrocytic endothelin-1 overexpression contributes to dementia associated with ischemic stroke by exaggerating astrocyte-derived amyloid secretion
g & Sookja K Chung (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - September 30, 2015 Category: Neuroscience Authors: Victor K L HungPatrick K K YeungAngela K W LaiMaggie C Y HoAmy C Y LoKevin C ChanEd X K WuStephen S M ChungChi W CheungSookja K Chung Tags: Alzheimer’s disease amyloidosis astrocytes endothelin-1 ischemic stroke Source Type: research

Association between the perfusion/diffusion and diffusion/FLAIR mismatch: data from the AXIS2 trial
Association between the perfusion/diffusion and diffusion/FLAIR mismatch: data from the AXIS2 trial Journal of Cerebral Blood Flow & Metabolism 35, 1681 (October 2015). doi:10.1038/jcbfm.2015.108 Authors: Anke Wouters, Patrick Dupont, Erich B Ringelstein, Bo Norrving, Angel Chamorro, Martin Grond, Rico Laage, Armin Schneider, Guido Wilms, Götz Thomalla, Robin Lemmens & Vincent N Thijs (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - September 30, 2015 Category: Neuroscience Authors: Anke WoutersPatrick DupontErich B RingelsteinBo NorrvingAngel ChamorroMartin GrondRico LaageArmin SchneiderGuido WilmsGötz ThomallaRobin LemmensVincent N Thijs Tags: brain imaging brain ischemia diffusion-weighted MRI perfusion-weighted MRI Source Type: research

Early disrupted neurovascular coupling and changed event level hemodynamic response function in type 2 diabetes: an fMRI study
amp; Miguel Castelo-Branco (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - September 30, 2015 Category: Neuroscience Authors: João V DuarteJoão M S PereiraBruno QuenderaMiguel RaimundoCarolina MorenoLeonor GomesFrancisco CarrilhoMiguel Castelo-Branco Tags: brain imaging cerebral hemodynamics diabetes MRI neurovascular coupling Source Type: research

Noninvasive quantification of cerebral metabolic rate for glucose in rats using 18F-FDG PET and standard input function
Takashi Hanakawa (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - September 30, 2015 Category: Neuroscience Authors: Yuki HoriNaoki IharaNoboru TeramotoMasako KunimiManabu HondaKoichi KatoTakashi Hanakawa Tags: cerebral metabolic rate for glucose 18F-FDG non-invasive quantification small animal PET standard input function Source Type: research

Arginase I release from activated neutrophils induces peripheral immunosuppression in a murine model of stroke
; Allen Waziri (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - September 30, 2015 Category: Neuroscience Authors: Trisha R SippelTakeru ShimizuFrank StrnadRichard J TraystmanPaco S HersonAllen Waziri Tags: basic science brain ischemia immunology immunosuppression leukocytes T-cells Source Type: research

Shear-dependent attenuation of cellular ROS levels can suppress proinflammatory cytokine injury to human brain microvascular endothelial barrier properties
M Cummins (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - September 30, 2015 Category: Neuroscience Authors: Keith D RochfortLaura E CollinsAlisha McLoughlinPhilip M Cummins Tags: blood–brain barrier cerebrovascular disease endothelium free radicals Source Type: research

Inhibition of histone methyltransferases SUV39H1 and G9a leads to neuroprotection in an in vitro model of cerebral ischemia
tefanie Märschenz (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - September 30, 2015 Category: Neuroscience Authors: Sophie SchweizerChristoph HarmsHeike LerchJennifer FlynnJochen HechtFerah YildirimAndreas MeiselStefanie Märschenz Tags: BDNF G9a histone methylation ischemia SUV39H1 Source Type: research

Vascular permeability in cerebral cavernous malformations
istoforidis & Issam A Awad (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - September 30, 2015 Category: Neuroscience Authors: Abdul G MikatiOmaditya KhannaLingjiao ZhangRomuald GirardRobert ShenkarXiaodong GuoAkash ShahHenrik BW LarssonHuan TanLuying LiMatthew S WishnoffChangbin ShiGregory A ChristoforidisIssam A Awad Tags: cerebrovascular disease intracranial hemorrhage MRI neuroradiology neurosurgery Source Type: research

CX3CL1/CX3CR1-mediated microglia activation plays a detrimental role in ischemic mice brain via p38MAPK/PKC pathway
CX3CL1/CX3CR1-mediated microglia activation plays a detrimental role in ischemic mice brain via p38MAPK/PKC pathway Journal of Cerebral Blood Flow & Metabolism 35, 1623 (October 2015). doi:10.1038/jcbfm.2015.97 Authors: Yong Liu, Xiao-Mei Wu, Qian-Qian Luo, Suna Huang, Qing-Wu Qian Yang, Fa-Xiang Wang, Ya Ke & Zhong-Ming Qian (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - September 30, 2015 Category: Neuroscience Authors: Yong LiuXiao-Mei WuQian-Qian LuoSuna HuangQing-Wu Qian YangFa-Xiang WangYa KeZhong-Ming Qian Tags: bilateral common carotid artery stenosis (BCAS) brain ischemic injury CX3CL1 (fractalkine)/CX3CR1 microglia activation oxygen–glucose deprivation (OGD) p38MAPK/PKC Source Type: research

Method for rapid MRI quantification of global cerebral metabolic rate of oxygen
; Felix W Wehrli (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - September 30, 2015 Category: Neuroscience Authors: Suliman BarhoumMichael C LanghamJeremy F MaglandZachary B RodgersCheng LiChamith S RajapakseFelix W Wehrli Tags: cerebral blood flow measurement energy metabolism magnetic resonance MRI Source Type: research

Reduced blood flow in normal white matter predicts development of leukoaraiosis
Shelagh B Coutts (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - September 30, 2015 Category: Neuroscience Authors: Manya BernbaumBijoy K MenonGordon FickEric E SmithMayank GoyalRichard FrayneShelagh B Coutts Tags: cerebral blood flow leukoaraiosis white matter hyperintensities Source Type: research

The effects of delayed reduction of tonic inhibition on ischemic lesion and sensorimotor function
amp; Bojana Stefanovic (Source: Journal of Cerebral Blood Flow and Metabolism)
Source: Journal of Cerebral Blood Flow and Metabolism - September 30, 2015 Category: Neuroscience Authors: Evelyn M R LakeJoydeep ChaudhuriLynsie ThomasonRafal JanikMilan GangulyMary BrownJoAnne McLaurinDale CorbettGreg J StaniszBojana Stefanovic Tags: behavioral recovery chronic treatment GABA antagonism magnetic resonance imaging stroke rat modeling Source Type: research