Cytotoxic Effect of Photoluminescent RE3+ Doped Ca3(PO4)2 Nanorods on Breast Cancer Cell Lines
ConclusionThe results suggest that Ca3(PO4)2:Tb3+, Ce3+ phosphor may be useful for therapeutic application in clinical settings.Graphical abstract (Source: IRBM)
Source: IRBM - May 24, 2019 Category: Biomedical Engineering Source Type: research

A Simple and Effective Approach for Digitization of the CTG Signals from CTG Traces
ConclusionsThe obtained results show that the proposed method is quite efficient in digitization of the CTG signals. In future works, this tool will be used to digitize the recordings belonging to the antepartum period collected from the obstetrics clinics in Medical Park Hospital in Elazığ, Turkey.Graphical abstract (Source: IRBM)
Source: IRBM - May 23, 2019 Category: Biomedical Engineering Source Type: research

Editorial Board
Publication date: June 2019Source: IRBM, Volume 40, Issue 3Author(s): (Source: IRBM)
Source: IRBM - May 21, 2019 Category: Biomedical Engineering Source Type: research

Raman Spectroscopy: Application in Periodontal and Oral Regenerative Surgery for Bone Evaluation
ConclusionsThe spectra intensity variation related to the specific bone constituents' concentrations, before and after healing, is reflecting the rate of the healing process mostly by the changes that occurred for the calcified tissues. Moreover, the bone sample fluorescence is related to the collagen content, enabling the quantification of healing process.Clinical relevanceTherefore, since a complete evaluation of the processed spectra offers quantitative information for bone samples, Raman spectroscopy can be considered a viable investigation method (even forensics) for periodontal disease and bone quality assessment.Gra...
Source: IRBM - May 15, 2019 Category: Biomedical Engineering Source Type: research

A Smart Phone Application for the Mothers of Premature Infants
ConclusionMothers of premature infants tend to increase their knowledge about their infant's requirements. The application designed in the current study can help mothers to be informed about the premature infants' requirements. Further research is required to evaluate the effectiveness of using this mobile application.Graphical abstract (Source: IRBM)
Source: IRBM - May 10, 2019 Category: Biomedical Engineering Source Type: research

HMM-based Supervised Machine Learning Framework for the Detection of fECG R-R Peak Locations
ConclusionTwo primary challenges in these methods are finding the right reference threshold for the normalization of the extracted fECG signal during the initial trials and limitation of discrete frame work of HMM signal (converted from continuous time) which only offers a countable number of levels in observations. By feeding the posterior probabilities, obtained from SVM, into HMM, as emission probabilities, can further improve the accuracy of fQRS location detection.Graphical abstractBlock diagram of different stages of fECG QRS location detection using HMM. (Source: IRBM)
Source: IRBM - May 9, 2019 Category: Biomedical Engineering Source Type: research

Walsh Hadamard Transform for Simple Linear Iterative Clustering (SLIC) Superpixel Based Spectral Clustering of Multimodal MRI Brain Tumor Segmentation
Publication date: Available online 7 May 2019Source: IRBMAuthor(s): M. Angulakshmi, G.G. Lakshmi PriyaAbstractThe automated brain tumor segmentation methods are challenging due to the diverse nature of tumors. Recently, the graph based spectral clustering method is utilized for brain tumor segmentation to make high-quality segmentation output. In this paper, a new Walsh Hadamard Transform (WHT) texture for superpixel based spectral clustering is proposed for segmentation of a brain tumor from multimodal MRI images. First, the selected kernels of WHT are utilized for creating texture saliency maps and it becomes the input f...
Source: IRBM - May 9, 2019 Category: Biomedical Engineering Source Type: research

Assessment of Interaction Between Cardio-Respiratory Signals Using Directed Coherence on Healthy Subjects During Postural Change
ConclusionThe proposed directed coherence approach detects the cardio-respiratory regulation during postural change and provide information about coupling changes during this transition.Graphical abstract (Source: IRBM)
Source: IRBM - April 25, 2019 Category: Biomedical Engineering Source Type: research

A Novel Technique to Detect Caries Lesion Using Isophote Concepts
The objective of this work is to design a system to assist dentists to detect caries lesion quickly and more accurately. Deep learning based method is not suitable for this application because there is not enough training set is available to prepare the pre-trained model properly for deep learning. Traditional handcrafted method is desirable for such situation.MethodsDental x-ray not only contains the image of teeth and bonny structure of the jaws but also the tissues within the gum regions. So normal texture based segmentation is not enough to detect the caries lesion. In x-ray, caries lesion looks like a catchment basin,...
Source: IRBM - April 25, 2019 Category: Biomedical Engineering Source Type: research

A Comparison of ECG Signal Pre-Processing Using FrFT, FrWT and IPCA for Improved Analysis
ConclusionCorrect analysis of the acquired ECG signal is the main challenge for cardiologist due to involvement of various types of noises (high and low frequency). Twenty two real time ECG records have been evaluated based on various FoM such as SNR, Se, Acc and DER for the proposed FrWT and existing FrFT and IPCA preprocessing techniques. Acquired real-time ECG database in normal and disease situations is used for the purpose. The values of FoMs indicate high SNR and better detection of R-peaks in a ECG signal which is important for the diagnosis of cardiovascular disease. The proposed FrWT outperforms all other techniqu...
Source: IRBM - April 18, 2019 Category: Biomedical Engineering Source Type: research

State of the Art Technology for Bone Tissue Engineering and Drug Delivery
ConclusionThe biodegradable beads used as a local drug delivery system are ubiquitous in surgery to treat post-operative infections but does not play any role in tissue regeneration. The use of this clinically accepted drug delivery technique in bone regeneration is an alternative way for the treatment on several bone infections (especially osteomyelitis and arthritis associated with tuberculosis). It is predicted to be the future of organ replacement and treatment.Graphical abstract (Source: IRBM)
Source: IRBM - March 20, 2019 Category: Biomedical Engineering Source Type: research

Editorial Board
Publication date: March 2019Source: IRBM, Volume 40, Issue 2Author(s): (Source: IRBM)
Source: IRBM - March 13, 2019 Category: Biomedical Engineering Source Type: research

A New Method for Nonlinear Dynamic Analysis of the Multi-kinetics Neural Mass Model
ConclusionThe Lorenz plot of EEG signals with different rhythms presents different distribution. It is an effective nonlinear analysis method for EEG signals.Graphical abstract (Source: IRBM)
Source: IRBM - March 8, 2019 Category: Biomedical Engineering Source Type: research

Eigenspace Time Frequency Based Features for Accurate Seizure Detection from EEG Data
ConclusionExperimental results show that the novel features have successfully represented the characteristics of the underlying disease phenomenon from EEG data. Also, we conclude that learning based classifiers are better suited for this application, compared to Bayesian classifiers that have difficulty in adapting to the varying nature of the features' probability distribution function.Graphical abstract (Source: IRBM)
Source: IRBM - March 4, 2019 Category: Biomedical Engineering Source Type: research

Hybrid Nature Inspired SMO-GBM Classifier for Exudate Classification on Fundus Retinal Images
Conclusion: The proposed approach provides detection and grading of diabetic retinopathy. The abnormality is further categories as soft, moderate and severe. The hybrid SMO-GBM classifier yields a better statistical metrics than the existing exudates classification approaches.Graphical abstract (Source: IRBM)
Source: IRBM - February 26, 2019 Category: Biomedical Engineering Source Type: research