Current evidence for the treatment of hypothyroidism with levothyroxine/levotriiodothyronine combination therapy versus levothyroxine monotherapy
ConclusionsPersistent symptoms in patients who are biochemically euthyroid with LT4 monotherapy may be caused by several other conditions unrelated to thyroid function, and their cause should be aggressively investigated by the clinician. (Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - January 30, 2018 Category: Internal Medicine Authors: James V. Hennessey, Ramon Espaillat Tags: REVIEW ARTICLE Source Type: research

Evidence in support of hyperkalaemia management strategies: A systematic literature review
ConclusionsDespite hyperkalaemia being associated with several chronic diseases, there is a paucity of high‐quality randomised evidence on long‐established treatment options (SPS and CPS) and a limited evidence base for hyperkalaemia management with these agents. (Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - January 30, 2018 Category: Internal Medicine Authors: Eirini Palaka, Saoirse Leonard, Amy Buchanan ‐Hughes, Anna Bobrowska, Bryony Langford, Susan Grandy Tags: SYSTEMATIC REVIEW Source Type: research

Erectile dysfunction and testosterone deficiency as cardiovascular risk factors?
Summary Graham Jackson introduced the concept that erectile dysfunction was a marker for undiagnosed cardiovascular disease and future events. Unfortunately this had had modest impact on CVD management as ED is not incorporated into current risk calculators. In this paper, we examine recent evidence as to whether ED should be upgraded to a risk factor, especially with the high predictive value in younger men. In the Princeton 3 guidelines, he recognised the important impact of testosterone deficiency (TD) on all‐cause and cardiovascular mortality. Recent evidence suggests that testosterone therapy to target levels and fo...
Source: International Journal of Clinical Practice - January 30, 2018 Category: Internal Medicine Authors: Geoffrey Hackett, Michael Kirby Tags: PERSPECTIVE Source Type: research

Our digital world: Are monthly issues anachronistic?
(Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - January 29, 2018 Category: Internal Medicine Authors: Leslie Citrome Tags: EDITORIAL Source Type: research

Issue Information
(Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - January 29, 2018 Category: Internal Medicine Tags: ISSUE INFORMATION Source Type: research

Inappropriate medication use and polypharmacy in end ‐stage cancer patients: Isn't it the family doctor's role to de‐prescribe much earlier?
International Journal of Clinical Practice, EarlyView. (Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - January 23, 2018 Category: Internal Medicine Source Type: research

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International Journal of Clinical Practice, Ahead of Print. (Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - January 23, 2018 Category: Internal Medicine Source Type: research

Antibiotic allergy labels —the impact of taking a clinical history
International Journal of Clinical Practice, EarlyView. (Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - January 17, 2018 Category: Internal Medicine Source Type: research

Real ‐world clinical outcomes and predictors of glycaemic and weight response to exenatide once weekly in patients with type 2 diabetes: The CIBELES project
International Journal of Clinical Practice, EarlyView. (Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - January 17, 2018 Category: Internal Medicine Source Type: research

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International Journal of Clinical Practice, Ahead of Print. (Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - January 17, 2018 Category: Internal Medicine Source Type: research

Real ‐world clinical outcomes and predictors of glycaemic and weight response to exenatide once weekly in patients with type 2 diabetes: The CIBELES project
ConclusionsIn a real‐world setting, ExQW significantly decreased A1C, weight, blood pressure and lipids at 6 months. Our study identified higher baseline A1C as the sole independent predictor of glycaemic response to ExQW and higher BMI and previous DDP4i treatment as predictive factors of meaningful weight response. (Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - January 17, 2018 Category: Internal Medicine Authors: Juan Jos é Gorgojo‐Martínez, Manuel Angel Gargallo‐Fernández, Miguel Brito‐Sanfiel, Arturo Lisbona‐Catalán Tags: ORIGINAL PAPER Source Type: research

Patients' preferences for coronary bypass grafting or staged percutaneous coronary intervention in multi ‐vessel coronary artery disease
International Journal of Clinical Practice, EarlyView. (Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - January 9, 2018 Category: Internal Medicine Source Type: research

Dedicated warfarin care programme results in superior warfarin control in Queensland, Australia
International Journal of Clinical Practice, EarlyView. (Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - January 9, 2018 Category: Internal Medicine Source Type: research