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Monotherapy versus combination therapy against nonbacteremic carbapenem-resistant gram-negative infections: a retrospective observational study
Conclusions: In our retrospective single-center series of CRGNB nonbacteremic infections, CCCT was not superior to CMT. Multicenter large observational studies or prospective randomized clinical trials are the need of the hour. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - December 14, 2017 Category: Intensive Care Authors: Abdul Ghafur Vidyalakshmi Devarajan T Raja Jose Easow MA Raja Sankar Sreenivas Balasubramaniam Ramakrishnan SG Raman Dedeepiya Devaprasad Balaji Venkatachalam Ramesh Nimmagadda Source Type: research

Clinical profile of patients admitted with hyponatremia in the medical intensive care unit
Prakash Babaliche, Siddharth Madnani, Sajal KamatIndian Journal of Critical Care Medicine 2017 21(12):819-824 Background and Aims: Hyponatremia is the predominant electrolyte abnormality with an incidence rate of approximately 22%. It is the leading cause of morbidity and mortality with scarce data in Indian intensive care settings. The aim of this study is to evaluate the clinical features and etiology of hyponatremia in patients admitted to an Intensive Care Unit (ICU) of a tertiary care hospital. Materials and Methods: A 1-year prospective cross-sectional observational study was conducted, including 100 adul...
Source: Indian Journal of Critical Care Medicine - December 14, 2017 Category: Intensive Care Authors: Prakash Babaliche Siddharth Madnani Sajal Kamat Source Type: research

Tropical fevers in Indian intensive care units: A prospective multicenter study
Sunit Singhi, Narendra Rungta, Karthi Nallasamy, Ashish Bhalla, JV Peter, Dhruva Chaudhary, Rajesh Mishra, Prakash Shastri, Rajesh Bhagchandani, TD Chugh, for Indian Society of Critical Care Medicine Research Group Indian Journal of Critical Care Medicine 2017 21(12):811-818 Background and Aims: Infections in tropics often present as undifferentiated fevers with organ failures. We conducted this nationwide study to identify the prevalence, profile, resource utilization, and outcome of tropical fevers in Indian Intensive Care Units (ICUs). Materials and Methods: This was a multicenter prospective observational study done i...
Source: Indian Journal of Critical Care Medicine - December 14, 2017 Category: Intensive Care Authors: Sunit Singhi Narendra Rungta Karthi Nallasamy Ashish Bhalla JV Peter Dhruva Chaudhary Rajesh Mishra Prakash Shastri Rajesh Bhagchandani TD Chugh for Indian Society of Critical Care Medicine Research Group Source Type: research

Integrative weaning index: A few observations
Animesh RayIndian Journal of Critical Care Medicine 2017 21(11):805-806 (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - November 13, 2017 Category: Intensive Care Authors: Animesh Ray Source Type: research

Accidental ingestion of traces of cyanide: A clinical experience
Sadananda B NaikIndian Journal of Critical Care Medicine 2017 21(11):804-805 (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - November 13, 2017 Category: Intensive Care Authors: Sadananda B Naik Source Type: research

Influenza B virus triggering macrophage activation syndrome in an infant
We report a 10-month-old female infant with fever, convulsions, and hepatosplenomegaly. Laboratory data of bicytopenia, low erythrocyte sedimentation rate, and elevated liver enzymes suggested MAS. This was supported by the presence of hyperferritinemia with hypertriglyceridemia. MAS was triggered by influenza B virus. She responded to treatment with immunoglobulin and steroid. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - November 13, 2017 Category: Intensive Care Authors: K Jayashree Suchetha Rao Nutan Kamath Source Type: research

Malpositioning of central venous catheter from right to left subclavian vein: A rare complication
P Rajendra Takhar, Bunkar Motilal, Arya SavitaIndian Journal of Critical Care Medicine 2017 21(11):799-801Invasive monitoring with central venous catheter (CVC) is a valuable tool now a day in Intensive Care Units and in postoperative hemodynamically unstable patients. It is often employed for administering medications and parenteral nutrition. In most of the instances, these catheters are inserted using proper topographical landmarks and ultrasonography-guided methods. Central venous cannulation is associated now and then with unexpected complications despite the use of all precautions and help of imaging techniques. Ther...
Source: Indian Journal of Critical Care Medicine - November 13, 2017 Category: Intensive Care Authors: P Rajendra Takhar Bunkar Motilal Arya Savita Source Type: research

Methadone gastrobezoar in a psychiatric patient presented in coma
Alexandra Gavala, Despoina Manou, Vasiliki Psalida, Maria Nystatzaki, Christos Mavrogiannis, George Alevizopoulos, Pavlos MyrianthefsIndian Journal of Critical Care Medicine 2017 21(11):796-798A 43-year-old psychiatric patient was transferred in coma and hypercapnic respiratory failure at the emergency department. He was intubated for airway protection and transferred to the Intensive Care Unit (ICU). Abdominal X-ray revealed a radiopaque mass; a pharmacobezoar was suspected and confirmed by gastroscopy; one large in the stomach fundus and a smaller one in the pylorus. Gastric lavage through the gastroscope and administrat...
Source: Indian Journal of Critical Care Medicine - November 13, 2017 Category: Intensive Care Authors: Alexandra Gavala Despoina Manou Vasiliki Psalida Maria Nystatzaki Christos Mavrogiannis George Alevizopoulos Pavlos Myrianthefs Source Type: research

Canagliflozin-associated diabetic ketoacidosis with lower-than-anticipated glucose levels
Sonali Vadi, Manjusha AgarwalIndian Journal of Critical Care Medicine 2017 21(11):793-795The Food and Drug Administration has approved the use of sodium-glucose co-transporter 2 (SGLT-2) inhibitors for use in Type II diabetics. These are a relatively new addition to the armamentaria of diabetes management. Postmarketing surveillance is a witness to several side effects, a morbid one being ketoacidosis. Herein is discussed a scenario of a Type II diabetic who presented with substantial ketoacidosis without significant hyperglycemia. The absence of the customary precipitating factors and the presence of a recent introduction...
Source: Indian Journal of Critical Care Medicine - November 13, 2017 Category: Intensive Care Authors: Sonali Vadi Manjusha Agarwal Source Type: research

Meckel & #39;s diverticulitis masquerading as acute pancreatitis: A diagnostic dilemma
We report a 9-year-old boy who presented with acute onset of periumbilical pain and nonbilious vomiting. His clinical and laboratory parameters were unremarkable, except for serum amylase levels. He was conservatively managed initially as acute pancreatitis with paralytic ileus. However, the child deteriorated in a course of 2 days with bilious vomiting, abdominal distension, and dehydration. Imaging was suggestive of an ileoileal intussusception, and exploratory laparotomy identified Meckel's diverticulum as the lead point for the intussusception. The histopathological examination revealed inflamed heterotopic ...
Source: Indian Journal of Critical Care Medicine - November 13, 2017 Category: Intensive Care Authors: C Danny Darlington G Fatima Shirly Anitha Source Type: research

Imidacloprid poisoning: An emerging cause of potentially fatal poisoning
We report a case of poisoning with imidacloprid compound presenting with a variety of systemic features including respiratory failure and patient's improvement with conservative management. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - November 13, 2017 Category: Intensive Care Authors: Sanjay A Mundhe Siddheshwar V Birajdar Sheshrao S Chavan Nikhil R Pawar Source Type: research

Cerebral air embolism secondary to lung laceration
We report a case of cerebral air embolism which has occurred secondary to lung laceration. The patient underwent intercostal drainage for hydro-pneumothorax and developed forceful cough and suddenly changed in consciousness. Air embolism was diagnosed by computed tomography brain and was managed by high-concentration oxygen therapy and other supportive measures and is being discharged in satisfactory condition. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - November 13, 2017 Category: Intensive Care Authors: Ashok Kumar Singh Jayant Verma Surendra Kumar Source Type: research

Effect of intensive education and training of nurses on ventilator-associated pneumonia and central line-associated bloodstream infection incidence in intensive care unit at a tertiary care center in North India
Conclusion: Intensive education and training sessions with feedback from nurses over a period of 6 months led to significant reduction in the incidence of CLABSI; however, the incidence of VAP increased. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - November 13, 2017 Category: Intensive Care Authors: Neeru Sahni Manisha Biswal Komal Gandhi Kulbeer Kaur Vikas Saini Lakshminarayana N Yaddanapudi Source Type: research

Posterior reversible leukoencephalopathy syndrome (PRES) in intensive care unit & #8211; Case series
Conclusion: Irrespective of the etiology, early control of blood pressure, and removal of precipitating factors is of paramount importance to prevent morbidity and mortality. Awareness about PRES among the intensivist is necessary to ensure early recognition and treatment. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - November 13, 2017 Category: Intensive Care Authors: Antara Gokhale Atheel Kimona Sandeep Kantor S Prakash Yogesh Manhas Source Type: research

Prophylaxis and incidence of symptomatic deep vein thrombosis in indian patients with sepsis: DETECT-deep vein thrombosis registry
Conclusions: Two-third patients received thromboprophylaxis. The substantial role of thromboprophylaxis in DVT prevention mandates monitoring and control of thromboprophylaxis through internal audits in hospitals. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - November 13, 2017 Category: Intensive Care Authors: Nagarajan Ramakrishnan DETECT-DVT Investigators Source Type: research