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Colistin versus colistin combined with ampicillin-sulbactam for multiresistant Acinetobacter baumannii ventilator-associated pneumonia treatment: An open-label prospective study
Conclusion: Combination therapy with colistin and a high dose of ampicillin/sulbactam was associated with a more favorable clinical response to VAP due to carbapenem-resistant A. baumannii than colistin monotherapy. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - February 19, 2018 Category: Intensive Care Authors: Demosthenes Makris Efi Petinaki Vasssiliki Tsolaki Efstratios Manoulakas Konstantinos Mantzarlis Olimpia Apostolopoulou Dimitrios Sfyras Epaminondas Zakynthinos Source Type: research

Profile of patients with active tuberculosis admitted to a respiratory intensive care unit in a tertiary care center of North India
Conclusion: TB was an uncommon cause of ICU admission even in a high TB burden country. Critically ill patients with TB had high mortality. A higher APACHE II score and delta SOFA were independent predictors of ICU mortality. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - February 19, 2018 Category: Intensive Care Authors: Valliappan Muthu Sahajal Dhooria Ritesh Agarwal Kuruswamy Thurai Prasad Ashutosh N Aggarwal Digambar Behera Inderpaul Singh Sehgal Source Type: research

Quiz
Yash JaveriIndian Journal of Critical Care Medicine 2018 22(1):58-58 (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - January 15, 2018 Category: Intensive Care Authors: Yash Javeri Source Type: research

Epidemiology and antifungal susceptibility of Candida species isolated from urinary tract infections: A study from an intensive care unit of a tertiary care hospital
Priya Datta, Mandeep Kaur, Satinder Gombar, Jagdish ChanderIndian Journal of Critical Care Medicine 2018 22(1):56-57 (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - January 15, 2018 Category: Intensive Care Authors: Priya Datta Mandeep Kaur Satinder Gombar Jagdish Chander Source Type: research

Heart rate variability in children following drowning injury
Madhuradhar Chegondi, Jun Sasaki, Sayed Naqvi, Wei-Chiang Lin, Andre Raszynski, Balagangadhar R TotapallyIndian Journal of Critical Care Medicine 2018 22(1):53-55Heart rate variability (HRV) has been used as prognostic tool in various disorders in pediatric and adult patients. In our study we aimed to evaluate heart rate variability indices and their association with neurological outcome in three children with anoxic brain injury following drowning. Three children included in the study were admitted following drowning and required mechanical ventilation and targeted temperature management. All physiologic data, including e...
Source: Indian Journal of Critical Care Medicine - January 15, 2018 Category: Intensive Care Authors: Madhuradhar Chegondi Jun Sasaki Sayed Naqvi Wei-Chiang Lin Andre Raszynski Balagangadhar R Totapally Source Type: research

Phlegmasia cerulea dolens following heparin-induced thrombocytopenia
Deepesh G Aggarwal, Shilpa S Bhojraj, Ali Asgar Behrainwalla, Charu K Jani, Simin S MehtaIndian Journal of Critical Care Medicine 2018 22(1):51-52The authors present a case of a 49-year-old woman who underwent coronary artery bypass grafting after suffering from an acute coronary syndrome and later developed phlegmasia cerulea dolens with heparin-induced thrombocytopenia (HIT) and HIT thrombosis (HITT). (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - January 15, 2018 Category: Intensive Care Authors: Deepesh G Aggarwal Shilpa S Bhojraj Ali Asgar Behrainwalla Charu K Jani Simin S Mehta Source Type: research

Successful use of ketamine for burst suppression in super refractory status epilepticus following substance abuse
Dnyaneshwar P Mutkule, S Manimala Rao, Jaydip Ray Chaudhuri, Kunche RajasriIndian Journal of Critical Care Medicine 2018 22(1):49-50Status epilepticus is frequently encountered in neuro Intensive Care Units. It is a medical emergency and if not treated promptly can lead to severe brain damage and even death. Here, we present the case of a 18-year-old male with uncontrolled and unrelenting seizures with a rare etiology requiring ketamine infusion for burst suppression as it was resistant to thiopentone and midazolam infusions. The management of this case is presented in detail. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - January 15, 2018 Category: Intensive Care Authors: Dnyaneshwar P Mutkule S Manimala Rao Jaydip Ray Chaudhuri Kunche Rajasri Source Type: research

Cardiotoxic effects of raw opium
Piyush Garg, Asif Ali Hitawala, Manoj AgarwalIndian Journal of Critical Care Medicine 2018 22(1):46-48While opioid drug toxicity and side effects of long-term opioid use during medical care are well studied, there is little information regarding effects of ingestion of raw opium. Characterization of the effects to a particular alkaloid is difficult since raw opium contains a number of alkaloids. Here, we present a case of poisoning due to ingestion of raw opium leading to severe myocardial suppression. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - January 15, 2018 Category: Intensive Care Authors: Piyush Garg Asif Ali Hitawala Manoj Agarwal Source Type: research

Quad fever: Treatment through lowering of ambient temperature
We present a brief review of literature and the importance of early identification and treatment of this potentially fatal condition. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - January 15, 2018 Category: Intensive Care Authors: Shyam Sundar Krishnan Pulak Nigam Omar Bachh Madabushi Chakravarthy Vasudevan Source Type: research

An interesting presentation of pheochromocytoma
We present a case of a 41-year-old male patient who presented with cerebellar infarct and found to have aortic thrombi and later developed acute myocardial infaction during same hospitalization. To the best of our knowledge, this is the first reported case of this kind. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - January 15, 2018 Category: Intensive Care Authors: Sunil Kumar Garg Pragya Garg Mehmet Urumdas Source Type: research

Role of correction factor in minimizing errors while calculating electrolyte values between Blood & #8211;gas analyzer and laboratory autoanalyzer: A comparative study
Conclusion: The instrument type and calibration methods differ in different hospitals, so it is important that each center conducts an in-hospital study to know the correction factor before installation of an ABG, and the factor should be used accordingly to minimize all errors. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - January 15, 2018 Category: Intensive Care Authors: Abhinav Banerjee Gesu Mehrotra Source Type: research

Acute renal failure adversely affects survival in pediatric dengue infection
Conclusions: DHF/DSS is an independent risk factor for the development of ARF in patients with dengue infection. Mortality rate is high once RF develops in these children. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - January 15, 2018 Category: Intensive Care Authors: Biswanath Basu Birendranath Roy Source Type: research

Outcome of patients admitted to a tertiary referral intensive care unit with urosepsis needing source control
Conclusion: With early source control, obstructive UTI outcomes were comparable to nonobstructive UTI. However, despite undergoing ureteric stenting, more patients with obstructive UTI required RRT than those with nonobstructive UTI. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - January 15, 2018 Category: Intensive Care Authors: Chaitra C Rao Pradeep Rangappa Karthik Rao Ipe Jacob Source Type: research

Multicenter observational study to evaluate epidemiology and resistance patterns of common intensive care unit-infections
Conclusion: VAP is the most common infection followed by CRBSI and CAUTI. Multidrug-resistant Gram-negative bacteria are the most common organisms. Staphylococcus aureus is uncommon in the Indian setting. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - January 15, 2018 Category: Intensive Care Authors: Ramesh Venkataraman Jigi Divatia Nagarajan Ramakrishnan Rajesh Chawla Pravin Amin Palepu Gopal Dhruva Chaudhry Kapil Zirpe Babu Abraham Source Type: research

Pattern and outcome of obstetric admissions into the intensive care unit of a Southeast Nigerian Hospital
Conclusion: Ruptured uterus was the most common indication for ICU admission in the center. Maternal mortality was significantly associated with unbooked status. This underscores the importance of booking for antenatal care, prompt presentation at the hospital during emergencies, skilled birth attendance, and provision of adequate facilities for the management of critical obstetric cases in this environment. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - January 15, 2018 Category: Intensive Care Authors: Benjamin Chukwuma Ozumba Leonard Ogbonna Ajah Vitus Okwuchukwu Obi Uche Anthony Umeh Joseph Tochukwu Enebe Kingsley Chukwu Obioha Source Type: research