Successful Treatment With Ledipasvir/Sofosbuvir in an Infant With Severe Combined Immunodeficiency Caused by Adenosine Deaminase Deficiency With HCV Allowed Gene Therapy with Strimvelis
Hepatology, EarlyView. (Source: Hepatology)
Source: Hepatology - November 13, 2018 Category: Internal Medicine Authors: Francesca Tucci,
Valeria Calbi,
Federica Barzaghi,
Maddalena Migliavacca,
Francesca Ferrua,
Maria Ester Bernardo,
Daniele Canarutto,
Giulia Consiglieri,
Salvatore Recupero,
Francesco Calzatini,
Michela Gabaldo,
Caterina Lucano,
Miriam Casiragh Tags: Clinical Observations in Hepatology Source Type: research
Of Mice and Men and Nonalcoholic Steatohepatitis
Hepatology, EarlyView. (Source: Hepatology)
Source: Hepatology - November 13, 2018 Category: Internal Medicine Authors: David A. Brenner Tags: EDITORIAL Source Type: research
Revisiting the paradox of interferon ‐stimulated gene expression as a predictor of hepatitis C virus treatment response, a decade later
Hepatology, EarlyView. (Source: Hepatology)
Source: Hepatology - November 13, 2018 Category: Internal Medicine Authors: Lucy Golden ‐Mason,
Hugo R. Rosen Tags: Editorial Source Type: research
Successful Treatment With Ledipasvir/Sofosbuvir in an Infant With Severe Combined Immunodeficiency Caused by Adenosine Deaminase Deficiency With HCV Allowed Gene Therapy with Strimvelis
Hepatology, EarlyView. (Source: Hepatology)
Source: Hepatology - November 13, 2018 Category: Internal Medicine Authors: Francesca Tucci,
Valeria Calbi,
Federica Barzaghi,
Maddalena Migliavacca,
Francesca Ferrua,
Maria Ester Bernardo,
Daniele Canarutto,
Giulia Consiglieri,
Salvatore Recupero,
Francesco Calzatini,
Michela Gabaldo,
Caterina Lucano,
Miriam Casiragh Tags: Clinical Observations in Hepatology Source Type: research
Of Mice and Men and Nonalcoholic Steatohepatitis
Hepatology, EarlyView. (Source: Hepatology)
Source: Hepatology - November 13, 2018 Category: Internal Medicine Authors: David A. Brenner Tags: EDITORIAL Source Type: research
Revisiting the paradox of interferon ‐stimulated gene expression as a predictor of hepatitis C virus treatment response, a decade later
Hepatology, EarlyView. (Source: Hepatology)
Source: Hepatology - November 13, 2018 Category: Internal Medicine Authors: Lucy Golden ‐Mason,
Hugo R. Rosen Tags: Editorial Source Type: research
Liver Stiffness Measurements in Patients with Noncirrhotic Portal Hypertension —The Devil Is in the Details
Noncirrhotic portal hypertension (NCPH) is often a diagnostic challenge due to signs and symptoms of portal hypertension that overlap with cirrhosis. The etiology of NCPH is broadly classified as prehepatic, hepatic (presinusoidal and sinusoidal) and posthepatic.#hep30167-bib-0001 Some common etiologies of NCPH encountered in clinical practice include portal vein thrombosis (prehepatic) and nodular regenerative hyperplasia (hepatic). Liver histology, although considered gold standard to exclude cirrhosis in individuals with suspected NCPH, is often limited by subtle histologic features or inadequate sampling. Liver stiffne...
Source: Hepatology - November 12, 2018 Category: Internal Medicine Authors: Raj Vuppalanchi,
Karan Mathur,
Maximillian Pyko,
Niharika Samala,
Naga Chalasani Tags: Clinical Observations in Hepatology Source Type: research
Prospective Intraindividual Comparison of Magnetic Resonance Imaging With Gadoxetic Acid and Extracellular Contrast for Diagnosis of Hepatocellular Carcinomas Using the Liver Imaging Reporting and Data System
Conclusion: ECA ‐MRI showed better sensitivity and accuracy than HBA‐MRI for the diagnosis of HCC with LI‐RADS. We achieved better diagnostic performance when applying a modified washout on PVP/TP HBA‐MRI and an illusional washout on ECA‐MRI than we did with conventional criteria. (Source: Hepatology)
Source: Hepatology - November 12, 2018 Category: Internal Medicine Authors: Ji Hye Min,
Jong Man Kim,
Young Kon Kim,
Tae Wook Kang,
Soon Jin Lee,
Gyu Seong Choi,
Seo ‐Youn Choi,
Soohyun Ahn Tags: Original Article Source Type: research
Liver Stiffness Measurements in Patients with Noncirrhotic Portal Hypertension —The Devil Is in the Details
Noncirrhotic portal hypertension (NCPH) is often a diagnostic challenge due to signs and symptoms of portal hypertension that overlap with cirrhosis. The etiology of NCPH is broadly classified as prehepatic, hepatic (presinusoidal and sinusoidal) and posthepatic.#hep30167-bib-0001 Some common etiologies of NCPH encountered in clinical practice include portal vein thrombosis (prehepatic) and nodular regenerative hyperplasia (hepatic). Liver histology, although considered gold standard to exclude cirrhosis in individuals with suspected NCPH, is often limited by subtle histologic features or inadequate sampling. Liver stiffne...
Source: Hepatology - November 12, 2018 Category: Internal Medicine Authors: Raj Vuppalanchi,
Karan Mathur,
Maximillian Pyko,
Niharika Samala,
Naga Chalasani Tags: Clinical Observations in Hepatology Source Type: research
Prospective Intraindividual Comparison of Magnetic Resonance Imaging With Gadoxetic Acid and Extracellular Contrast for Diagnosis of Hepatocellular Carcinomas Using the Liver Imaging Reporting and Data System
Conclusion: ECA ‐MRI showed better sensitivity and accuracy than HBA‐MRI for the diagnosis of HCC with LI‐RADS. We achieved better diagnostic performance when applying a modified washout on PVP/TP HBA‐MRI and an illusional washout on ECA‐MRI than we did with conventional criteria. (Source: Hepatology)
Source: Hepatology - November 12, 2018 Category: Internal Medicine Authors: Ji Hye Min,
Jong Man Kim,
Young Kon Kim,
Tae Wook Kang,
Soon Jin Lee,
Gyu Seong Choi,
Seo ‐Youn Choi,
Soohyun Ahn Tags: Original Article Source Type: research
HSD17B13 is a Hepatic Retinol Dehydrogenase Associated with Histological Features of Non ‐Alcoholic Fatty Liver Disease
In conclusion, we demonstrate the association of variants inHSD17B13 with specific features of NAFLD histology, and identify the enzyme as a lipid droplet ‐associated RDH. Our data suggest that HSD17B13 plays a role in NAFLD through its enzymatic activity.This article is protected by copyright. All rights reserved. (Source: Hepatology)
Source: Hepatology - November 11, 2018 Category: Internal Medicine Authors: Yanling Ma,
Olga V. Belyaeva,
Philip M. Brown,
Koji Fujita,
Katherine Valles,
Suman Karki,
Ynto S. de Boer,
Christopher Koh,
Yanhua Chen,
Xiaomeng Du,
Samuel K. Handelman,
Vincent Chen,
Elizabeth K. Speliotes,
Cara Nestlerode,
Emmanuel Thoma Tags: Original Source Type: research
Intestinal immune dysregulation driven by dysbiosis promotes barrier disruption and bacterial translocation in rats with cirrhosis
Conclusion: The intestinal mucosa of rats with cirrhosis acquires a proinflammatory profile of immune dysregulation that parallels the severity of cirrhosis. This impaired intestinal immune response is driven by gut dysbiosis and leads to disrupted barrier function, promoting GBT.This article is protected by copyright. All rights reserved. (Source: Hepatology)
Source: Hepatology - November 10, 2018 Category: Internal Medicine Authors: Leticia Mu ñoz,
María‐José Borrero,
María Úbeda,
Elisa Conde,
Rosa del Campo,
Macarena Rodríguez‐Serrano,
Margaret Lario,
Ana‐María Sánchez‐Díaz,
Oscar Pastor,
David Díaz,
Laura García‐Bermejo,
Jorge Monserrat,
Melchor Ál Tags: Original Source Type: research
