HSD17B13 is a Hepatic Retinol Dehydrogenase Associated with Histological Features of Non ‐Alcoholic Fatty Liver Disease

In conclusion, we demonstrate the association of variants inHSD17B13 with specific features of NAFLD histology, and identify the enzyme as a lipid droplet ‐associated RDH. Our data suggest that HSD17B13 plays a role in NAFLD through its enzymatic activity.This article is protected by copyright. All rights reserved.

Source: Hepatology - November 11, 2018 Category: Internal Medicine Authors: Yanling Ma, Olga V. Belyaeva, Philip M. Brown, Koji Fujita, Katherine Valles, Suman Karki, Ynto S. de Boer, Christopher Koh, Yanhua Chen, Xiaomeng Du, Samuel K. Handelman, Vincent Chen, Elizabeth K. Speliotes, Cara Nestlerode, Emmanuel Thoma Tags: Original Source Type: research