ACR Appropriateness Criteria®-Anal Cancer.
Authors: Expert Panel on Radiation Oncology–Rectal/Anal Cancer, Hong TS, Pretz JL, Herman JM, Abdel-Wahab M, Azad N, Blackstock AW, Das P, Goodman KA, Jabbour SK, Jones WE, Konski AA, Koong AC, Rodriguez-Bigas M, Small W, Thomas CR, Zook J, Suh WW
Abstract
The management of anal cancer is driven by randomized and nonrandomized clinical trials. However, trials may present conflicting conclusions. Furthermore, different clinical situations may not be addressed in certain trials because of eligibility inclusion criteria. Although prospective studies point to the use of definitive 5-fluorouracil and mitomyci...
Source: Gastrointestinal Cancer Research - June 4, 2015 Category: Cancer & Oncology Tags: Gastrointest Cancer Res Source Type: research
Accelerated fraction radiotherapy with capecitabine as neoadjuvant therapy for borderline resectable pancreatic cancer.
CONCLUSIONS: Given the limited efficacy signal and severe gastric ulcerations, we do not recommend this regimen for pancreatic cancer. We also do not recommend the use of high doses per fraction outside a clinical trial.
PMID: 24558510 [PubMed] (Source: Gastrointestinal Cancer Research)
Source: Gastrointestinal Cancer Research - June 4, 2015 Category: Cancer & Oncology Tags: Gastrointest Cancer Res Source Type: research
KRAS G13D Mutation and Sensitivity to Cetuximab or Panitumumab in a Colorectal Cancer Cell Line Model.
CONCLUSION: The specific KRAS mutation determines the responsiveness to anti-EGFR monoclonal antibody treatment, corresponding to reported clinical observations.
PMID: 24558511 [PubMed] (Source: Gastrointestinal Cancer Research)
Source: Gastrointestinal Cancer Research - June 4, 2015 Category: Cancer & Oncology Tags: Gastrointest Cancer Res Source Type: research
A woman with metastatic pancreatic neuroendocrine tumor.
Authors: Shoushtari AN, Covey AM, Zaatari G, Shamseddine A, Epstein AS, Haydar A, Naghy M, Mukherji D, Kelsen DP, Abou-Alfa GK, O'Reilly EM
PMID: 24558512 [PubMed] (Source: Gastrointestinal Cancer Research)
Source: Gastrointestinal Cancer Research - June 4, 2015 Category: Cancer & Oncology Tags: Gastrointest Cancer Res Source Type: research
Tumor rupture as the initial manifestation of primary hepatic leiomyosarcoma.
Authors: Majumder S, Dedania B, Rezaizadeh H, Joyal T, Einstein M
PMID: 24558513 [PubMed] (Source: Gastrointestinal Cancer Research)
Source: Gastrointestinal Cancer Research - June 4, 2015 Category: Cancer & Oncology Tags: Gastrointest Cancer Res Source Type: research
Information for contributors.
Authors:
PMID: 24558514 [PubMed] (Source: Gastrointestinal Cancer Research)
Source: Gastrointestinal Cancer Research - June 4, 2015 Category: Cancer & Oncology Tags: Gastrointest Cancer Res Source Type: research
Upcoming articles.
Authors:
PMID: 24558515 [PubMed] (Source: Gastrointestinal Cancer Research)
Source: Gastrointestinal Cancer Research - June 4, 2015 Category: Cancer & Oncology Tags: Gastrointest Cancer Res Source Type: research
Absence of anaplastic lymphoma kinase translocations in signet ring cell carcinomas of the upper gastrointestinal tract.
CONCLUSIONS: These data indicate that, despite histologic similarities between SRCC of the upper GI tract and ALK-positive NSCLC, ALK translocations are unlikely to be a significant contributor to the molecular etiology of SRCC. Further genomic investigations are ongoing.
PMID: 24799969 [PubMed] (Source: Gastrointestinal Cancer Research)
Source: Gastrointestinal Cancer Research - June 4, 2015 Category: Cancer & Oncology Tags: Gastrointest Cancer Res Source Type: research
Overexpression of the HER2/neu Gene: A New Therapeutic Possibility for Patients With Advanced Gallbladder Cancer.
CONCLUSION: This is the single largest study of HER2/neu expression in gallbladder cancer to use commonly accepted scoring criteria. The results indicate that HER2/neu overexpression occurred in 14% of the advanced gallbladder cancer cases. This subgroup may benefit from inhibitors of the HER2/neu pathway.
PMID: 24799970 [PubMed] (Source: Gastrointestinal Cancer Research)
Source: Gastrointestinal Cancer Research - June 4, 2015 Category: Cancer & Oncology Tags: Gastrointest Cancer Res Source Type: research
Prognosis of Patients With Fibrolamellar Hepatocellular Carcinoma Versus Conventional Hepatocellular Carcinoma: A Systematic Review and Meta-analysis.
CONCLUSION: Patients with FL-HCC treated with hepatic resection had significantly higher 5-year survival rates than did those with NFL-HCC. However, survival was similar for both FL-HCC and conventional HCC in noncirrhotic patients. There seems to be no difference in survival outcomes for FL- and NFL-HCC when transplantation is used as the therapeutic option.
PMID: 24799971 [PubMed] (Source: Gastrointestinal Cancer Research)
Source: Gastrointestinal Cancer Research - June 4, 2015 Category: Cancer & Oncology Tags: Gastrointest Cancer Res Source Type: research
A 39-year-old female patient with metastatic rectal cancer develops thrombocytopenia.
Authors: Dbouk H, Mentha S, Mukherji D, Lee J, Haydar A, Shamseddine A, O'Reilly EM, Saltz L, Abou-Alfa GK
PMID: 24799972 [PubMed] (Source: Gastrointestinal Cancer Research)
Source: Gastrointestinal Cancer Research - June 4, 2015 Category: Cancer & Oncology Tags: Gastrointest Cancer Res Source Type: research
Acute gout episodes during treatment with capecitabine: a case report.
Authors: Peixoto RD, Cossetti R, Lim H, Cheung WY, Kennecke H
PMID: 24799973 [PubMed] (Source: Gastrointestinal Cancer Research)
Source: Gastrointestinal Cancer Research - June 4, 2015 Category: Cancer & Oncology Tags: Gastrointest Cancer Res Source Type: research
Metastatic non-small-cell lung cancer to the liver and pancreas.
Authors: Matt L, Sehgal R
PMID: 24799974 [PubMed] (Source: Gastrointestinal Cancer Research)
Source: Gastrointestinal Cancer Research - June 4, 2015 Category: Cancer & Oncology Tags: Gastrointest Cancer Res Source Type: research
Littoral cell angioma: gastrointestinal associations.
Authors: Sarandria JJ, Escano M, Kamangar F, Farooqui SO, Montgomery E, Cunningham SC
PMID: 24799975 [PubMed] (Source: Gastrointestinal Cancer Research)
Source: Gastrointestinal Cancer Research - June 4, 2015 Category: Cancer & Oncology Tags: Gastrointest Cancer Res Source Type: research
Definitive chemoradiation in oligometastatic squamous cell carcinoma of the anal canal.
Authors: Rogers JE, Crane CH, Das P, Delclos M, Gould MS, Ohinata A, Malatek D, Eng C
PMID: 24799976 [PubMed] (Source: Gastrointestinal Cancer Research)
Source: Gastrointestinal Cancer Research - June 4, 2015 Category: Cancer & Oncology Tags: Gastrointest Cancer Res Source Type: research
