Robot-assisted gait training versus treadmill training in patients with Parkinson's disease: a kinematic evaluation with gait profile score.
Authors: Galli M, Cimolin V, De Pandis MF, Le Pera D, Sova I, Albertini G, Stocchi F, Franceschini M Abstract The purpose of this study was to quantitatively compare the effects, on walking performance, of end-effector robotic rehabilitation locomotor training versus intensive training with a treadmill in Parkinson's disease (PD). Fifty patients with PD were randomly divided into two groups: 25 were assigned to the robot-assisted therapy group (RG) and 25 to the intensive treadmill therapy group (IG). They were evaluated with clinical examination and 3D quantitative gait analysis [gait profile score (GPS) ...
Source: Functional Neurology - October 1, 2016 Category: Neurology Tags: Funct Neurol Source Type: research

Frailty and resilience in an older population. The role of resilience during rehabilitation after orthopedic surgery in geriatric patients with multiple comorbidities.
Authors: Rebagliati GA, Sciumè L, Iannello P, Mottini A, Antonietti A, Caserta VA, Gattoronchieri V, Panella L, Callegari C Abstract Hip fracture is common in the elderly and it is usually associated with comorbidities and physiological changes which may have an impact on functioning and quality of life. The concept of resilience may explain why this impact varies among patients. The aim of this open, prospective cohort study was to explore the relationships between resilience, frailty and quality of life in orthopedic rehabilitation patients, and also to assess whether these factors might affect rehabili...
Source: Functional Neurology - October 1, 2016 Category: Neurology Tags: Funct Neurol Source Type: research

Post-stroke spasticity as a condition: a new perspective on patient evaluation.
Authors: Baricich A, Picelli A, Molteni F, Guanziroli E, Santamato A PMID: 27678212 [PubMed - in process] (Source: Functional Neurology)
Source: Functional Neurology - October 1, 2016 Category: Neurology Tags: Funct Neurol Source Type: research

What is cluster headache? Fact sheet for patients and their families. A publication to mark Cluster Headache Day 2016.
Authors: Rossi P, Whelan J, Craven A, Ruiz De La Torre E PMID: 27678213 [PubMed - in process] (Source: Functional Neurology)
Source: Functional Neurology - October 1, 2016 Category: Neurology Tags: Funct Neurol Source Type: research

Incidence and predictors of stroke during the index event in an ethnically diverse Takotsubo cardiomyopathy population.
Authors: Dias A, Franco E, Janzer S, Koshkelashvili N, Bhalla V, Rubio M, Amanullah S, Hebert K, Figueredo VM Abstract Takotsubo cardiomyopathy (TTS) is a peculiar clinical condition often affecting postmenopausal women after a stressful trigger. The underlying mechanisms have not been completely elucidated but several hypotheses have been advanced, with catecholamine cardiotoxicity, microvascular dysfunction and coronary artery spasm each suggested to play a role. The incidence of stroke after TTS appears to range from 0% to 7.7%, and interestingly TTS has been described as both a cause and a complication...
Source: Functional Neurology - September 27, 2016 Category: Neurology Tags: Funct Neurol Source Type: research

Clinical and genetic investigation of a Brazilian family with Huntington's disease.
Authors: Agostinho LA, Spitz M, Pereira JS, Paiva CL Abstract The aim of this study was to investigate a Brazilian family carrying full penetrance alleles for Huntington's disease (HD) in order to correlate each member's genetic and clinical features. To this end, the following scales were administered in each patient: the Beck Depression Inventory, the Mini-Mental State Examination (MMSE) and the Unified Huntington's Disease Rating Scale (UHDRS). The patterns of CAG and CCG polymorphic regions in the HTT gene were determined, the disease burden score was calculated, and genotypes were correlated with phen...
Source: Functional Neurology - August 20, 2016 Category: Neurology Tags: Funct Neurol Source Type: research

Women with epilepsy: clinically relevant issues.
Authors: Bangar S, Shastri A, El-Sayeh H, Cavanna AE Abstract Women with epilepsy (WWE) face specific challenges throughout their lifespan due to the effects of seizures and antiepileptic drugs on hormonal function, potentially affecting both sexual and reproductive health. This review article addresses the most common issues of practical relevance to clinicians treating WWE: epidemiology and clinical presentations (including catamenial epilepsy), contraception, reproductive and sexual dysfunction, pregnancy, lactation, menopause-related issues (including bone health), and mental health aspects. Awareness ...
Source: Functional Neurology - July 21, 2016 Category: Neurology Tags: Funct Neurol Source Type: research

Spectrum of cognitive disorders in idiopathic normal pressure hydrocephalus.
Authors: Picascia M, Minafra B, Zangaglia R, Gracardi L, Pozzi NG, Sinforiani E, Pacchetti C Abstract Idiopathic normal pressure hydrocephalus (iNPH) is a syndrome characterized by ventricular dilation accompanied by a progressive triad of a gait disturbance, "dementia" and incontinence. We retrospectively evaluated cognitive profile, and its relationship with disease variables, in 64 iNPH patients. The iNPH group performed significantly worse than the control group on all neuropsychological tests, except for verbal memory (within the normal range). The patients were subdivided into four groups: group 1 (4...
Source: Functional Neurology - July 21, 2016 Category: Neurology Tags: Funct Neurol Source Type: research

Robot-assisted gait training versus treadmill training in patients with Parkinson's disease: a kinematic evaluation with gait profile score.
Authors: Galli M, Cimolin V, De Pandis MF, Le Pera D, Sova I, Albertini G, Stocchi F, Franceschini M Abstract The purpose of this study was to quantitatively compare the effects, on walking performance, of end-effector robotic rehabilitation locomotor training versus intensive training with a treadmill in Parkinson's disease (PD). Fifty patients with PD were randomly divided into two groups: 25 were assigned to the robot-assisted therapy group (RG) and 25 to the intensive treadmill therapy group (IG). They were evaluated with clinical examination and 3D quantitative gait analysis [gait profile score (GPS) ...
Source: Functional Neurology - July 21, 2016 Category: Neurology Tags: Funct Neurol Source Type: research

New test of odor pleasantness in Parkinson's disease.
This study shows that the NTOP is a valuable method within the complex array of olfactory screening tools used in PD. PMID: 27428291 [PubMed - as supplied by publisher] (Source: Functional Neurology)
Source: Functional Neurology - July 21, 2016 Category: Neurology Tags: Funct Neurol Source Type: research

The cerebral venous system in migraine: the not so innocent bystander?
Authors: Tassorelli C PMID: 27358217 [PubMed - in process] (Source: Functional Neurology)
Source: Functional Neurology - July 1, 2016 Category: Neurology Tags: Funct Neurol Source Type: research

Lower- and higher-level models of right hemisphere language. A selective survey.
Authors: Gainotti G Abstract The models advanced to explain right hemisphere (RH) language function can be divided into two main types. According to the older (lower-level) models, RH language reflects the ontogenesis of conceptual and semantic-lexical development; the more recent models, on the other hand, suggest that the RH plays an important role in the use of higher-level language functions, such as metaphors, to convey complex, abstract concepts. The hypothesis that the RH may be preferentially involved in processing the semantic-lexical components of language was advanced by Zaidel in splitbrain pat...
Source: Functional Neurology - July 1, 2016 Category: Neurology Tags: Funct Neurol Source Type: research

Vestibular disorders following different types of head and neck trauma.
Authors: Kolev OI, Sergeeva M Abstract This review focuses on the published literature on vestibular disorders following different types of head and neck trauma. Current knowledge of the different causes and underlying mechanisms of vestibular disorders, as well as the sites of organic damage, is presented. Non-organic mechanisms are also surveyed. The frequency of occurrence of vestibular symptoms, and of other accompanying subjective complaints, associated with different types of trauma is presented and related to the specific causes. Hypotheses about the pathogenesis of traumatic vestibular disorders ar...
Source: Functional Neurology - July 1, 2016 Category: Neurology Tags: Funct Neurol Source Type: research

Cerebral venous hemodynamic abnormalities in episodic and chronic migraine.
Authors: Petolicchio B, Viganò A, di Biase L, Tatulli D, Toscano M, Vicenzini E, Passarelli F, Di Piero V Abstract Alterations of cerebral venous drainage have been demonstrated in chronic migraine (CM), suggesting that cerebral venous hemodynamic abnormalities (CVHAs) play a role in this condition. The aim of the present study was to look for a correlation between CM and CVHAs. We recruited 33 subjects suffering from CM with or without analgesic overuse, 29 episodic migraine (EM) patients with or without aura, and 21 healthy subjects as controls (HCs). CVHAs were evaluated by transcranial and extracrania...
Source: Functional Neurology - July 1, 2016 Category: Neurology Tags: Funct Neurol Source Type: research

Antiepileptic drug use in a nursing home setting: a retrospective study in older adults.
Authors: Callegari C, Ielmini M, Bianchi L, Lucano M, Bertù L, Vender S Abstract The authors set out to examine qualitatively the use of antiepileptic drugs (AEDs) in a population of older adults in a nursing home setting, evaluating aspects such as specialist prescriptions and changes in dosage. This retrospective prevalence study was carried out in a state-funded nursing home that provides care and rehabilitation for elderly people. The first objective of the study was to determine the prevalence of AED use in this population. The second objective was to monitor AED dosage modifications during the fifte...
Source: Functional Neurology - July 1, 2016 Category: Neurology Tags: Funct Neurol Source Type: research