The EuPA Company Club – Status, report, developments and perspectives
Publication date: Available online 5 October 2014 Source:EuPA Open Proteomics Author(s): Peter Verhaert , Christian Kleinhammer (Source: EuPA Open Proteomics)
Source: EuPA Open Proteomics - October 13, 2014 Category: Bioinformatics Source Type: research
Human maternal plasma proteomic changes with parturition
Publication date: December 2014 Source:EuPA Open Proteomics, Volume 5 Author(s): Robert J. Phillips , Kate J. Heesom , Johanna Trinder , Andrés López Bernal The powerful proteomic technique of Tandem Mass Tag labelling with Orbitrap mass spectrometry was applied to the quantification of relative levels of proteins in serial plasma samples from 15 women prior to and during labour. Quantitative data were obtained for 1038 proteins, with 217 quantified in ≥10 sample pairs. Most proteins were unaffected by labour, 32 had lower levels in labour, and two were increased in labour, and the t test had sufficient power t...
Source: EuPA Open Proteomics - October 13, 2014 Category: Bioinformatics Source Type: research
Proteomic analysis of secreted proteins from skeletal muscle cells during differentiation
Publication date: December 2014 Source:EuPA Open Proteomics, Volume 5 Author(s): Koichi Ojima , Mika Oe , Ikuyo Nakajima , Masahiro Shibata , Koichi Chikuni , Susumu Muroya , Takanori Nishimura Myokines are muscle-secreted factors to regulate cellular functions. However, it remains elusive what type of myokine is released during muscle differentiation. Here we evaluated the dynamics of myokines. More than 400 proteins were detected in conditioned medium and approximately 8% of them were categorized as myokines. The levels of myokines which promote myotube formation, vascularization or neurogenesis peaked during ...
Source: EuPA Open Proteomics - October 13, 2014 Category: Bioinformatics Source Type: research
