Comparison of narrowband imaging with autofluorescence imaging for endoscopic visualization of superficial squamous cell carcinoma lesions of the esophagus.
Conclusion. NBI may be more effective than AFI for visualization of esophageal SCC. PMID: 23197931 [PubMed] (Source: Diagnostic and Therapeutic Endoscopy)
Source: Diagnostic and Therapeutic Endoscopy - June 5, 2015 Category: Surgery Tags: Diagn Ther Endosc Source Type: research

Contrast-enhanced harmonic endoscopic ultrasonography in pancreatic diseases.
Authors: Xu C, Li Z, Wallace M Abstract Endoscopic ultrasonography (EUS) is the most sensitive imaging method for diagnosis of pancreatic tumors. However, it still has limits in the differentiation between pancreatic cancers and inflammatory tumor-like masses. A novel technology, contrast-enhanced harmonic EUS (CH-EUS), has been developed recently. It can visualize both parenchymal perfusion and microvasculature in pancreas without Doppler-related artifacts. Therefore, it is superior to EUS and CT in detecting small pancreatic masses and differential diagnosis of pancreatic masses. CH-EUS could be used for...
Source: Diagnostic and Therapeutic Endoscopy - June 5, 2015 Category: Surgery Tags: Diagn Ther Endosc Source Type: research

Endoscopic color Doppler ultrasonography for esophagogastric varices.
Authors: Sato T, Yamazaki K Abstract Esophagogastric varices are considered to be the most common complication in patients with portal hypertension. Endoscopic ultrasonography not only visualizes the surface of the varices but also provides detailed information about their internal structure. The direction of blood flow can be determined and its velocity measured only via endoscopic color Doppler ultrasonography (ECDUS). This can show graphically esophageal varices, paraesophageal veins, and passageways in esophageal variceal patients and gastric varices, perigastric collateral veins in gastric variceal pa...
Source: Diagnostic and Therapeutic Endoscopy - June 5, 2015 Category: Surgery Tags: Diagn Ther Endosc Source Type: research

Use of i-scan Endoscopic Image Enhancement Technology in Clinical Practice to Assist in Diagnostic and Therapeutic Endoscopy: A Case Series and Review of the Literature.
Conclusions. i-scan imaging provides detailed topography of mucosal surfaces and delineates lesion edges, which can directly impact endoscopic management. PMID: 23243384 [PubMed] (Source: Diagnostic and Therapeutic Endoscopy)
Source: Diagnostic and Therapeutic Endoscopy - June 5, 2015 Category: Surgery Tags: Diagn Ther Endosc Source Type: research

The learning curve of gastric intestinal metaplasia interpretation on the images obtained by probe-based confocal laser endomicroscopy.
Conclusion. After a short session of training on GIM interpretation of pCLE images, the beginners can achieve a high level of reading accuracy with at least substantial level of interobserver agreement. Once they achieve the high reading accuracy, almost all can maintain their high quality of reading skill. PMID: 23243385 [PubMed] (Source: Diagnostic and Therapeutic Endoscopy)
Source: Diagnostic and Therapeutic Endoscopy - June 5, 2015 Category: Surgery Tags: Diagn Ther Endosc Source Type: research

Diagnosis of Early Gastric Cancer by Magnifying Endoscopy with NBI from Viewpoint of Histological Imaging: Mucosal Patterning in terms of White Zone Visibility and Its Relationship to Histology.
Authors: Yagi K, Nozawa Y, Endou S, Nakamura A Abstract THE DIAGNOSIS OF EARLY GASTRIC CANCER BY MAGNIFYING ENDOSCOPY WITH NBI IS BASED ON TWO COMPONENTS: microvascular pattern and mucosal pattern. Mucosal patterns are characterized by a whitish edge, which has been named the white zone. Some cancerous areas showing a distinct white zone form clear mucosal patterns, whereas others showing a nondistinct white zone do not form mucosal patterns. The aim of the present study was to clarify the histological differences between these two types of area. In transverse sections of gastric epithelium, the lengths of...
Source: Diagnostic and Therapeutic Endoscopy - June 5, 2015 Category: Surgery Tags: Diagn Ther Endosc Source Type: research

NBI and NBI Combined with Magnifying Colonoscopy.
Authors: Iwatate M, Ikumoto T, Hattori S, Sano W, Sano Y, Fujimori T Abstract Although magnifying chromoendoscopy had been a reliable diagnostic tool, narrow-band imaging (NBI) has been developed in Japan since 1999 and has now replaced the major role of chromoendoscopy because of its convenience and simplicity. In this paper, we principally describe the efficacy of magnifying chromoendoscopy and magnifying colonoscopy with NBI for detection, histological prediction, estimation of the depth of early colorectal cancer, and future prospects. Although some meta-analyses have concluded that NBI is not superior...
Source: Diagnostic and Therapeutic Endoscopy - June 5, 2015 Category: Surgery Tags: Diagn Ther Endosc Source Type: research

Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis in Pancreatic Cancer: A Prospective Pilot Study of Safety Using 10 mL versus 20 mL Alcohol.
Conclusions. EUS-CPN using 20 mL of alcohol is safe. Similar clinical outcomes were seen in both groups. Further investigations to confirm these findings are warranted. PMID: 23365492 [PubMed] (Source: Diagnostic and Therapeutic Endoscopy)
Source: Diagnostic and Therapeutic Endoscopy - June 5, 2015 Category: Surgery Tags: Diagn Ther Endosc Source Type: research

Endomicroscopic Imaging of COX-2 Activity in Murine Sporadic and Colitis-Associated Colorectal Cancer.
Authors: Foersch S, Neufert C, Neurath MF, Waldner MJ Abstract Although several studies propose a chemopreventive effect of aspirin for colorectal cancer (CRC) development, the general use of aspirin cannot be recommended due to its adverse side effects. As the protective effect of aspirin has been associated with an increased expression of COX-2, molecular imaging of COX-2, for instance, during confocal endomicroscopy could enable the identification of patients who would possibly benefit from aspirin treatment. In this pilot trial, we used a COX-2-specific fluorescent probe for detection of colitis-associ...
Source: Diagnostic and Therapeutic Endoscopy - June 5, 2015 Category: Surgery Tags: Diagn Ther Endosc Source Type: research

Narrow band imaging with magnification can pick up esophageal squamous cell carcinoma more efficiently than lugol chromoendoscopy in patients after chemoradiotherapy.
Conclusion. NBI with magnification would be able to pick up esophageal neoplasia more efficiently than Lugol chromoendoscopy in patients after chemoradiotherapy. PMID: 23476110 [PubMed] (Source: Diagnostic and Therapeutic Endoscopy)
Source: Diagnostic and Therapeutic Endoscopy - June 5, 2015 Category: Surgery Tags: Diagn Ther Endosc Source Type: research

Endomicroscopy of the pancreaticobiliary system.
Authors: Peter S, Bang JY, Mönkemuller K, Varardarajulu S, Wilcox CM Abstract It is often difficult to accurately differentiate between benign and malignant pancreaticobiliary strictures, and some are interpreted as indeterminate despite ERCP, EUS, or radiological imaging techniques, thereby making it difficult for the clinician to make appropriate management decisions. Probe-based confocal laser endomicroscopy (pCLE) is an innovative imaging tool integrating real-time in vivo imaging of these difficult-to-interpret strictures in the pancreaticobiliary system during endoscopy. Recent studies of endomicros...
Source: Diagnostic and Therapeutic Endoscopy - June 5, 2015 Category: Surgery Tags: Diagn Ther Endosc Source Type: research

Endoscopic ultrasound-guided oncologic therapy for pancreatic cancer.
Authors: Suzuki R, Irisawa A, Bhutani MS Abstract Since the development of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) in the early 1990s, its application has been extended to various diseases. For pancreatic cancer, EUS-FNA can obtain specimens from the tumor itself with fewer complications than other methods. Interventional EUS enables various therapeutic options: local ablation, brachytherapy, placement of fiducial markers for radiotherapy, and direct injection of antitumor agents into cancer. This paper will focus on EUS-guided oncologic therapy for pancreatic cancer. PMID: 23...
Source: Diagnostic and Therapeutic Endoscopy - June 5, 2015 Category: Surgery Tags: Diagn Ther Endosc Source Type: research

The current state of diagnosis and treatment for early gastric cancer.
Authors: Yada T, Yokoi C, Uemura N Abstract The prognosis for gastric cancer depends on its stage; so, detection in the early stage of disease is important, when complete and curative removal is possible. Accurate diagnosis can be facilitated by a sound understanding of the basic findings of white light endoscopy of early gastric cancer, and diagnosis can be refined further by the combined use of other imaging modalities such as image-enhanced endoscopy including chromoendoscopy and endoscopic ultrasonography. Minimally invasive endoscopic treatment has come to be the preferred therapeutic approach for ear...
Source: Diagnostic and Therapeutic Endoscopy - June 5, 2015 Category: Surgery Tags: Diagn Ther Endosc Source Type: research

Colonoscopy practice in lagos, Nigeria: a report of an audit.
Conclusion. Colonoscopy utilization is low, and the quality of practice is suboptimal; although limited resources could partly explain this, however it is not clear if the low rate of polyp detection is due to missed lesions or low population incidence. PMID: 23533321 [PubMed] (Source: Diagnostic and Therapeutic Endoscopy)
Source: Diagnostic and Therapeutic Endoscopy - June 5, 2015 Category: Surgery Tags: Diagn Ther Endosc Source Type: research

Efficacy, Safety, and Long-Term Follow-Up Results of EUS-Guided Transmural Drainage for Pancreatic Pseudocyst.
Conclusion. EUS-GTD is a relatively safe and effective therapeutic method. However, further analysis should be done by larger series to determine the method of EUS-GTD for pancreatic pseudocyst. PMID: 23554548 [PubMed] (Source: Diagnostic and Therapeutic Endoscopy)
Source: Diagnostic and Therapeutic Endoscopy - June 5, 2015 Category: Surgery Tags: Diagn Ther Endosc Source Type: research