Cardiovascular outcomes of pregnancy in Marfan's syndrome patients: A literature review
ConclusionsPatients with MFS, especially those whose initial aortic diameters ≥40 mm, planning a pregnancy or currently pregnant should be carefully counseled about the maternal and fetal risks throughout pregnancy. MFS patients whose aortic diameters ≥40 mm should be advised to ideally await pregnancy until prophylactic aortic surgery. As MFS varies in its phenotypic expression, each patient's risk of adverse cardiac events should be assessed individually through a joint Maternal Fetal Medicine and Cardiology Center. (Source: Congenital Heart Disease)
Source: Congenital Heart Disease - September 1, 2017 Category: Cardiology Authors: So Yeon Kim, Diana S. Wolfe, Cynthia C. Taub Tags: REVIEW ARTICLE Source Type: research
Epigenetics for the pediatric cardiologist
Abstract
A genetic basis of congenital heart disease (CHD) has been known for decades. In addition to the sequence of the genome, the contribution of epigenetics to pediatric cardiology is increasingly recognized. Multiple epigenetic mechanisms, including DNA methylation, histone modification, and RNA‐based regulation, are known mediators of cardiovascular disease, including both development and progression of CHD and its sequelae. Basic understanding of the concepts of epigenetics will be essential to all pediatric cardiologists in order to understand mechanisms of pathophysiology, pharmacotherapeutic concepts, and to u...
Source: Congenital Heart Disease - September 1, 2017 Category: Cardiology Authors: Andrew D. Spearman Tags: FELLOWS FORUM Source Type: research
Incidence and natural history of neonatal isolated ventricular septal defects: Do we know everything? A 6 ‐year single‐center Italian experience follow‐up
Congenital Heart Disease,Volume 13, Issue 1, Page 105-112, January/February 2018. (Source: Congenital Heart Disease)
Source: Congenital Heart Disease - August 30, 2017 Category: Cardiology Source Type: research
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Congenital Heart Disease,Volume 13, Issue 1, Page 105-112, January/February 2018. (Source: Congenital Heart Disease)
Source: Congenital Heart Disease - August 30, 2017 Category: Cardiology Source Type: research
Hemodynamic, biological, and right ventricular functional changes following intraatrial shunt repair in patients with flow ‐induced pulmonary hypertension
ConclusionsThe implantation of an occluder successfully improved hemodynamic, right ventricular, and daily performance. Qualitative enhancement of colony formation for endothelial progenitor cells was also noted and positively correlated with daily performance. Closure of defects may serve as a valid, reliable model to obtain a deeper understanding of the modulation of endothelial progenitor cell activity and its relationship with pulmonary hypertension prognosis. (Source: Congenital Heart Disease)
Source: Congenital Heart Disease - August 8, 2017 Category: Cardiology Authors: Chih ‐Hsin Hsu, Jun‐Neng Roan, Jieh‐Neng Wang, Chien‐Chi Huang, Chao‐Jung Shih, Jyh‐Hong Chen, Jing‐Ming Wu, Chen‐Fuh Lam Tags: ORIGINAL ARTICLE Source Type: research
