Early intensive therapy may delay MS progression
Early aggressive therapy for multiple sclerosis is associated with improved long-term outcomes compared with an escalation approach, a study in JAMA Neurology has shown. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - March 15, 2019 Category: Drugs & Pharmacology Source Type: research

High-risk HPV infection linked to increased risk of cardiovascular disease
Women with high-risk human papillomavirus infection are more likely to develop cardiovascular disease than those without, the results of a study published in Circulation Research suggest. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - March 11, 2019 Category: Drugs & Pharmacology Source Type: research

Impact of opioid prescribing following arthroplasty on long-term opioid prescribing in the community
Adequate relief of acute postsurgical pain is a metric of patient satisfaction[1]. Patients undergoing hip and knee arthroplasty — in which joints are altered or replaced — ... (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - March 8, 2019 Category: Drugs & Pharmacology Source Type: research

Exercise interventions reduce falls in older adults
The rate of falls in older adults living in the community can be effectively reduced with exercise interventions, the authors of a recent Cochrane review have concluded. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - March 8, 2019 Category: Drugs & Pharmacology Source Type: research

Managing the symptoms of overactive bladder
Overactive bladder can be distressing and embarrassing. Understanding the symptoms, diagnosis and evidence-based management can significantly improve quality of life. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - March 8, 2019 Category: Drugs & Pharmacology Source Type: research

How a breath biopsy test could change the face of early cancer detection
A pain-free 1 –10 minute breath sampler could enhance and speed up the early detection of a range of cancers, writes Balkees Abderrahman. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - March 7, 2019 Category: Drugs & Pharmacology Source Type: research

What could UK pharmacy teams learn about suicide prevention from North America?
This article examines the published evidence-base and the success of ongoing programmes and initiatives in the United States and Canada to  produce a set of recommendations for the benefit of UK practice on the opportunities community pharmacy teams have to raise awareness and help prevent suicide and self-harm. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - March 5, 2019 Category: Drugs & Pharmacology Source Type: research

Prodrug opioids less effective in patients on SSRIs
Direct acting, rather than prodrug, opioids should be considered for postoperative pain relief in patients with depression receiving selective serotonin reuptake inhibitors, researchers have found. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - March 4, 2019 Category: Drugs & Pharmacology Source Type: research

Enzyme mouth spray could shorten cold duration
An oral spray containing a proteolytic enzyme reduced the severity and duration of the common cold, a randomised study has found. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - March 1, 2019 Category: Drugs & Pharmacology Source Type: research

Using a gravimetric chemotherapy workflow system to improve care
Efficiency and patient safety can be improved throughout the drug management continuum. This communication describes an experience of a new intravenous workflow compounding system, BD Cato, in improving patient safety, process efficiency and regulatory compliance ... (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - February 27, 2019 Category: Drugs & Pharmacology Source Type: research

Preventing hazardous prescribing with a pharmacist-led dashboard intervention
Medication errors that lead to adverse drug events are a major problem, and one that has been acknowledged by the World Health Organization ’s third Global Patient Safety Challenge. In the UK, (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - February 25, 2019 Category: Drugs & Pharmacology Source Type: research

Needle and syringe programmes cost effective in reducing HCV transmission
Study shows needle and syringe programmes reduce transmission of hepatitis C while delivering  cost savings. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - February 22, 2019 Category: Drugs & Pharmacology Source Type: research

Long-term follow-up allays fears that finasteride increases mortality
Initial concerns that finasteride could increase risk of prostate cancer death have been found to be unwarranted in a long-term follow-up study. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - February 21, 2019 Category: Drugs & Pharmacology Source Type: research

Naltrexone not associated with serious adverse events, review finds
The opioid antagonist naltrexone does not appear to increase the risk of serious adverse events over placebo, researchers from the University of Manchester have found. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - February 18, 2019 Category: Drugs & Pharmacology Source Type: research

Study questions link between antidepressants and hip fractures
A previously identified link between antidepressant use and hip fractures needs further examination, the authors of a study published in JAMA Psychiatry have concluded. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - February 15, 2019 Category: Drugs & Pharmacology Source Type: research