Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Pneumocystis Pneumonia in Human Immunodeficiency Virus–infected Adults and Adolescents: Current Concepts and Future Directions
Pneumocystis jirovecii pneumonia (PCP) is one of the most common opportunistic infections in human immunodeficiency virus–infected adults. Colonization of Pneumocystis is highly prevalent among the general population and could be associated with the transmission and development of PCP in immunocompromised individuals. Although the microscopic demonstration of the organisms in respiratory specimens is still the golden standard of its diagnosis, polymerase chain reaction has been shown to have a high sensitivity, detecting Pneumocystis DNA in induced sputum or oropharyngeal wash. Serum β-D-glucan is useful as an adjunctiv...
Source: Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine - August 12, 2015 Category: Respiratory Medicine Authors: Sadatomo Tasaka Source Type: research

Recent Treatment of Interstitial Lung Disease with Idiopathic Inflammatory Myopathies
Interstitial lung disease (ILD) is a prognostic factor for poor outcome in polymyositis (PM)/dermatomyositis (DM). The appropriate management of ILD is very important to improve the prognosis of patients with PM/DM. ILD activity and severity depend on the disease subtype. Therefore, clinicians should determine therapeutic strategies according to the disease subtype in each patient with PM/DM. Anti–melanoma differentiation-associated gene 5 antibody and hyperferritinemia predict the development and severity of rapidly progressive (RP) ILD, particularly in East Asian patients. Combination therapy with corticosteroids, intr...
Source: Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine - July 23, 2015 Category: Respiratory Medicine Authors: Hidenaga KawasumiTakahisa GonoYasushi KawaguchiHisashi Yamanaka Source Type: research

Pulmonary Hypertension an Independent Risk Factor for Death in Intensive Care Unit: Correlation of Hemodynamic Factors with Mortality
Objective: Critically ill patients with pulmonary hypertension (PH) pose additional challenges due to the existence of right ventricular (RV) dysfunction. The purpose of this study was to assess the impact of hemodynamic factors on the outcome. Methods: We reviewed the records of patients with a diagnosis of PH admitted to the intensive care unit. In addition to evaluating traditional hemodynamic parameters, we defined severe PH as right atrial pressure >20 mmHg, mean pulmonary artery pressure >55 mmHg, or cardiac index (CI) (Source: Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine)
Source: Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine - June 23, 2015 Category: Respiratory Medicine Authors: Ghulam SaydainAamir AwanPalaniappan ManickamPaul KleinowSafwan Badr Source Type: research

Genetics of Interstitial Lung Disease: Vol de Nuit (Night Flight)
Interstitial lung disease (ILD) is a chronic, progressive fibrotic lung disease with a dismal prognosis. ILD of unknown etiology is referred to as idiopathic interstitial pneumonia (IIP), which is sporadic in the majority of cases. ILD is frequently accompanied by rheumatoid arthritis (RA), systemic sclerosis (SSc), polymyositis/dermatomyositis (PM/DM), and other autoimmune diseases, and is referred to as collagen vascular disease-associated ILD (CVD-ILD). Susceptibility to ILD is influenced by genetic and environmental factors. Recent advances in radiographic imaging techniques such as high-resolution computed tomography ...
Source: Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine - April 29, 2015 Category: Respiratory Medicine Authors: Hiroshi FurukawaShomi OkaKota ShimadaNaoyuki TsuchiyaShigeto Tohma Source Type: research

Normalization of Lung Function Following Treatment of Secondary Usual Interstitial Pneumonia: A Case Report
This report suggests that occasionally, patients with secondary UIP occurring in the context of otherwise undefinable autoimmune clinical syndromes may be responsive to immunosuppressive therapy. (Source: Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine)
Source: Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine - April 16, 2015 Category: Respiratory Medicine Authors: Laurie A. HohbergerFelicia Montero-AriasAnja C. RodenRobert Vassallo Source Type: research

Osteoporosis in Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a lifestyle-related chronic inflammatory pulmonary disease associated with significant morbidity and mortality worldwide. COPD is associated with various comorbidities found in all stages of COPD. The comorbidities have significant impact in terms of morbidity, mortality, and economic burden in COPD. Management of comorbidities should be incorporated into the comprehensive management of COPD as this will also have an effect on the outcome in COPD patients. Various comorbidities reported in COPD include cardiovascular disease, skeletal muscle dysfunction, anemia, metabolic syn...
Source: Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine - March 12, 2015 Category: Respiratory Medicine Authors: Malay SarkarRajeev BhardwajIrappa Madabhavi Jasmin Khatana Source Type: research

Klippel & ndash;Tr & eacute;naunay Syndrome & ndash; A Very Rare and Interesting Syndrome
We report a case of a 12-year-old male who presented to us with the symptoms of varicose plaques over both lower limbs and was diagnosed as a case of KTS. Management is normally conservative and includes stockings for compression of the branches to reduce edema because of chronic venous insufficiency; modern devices that cause on and off pneumatic compression; and rarely, surgical correction of varicose veins with lifelong follow-up. The orthopedic abnormalities are treated with epiphysiodesis in order to prevent (stop) overgrowing of limb and correction of bone deformity. (Source: Clinical Medicine Insights: Circulatory, ...
Source: Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine - March 5, 2015 Category: Respiratory Medicine Authors: Deepak Sharma Sachin Lamba Aakash Pandita Sweta Shastri Source Type: research

Klippel–Trénaunay Syndrome – A Very Rare and Interesting Syndrome
We report a case of a 12-year-old male who presented to us with the symptoms of varicose plaques over both lower limbs and was diagnosed as a case of KTS. Management is normally conservative and includes stockings for compression of the branches to reduce edema because of chronic venous insufficiency; modern devices that cause on and off pneumatic compression; and rarely, surgical correction of varicose veins with lifelong follow-up. The orthopedic abnormalities are treated with epiphysiodesis in order to prevent (stop) overgrowing of limb and correction of bone deformity. (Source: Clinical Medicine Insights: Circulatory, ...
Source: Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine - March 5, 2015 Category: Respiratory Medicine Authors: Deepak SharmaSachin LambaAakash PanditaSweta Shastri Source Type: research