Critical airways, critical language
British Journal of Anaesthesia, 2017; 118(5): 649 –54, DOI10.1093/bja/aex075 (Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - June 30, 2017 Category: Anesthesiology Source Type: research
Association of intraoperative changes in brain-derived neurotrophic factor and postoperative delirium in older adults
Conclusions. We observed an association between intraoperative decline in plasma BDNF and delirium. These preliminary results need to be confirmed but suggest that plasma BDNF levels may be a biomarker for postoperative delirium. (Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - June 30, 2017 Category: Anesthesiology Source Type: research
Predicting delirium: are we there yet?
Postoperative delirium is an extremely common complication after all types of surgery in the elderly, with an incidence as high as 65% in patients admitted for hip fracture repair.1 The implications of an episode of delirium are serious and include an increased risk of dementia, increased length of stay, increased costs, and increased risk of mortality.1 Delirium is associated with progression of cognitive decline even in those with normal baseline cognition.2 It is widely acknowledged that delirium is a preventable complication, with the Australian Council for Safety and Quality in Health Care (ACSQHC), the National Insti...
Source: British Journal of Anaesthesia - June 30, 2017 Category: Anesthesiology Source Type: research
Postoperative delirium in elderly patients is associated with subsequent cognitive impairment
Conclusions. Mild cognitive impairment or dementia is a risk for POD. Elderly patients who have not been diagnosed with MCI or dementia but experience POD are more likely to be diagnosed subsequently with MCI or dementia. (Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - June 28, 2017 Category: Anesthesiology Source Type: research
Intelligent dynamic clinical checklists improved checklist compliance in the intensive care unit
Conclusions. This simulation study indicates that an intelligent DCC significantly increases compliance with best practice by reducing the percentage of unchecked items during ICU ward rounds, while the user satisfaction rate remains high. Real-life clinical research is required to evaluate this new type of checklist further. (Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - June 28, 2017 Category: Anesthesiology Source Type: research
Predicting postoperative morbidity in adult elective surgical patients using the Surgical Outcome Risk Tool (SORT)
Conclusions. SORT-morbidity can be used before surgery, with clinical judgement, to predict postoperative morbidity risk in major elective surgery. (Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - June 28, 2017 Category: Anesthesiology Source Type: research
Elevated preoperative heart rate is associated with cardiopulmonary and autonomic impairment in high-risk surgical patients
Conclusions. Elevated preoperative heart rate is associated with impaired cardiopulmonary performance consistent with clinically unsuspected, subclinical cardiac failure.Clinical trial registration. ISRCTN88456378. (Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - June 28, 2017 Category: Anesthesiology Source Type: research
Association between preoperative pulse pressure and perioperative myocardial injury: an international observational cohort study of patients undergoing non-cardiac surgery
Conclusions. Preoperative pulse pressure>62 mm Hg was associated with myocardial injury, independent of systolic blood pressure. Elevated pulse pressure may be a useful clinical sign to guide strategies to reduce perioperative myocardial injury. (Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - June 28, 2017 Category: Anesthesiology Source Type: research
Post-induction hypotension and early intraoperative hypotension associated with general anaesthesia
Conclusions. We identified clinical factors associated with PIH and eIOH. The use of these factors to estimate the risk of PIH and eIOH might allow the avoidance or timely treatment of hypotensive episodes during general anaesthesia. (Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - June 28, 2017 Category: Anesthesiology Source Type: research
Predictor of fluid responsiveness in the ‘grey zone’: augmented pulse pressure variation through a temporary increase in tidal volume
Conclusion: In mechanically ventilated patients, our augmented PPV successfully predicted fluid responsiveness in the previously suggested grey zone.Clinical trial registration: ClinicalTrials.gov, NCT02653469. (Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - June 28, 2017 Category: Anesthesiology Source Type: research
Prolonged concurrent hypotension and low bispectral index ( ‘double low’) are associated with mortality, serious complications, and prolonged hospitalization after cardiac surgery
Conclusions: A prolonged concurrent double low, but not a case-averaged double low, was associated with higher morbidity and mortality after cardiac surgery. (Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - June 28, 2017 Category: Anesthesiology Source Type: research
Supraglottic jet oxygenation and ventilation enhances oxygenation during upper gastrointestinal endoscopy in patients sedated with propofol: a randomized multicentre clinical trial
Conclusions. The use of SJOV during upper gastrointestinal endoscopy for patients who are sedated with propofol reduces the incidence of hypoxia, with minor and tolerable adverse events. Supraglottic jet oxygenation and ventilation has a favourable risk-to-benefit ratio and may improve patient safety.Clinical trial registration. NCT02436018. (Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - June 28, 2017 Category: Anesthesiology Source Type: research
Premedication with salbutamol prior to surgery does not decrease the risk of perioperative respiratory adverse events in school-aged children
Conclusions: Premedication with salbutamol to children aged between 6 and 16 years and at high risk of PRAE prior to their surgery did not reduce their risk of PRAE.Trial registration number: ACTRN12612000626864 (www.anzctr.org.au). (Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - June 28, 2017 Category: Anesthesiology Source Type: research
High intraoperative inspiratory oxygen fraction and risk of major respiratory complications
Conclusions. In this analysis of administrative data on file, high intraoperative FIO2 was associated in a dose-dependent manner with major respiratory complications and with 30-day mortality. The effect remained stable in a sensitivity analysis controlled for oxygenation.Clinical trial registration. NCT02399878. (Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - June 28, 2017 Category: Anesthesiology Source Type: research
Impact of sleep deprivation on anaesthesia residents ’ non-technical skills: a pilot simulation-based prospective randomized trial
Conclusions. In this randomized pilot trial, sleep deprivation was associated with impaired non-technical skills of anaesthesia residents in a simulated anaesthesia intraoperative crisis scenario.Trial registration. NCT02622217. (Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - June 28, 2017 Category: Anesthesiology Source Type: research
