Best Practice and Research. Clinical Anaesthesiology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Neuromuscular blockers and reversal agents and their impact on anesthesia practice
Publication date: Available online 2 July 2018Source: Best Practice & Research Clinical AnaesthesiologyAuthor(s): Zdravka Zafirova, Allison DaltonAbstractNeuromuscular blockers have long been an intricate part of the anesthesia regimen. The scientific progress in pharmacology and physiology has strengthened their clinical relevance, has helped to delineate with precision their medical role and has enhanced the safety and effectiveness of their use. New frontiers in research will define further the role of these agents in the modern anaesthesia practice and guide their expanding and discrete clinical applications. (Source: ...
Source: Best Practice and Research Clinical Anaesthesiology - July 10, 2018 Category: Anesthesiology Source Type: research

Update on Nitrous Oxide and Its Use in Anesthesia Practice
Publication date: Available online 2 July 2018Source: Best Practice & Research Clinical AnaesthesiologyAuthor(s): Zdravka Zafirova, Colin Sheehan, Leila HosseinianAbstractNitrous oxide is an anesthetic and analgesic gas with long history of medical applications. It acts on multiple supraspinal and spinal targets, and has utility in a wide range of clinical situations. The relative safety, low incidence and acuity of adverse effects of nitrous oxide, along with the ability to be administered by trained medical providers with varying clinical backgrounds, as well as self-administered by patients, assure its persistent and ex...
Source: Best Practice and Research Clinical Anaesthesiology - July 10, 2018 Category: Anesthesiology Source Type: research

New Benzodiazepines for Sedation
Publication date: Available online 3 July 2018Source: Best Practice & Research Clinical AnaesthesiologyAuthor(s): Elyse M. Cornett, Matthew B. Novitch, Andrew J. Brunk, Kelly S. Davidson, Bethany L. Menard, Richard D. Urman, Alan D. KayeAbstractThere are currently new drugs being developed that have benzodiazepine properties. This review will examine remimazolam, 3-hydroxyphenazapam, Adinazolam, Clonazolam, and Deschloroetizolam as well as other novel agents. All benzodiazepines are protein bound and only moderately lipid soluble. In addition to their baseline properties, they can be enzymatically broken down into active m...
Source: Best Practice and Research Clinical Anaesthesiology - July 10, 2018 Category: Anesthesiology Source Type: research

New Local Anesthetics
Publication date: Available online 3 July 2018Source: Best Practice & Research Clinical AnaesthesiologyAuthor(s): Jarna Shah, Effrossyni Gina Votta-Velis, Alain BorgeatAbstractLocal anesthetics are used for the performance of various regional anesthesia techniques for intraoperative anesthesia and analgesia, as well as for the treatment of acute and chronic pain. Older medications like lidocaine and bupivacaine as well as newer ones such as mepivacaine and ropivacaine are being used successfully for decades. Routes of administration include neuraxial, perineural, intravenous, various infiltrative approaches, topical, and t...
Source: Best Practice and Research Clinical Anaesthesiology - July 10, 2018 Category: Anesthesiology Source Type: research

Adjunct Medications for Peripheral and Neuraxial Anesthesia
Publication date: Available online 3 July 2018Source: Best Practice & Research Clinical AnaesthesiologyAuthor(s): Patrick Ifesinachi Emelife, Matt R. Eng, Bethany L. Menard, Andrew S. Meyers, Elyse M. Cornett, Richard D. Urman, Alan D. KayeAbstractRegional and neuraxial anesthesia have provided a safer perioperative experience, greater satisfaction, reduced opioid consumption, and reduction of pain while minimizing side effects. In this regard, ultrasound technology has aided clinicians in depositing local anesthetic medication in precise proximity to targeted peripheral nerves. There are a plethora of adjuvants that have ...
Source: Best Practice and Research Clinical Anaesthesiology - July 10, 2018 Category: Anesthesiology Source Type: research