Improving female physician's careers in academic medicine: Chances and challenges
Publication date: March 2018Source: Best Practice & Research Clinical Anaesthesiology, Volume 32, Issue 1Author(s): Bettina Pfleiderer, Marina Bortul, Silvia Palmisano, Sibyll Rodde, Joachim HasebrookUniversity hospitals are involved in the care of critically ill patients, pregraduate and postgraduate education, and medical research with an increasing demand on physicians due to a higher burden of disease. The number of female physicians is increasing; however, young female physicians are less willing to work at university hospitals under the given conditions. They often do not find appropriate working conditions in mostly...
Source: Best Practice and Research Clinical Anaesthesiology - July 24, 2018 Category: Anesthesiology Source Type: research

Moving towards a competence centre for geriatric medicine and care: Quality management and human resource management as major support factors
Publication date: March 2018Source: Best Practice & Research Clinical Anaesthesiology, Volume 32, Issue 1Author(s): Kerstin Löffler, Judith Goldgruber, Gerd HartingerChanged employment models, an ageing workforce and demands of new generations are challenging healthcare facilities to go down new paths. Never before have well-qualified staff been as highly sought after within the medical and nursing care sector as they are today.For many years, the Geriatric Health Care Centres of the city of Graz (GGZ)—a large regional health care provider with more than 650 staff across five locations—has focused a lot on the topic o...
Source: Best Practice and Research Clinical Anaesthesiology - July 24, 2018 Category: Anesthesiology Source Type: research

Editorial Board
Publication date: March 2018Source: Best Practice & Research Clinical Anaesthesiology, Volume 32, Issue 1Author(s): (Source: Best Practice and Research Clinical Anaesthesiology)
Source: Best Practice and Research Clinical Anaesthesiology - July 24, 2018 Category: Anesthesiology Source Type: research

Integrating cross-border emergency medicine systems: Securing future preclinical medical workforce for remote medical services
Publication date: March 2018Source: Best Practice & Research Clinical Anaesthesiology, Volume 32, Issue 1Author(s): Tomasz Ucinski, Grzegorz Dolata, Robert Hełminiak, Lutz Fischer, Steffen Fleßa, Bernhard Brehmer, Armin Viert, Volker Grundmann, Sebastian Rehberg, Kathrin Krügel, Maud Partecke, Peter Brinkrolf, Klaus Hahnenkamp, Konrad MeissnerThe European Union intends to enable its citizens to interact across borders in relevant areas of society and culture to further integrate neighboring regions. Medicine has not been at the core of recent EU-funded efforts in central Europe, partially due to significant differences ...
Source: Best Practice and Research Clinical Anaesthesiology - July 24, 2018 Category: Anesthesiology Source Type: research

Pathophysiology of AKI
Publication date: September 2017Source: Best Practice & Research Clinical Anaesthesiology, Volume 31, Issue 3Author(s): Marlies Ostermann, Kathleen LiuAcute kidney injury (AKI) is common in the perioperative and intensive care setting. Although AKI is usually multifactorial, haemodynamic instability, sepsis and drug toxicity are commonly implicated. Independent of the exact aetiology, several different pathophysiologic processes occur simultaneously and in sequence, including endothelial dysfunction, alteration of the microcirculation, tubular injury, venous congestion and intrarenal inflammation. A multitude of different ...
Source: Best Practice and Research Clinical Anaesthesiology - July 10, 2018 Category: Anesthesiology Source Type: research

Keyword index
Publication date: September 2017Source: Best Practice & Research Clinical Anaesthesiology, Volume 31, Issue 3Author(s): (Source: Best Practice and Research Clinical Anaesthesiology)
Source: Best Practice and Research Clinical Anaesthesiology - July 10, 2018 Category: Anesthesiology Source Type: research

Acute kidney injury in pediatric patients
Publication date: September 2017Source: Best Practice & Research Clinical Anaesthesiology, Volume 31, Issue 3Author(s): David M. Kwiatkowski, Scott M. SutherlandAcute kidney injury (AKI) is highly prevalent among hospitalized children, especially those who are critically ill. The incorporation of pediatric elements into consensus definitions has led to a greater understanding of pediatric AKI epidemiology, risk factors, and outcomes. The best available data suggest that AKI occurs in 5% and 27% of non-critically ill and critically ill children, respectively. Additionally, AKI and fluid overload are independently associated...
Source: Best Practice and Research Clinical Anaesthesiology - July 10, 2018 Category: Anesthesiology Source Type: research

Sequelae of AKI
Publication date: September 2017Source: Best Practice & Research Clinical Anaesthesiology, Volume 31, Issue 3Author(s): Samir S. Patel, Carlos E. Palant, Vrinda Mahajan, Lakhmir S. ChawlaLarge epidemiologic studies in a variety of patient populations reveal increased morbidity and mortality that occur months to years after an episode of acute kidney injury (AKI). Even milder forms of AKI have increased associated morbidity and mortality. Residual confounding may account for these findings, but considering the huge number of individuals afflicted with AKI, the sequelae of AKI may be a very large public health burden. AKI ma...
Source: Best Practice and Research Clinical Anaesthesiology - July 10, 2018 Category: Anesthesiology Source Type: research

Renal recovery
Publication date: September 2017Source: Best Practice & Research Clinical Anaesthesiology, Volume 31, Issue 3Author(s): Ivan Göcze, Christina Wiesner, Hans J. Schlitt, Tobias BerglerRecovery patterns after acute kidney injury (AKI) have increasingly become the focus of research, because currently available preventive measures and specific therapeutic intervention are limited. Moreover, changes in renal functional reserve are recognized as a “hidden” indicator of kidney susceptibility to either acute kidney injury or chronic kidney disease. Understanding these phenomena and their association with outcome may enable the...
Source: Best Practice and Research Clinical Anaesthesiology - July 10, 2018 Category: Anesthesiology Source Type: research

Renal replacement therapy and anticoagulation
Publication date: September 2017Source: Best Practice & Research Clinical Anaesthesiology, Volume 31, Issue 3Author(s): Timo Brandenburger, Thomas Dimski, Torsten Slowinski, Detlef Kindgen-MillesToday, up to 20% of all intensive care unit patients require renal replacement therapy (RRT), and continuous renal replacement therapies (CRRT) are the preferred technique. In CRRT, effective anticoagulation of the extracorporeal circuit is mandatory to prevent clotting of the circuit or filter and to maintain filter performance. At present, a variety of systemic and regional anticoagulation modes for CRRT are available. Worldwide,...
Source: Best Practice and Research Clinical Anaesthesiology - July 10, 2018 Category: Anesthesiology Source Type: research

Epidemiology of cardiac surgery-associated acute kidney injury
Publication date: September 2017Source: Best Practice & Research Clinical Anaesthesiology, Volume 31, Issue 3Author(s): Eric A.J. Hoste, Wim VandenbergheAcute kidney injury (AKI) is defined by the KDIGO definition into 3 stages on basis of an increase in serum creatinine or a period of oliguria. AKI is defined as rapid reversal when the episode is 48 h or less. When AKI persists for 7 days or longer, the term acute kidney disease is used. Subclinical AKI is defined by increased concentration of an AKI biomarker, without meeting the KDIGO definition for AKI. In contrast to this, functional AKI is defined by the KDIGO defin...
Source: Best Practice and Research Clinical Anaesthesiology - July 10, 2018 Category: Anesthesiology Source Type: research

Prevention of acute kidney injury
Publication date: September 2017Source: Best Practice & Research Clinical Anaesthesiology, Volume 31, Issue 3Author(s): Melanie Meersch, Stephanie Volmering, Alexander ZarbockAcute kidney injury is a prevalent but underdiagnosed complication that is associated with increased in-hospital morbidity and mortality. The importance of this complication is being increasingly recognized. The lack of timely diagnostic methods and effective preemptive and therapeutic strategies make its perioperative management challenging. To reduce the incidence of acute kidney injury, it is crucial to focus the resources on high-risk patients who...
Source: Best Practice and Research Clinical Anaesthesiology - July 10, 2018 Category: Anesthesiology Source Type: research

Impact of e-alert systems on the care of patients with acute kidney injury
Publication date: September 2017Source: Best Practice & Research Clinical Anaesthesiology, Volume 31, Issue 3Author(s): Crystal M. Breighner, Kianoush B. KashaniWith the recent advancement in electronic health record systems and meaningful use of information technology incentive programs (i.e., the American Recovery and Reinvestment Act, the Health Information Technology for Economic and Clinical Health Act, and the Centers for Medicare & Medicaid Services), interest in clinical decision support systems has risen. These systems have been used to examine a variety of different syndromes with variable reported effects. In re...
Source: Best Practice and Research Clinical Anaesthesiology - July 10, 2018 Category: Anesthesiology Source Type: research

Impact of volume status and volume therapy on the kidney
Publication date: September 2017Source: Best Practice & Research Clinical Anaesthesiology, Volume 31, Issue 3Author(s): David A. Roberts, Andrew D. ShawVolume resuscitation to correct hypotension in surgical and critically ill patients is a common practice. Available evidence suggests that iatrogenic volume overload is associated with worse outcomes in established acute kidney injury. Intraoperative arterial hypotension is associated with postoperative renal dysfunction, and prompt correction with fluid management protocols that combine inotrope infusions with volume therapy targeted to indices of volume responsiveness sho...
Source: Best Practice and Research Clinical Anaesthesiology - July 10, 2018 Category: Anesthesiology Source Type: research

Biomarkers in acute kidney injury (AKI)
Publication date: September 2017Source: Best Practice & Research Clinical Anaesthesiology, Volume 31, Issue 3Author(s): Su Hooi Teo, Zoltán Huba EndreAcute kidney injury is common in critically ill patients and portends a significant impact on mortality, progressive chronic kidney disease, and cardiovascular disease and mortality. Though most physicians alter therapy depending on changes in serum creatinine, this often represents delayed intervention. Various AKI biomarkers have been discovered and validated to improve timely detection, differentiation and stratification into risk groups for progressive renal decline, nee...
Source: Best Practice and Research Clinical Anaesthesiology - July 10, 2018 Category: Anesthesiology Source Type: research