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Artificial Organs, Ahead of Print. (Source: Artificial Organs)
Source: Artificial Organs - March 6, 2018 Category: Transplant Surgery Source Type: research
Mechanical and Chemical Predifferentiation of Mesenchymal Stem Cells Into Cardiomyocytes and Their Effectiveness on Acute Myocardial Infarction
Abstract
Myocardial infarction is one of the leading causes of death all over the world. Mesenchymal stem cells (MSCs) transplantation has shown a promising potential to recovery of ischemic heart disease due to their capability in differentiating into cardiac cells. However, various investigations have been performed to optimize the efficacy of cardiac cell therapy in recent years. Here, we sought to interrogate the effect of autologous transplantation of undifferentiated and predifferentiated adipose and bone marrow‐derived MSCs in a rabbit model of myocardial infarction and also to investigate whether cardiac function...
Source: Artificial Organs - March 6, 2018 Category: Transplant Surgery Authors: Baharak Abd Emami, Elena Mahmoudi, Mohammad Ali Shokrgozar, Mohammad Mehdi Dehghan, Saeed Farzad Mohajeri, Nooshin Haghighipour, Seyyed Hossein Marjanmehr, Mohammad Molazem, Susan Amin, Hossein Gholami Tags: Main Text Source Type: research
Meta ‐Analysis of Time in Therapeutic Range in Continuous‐Flow Left Ventricular Assist Device Patients Receiving Warfarin
Abstract
Continuous‐flow left ventricular assist devices (CF‐LVADs) prolong survival in advanced heart failure patients. Anticoagulation control is critical in CF‐LVAD patients due to increased thromboembolic and bleeding risk. We assessed the quality of INR control in CF‐LVAD patients measured by time in therapeutic range (TTR). We performed a systematic literature search of MEDLINE and SCOPUS through July 2017 to identify studies evaluating TTR in anticoagulated adult CF‐LVAD patients. Data on key characteristics and the TTR end point were then extracted from each study by two investigators using a standardized...
Source: Artificial Organs - March 6, 2018 Category: Transplant Surgery Authors: Brandon K. Martinez, Brenda Yik, Raymond Tran, Sabrina Ilham, Craig I. Coleman, Douglas L. Jennings, William L. Baker Tags: Main Text Source Type: research
The Progress in the Novel Pediatric Rotary Blood Pump Sputnik Development
In this study, a mock circulatory system (MCS) allowing simulation of physiological cardiovascular characteristics was used to investigate the interaction of the Sputnik PRBP with the cardiovascular system. MCS allows reproducing the Frank‐Starling autoregulation mechanism of the heart. PRBP behavior was tested in the speed range of 6 000 to 15 000 rpm. Decreased contractility can be expressed in a stroke volume decrease approximately from 18 to 4 mL and ventricle systolic pressure decrease approximately from 92 to 20 mm Hg. The left ventricle becomes fully supported at a pump speed of 10 000 rpm. At a pump speed of 1...
Source: Artificial Organs - March 6, 2018 Category: Transplant Surgery Authors: Dmitry Telyshev, Maxim Denisov, Alexander Pugovkin, Sergey Selishchev, Igor Nesterenko Tags: Main Text Source Type: research
Synchronized Pulsatile Flow With Low Systolic Output From Veno ‐Arterial Extracorporeal Membrane Oxygenation Improves Myocardial Recovery After Experimental Cardiac Arrest in Pigs
Abstract
Circulatory failure following cardiac arrest (CA) requires catecholamine support and occasionally veno‐arterial extracorporeal membrane oxygenation (vaECMO). VaECMO‐generated blood flow is continuous and retrograde, increasing ventricular stroke work. Our aim was to assess the benefit of a device generating a pulsatile vaECMO flow synchronized with the heart rhythm lowering systolic vaECMO output on the left ventricular ejection fraction (LVEF) and pulmonary capillary pressure (Pcap) after CA. This experimental randomized study in pigs compared standard nonpulsatile vaECMO (control) with pulsatile synchronized...
Source: Artificial Organs - March 6, 2018 Category: Transplant Surgery Authors: Sebastian Voicu, Georgios Sideris, Jean ‐Guillaume Dillinger, Demetris Yannopoulos, Nicolas Deye, Chantal Kang, Michel Bonneau, Jason Bartos, Antoni Kedra, Sophie Bailliart, Adrien Pasteur‐Rousseau, Guy Amah, Philippe Bonnin, Jacques Callebert, Patric Tags: Main Text Source Type: research
Formation of Blood Foam in the Air Trap During Hemodialysis Due to Insufficient Automatic Priming of Dialyzers
In conclusion, this study urgently calls attention to blood foam development in the venous air trap when using Artis devices and priming software 8.15 in combination with Fresenius dialyzers. Updated auto‐priming software (version 8.21) of Artis should be requested to reduce the extent of foam for the Fresenius dialyzers. Other interactions may also be present. We recommend further studies to clarify these problems. Meanwhile caution is warranted for the combined use of dialysis devices and dialyzers with incompatible automatic priming. (Source: Artificial Organs)
Source: Artificial Organs - March 1, 2018 Category: Transplant Surgery Authors: Per Jonsson, Lorentz Lindmark, Jan Axelsson, Lars Karlsson, Lennart Lundberg, Bernd Stegmayr Tags: Main Text Source Type: research
Ulnar Nerve Conduction Block Using Surface Kilohertz Frequency Alternating Current: A Feasibility Study
Abstract
The aim of this study was to test the effects of kilohertz frequency alternating current (KHFAC) surface stimulation applied to the ulnar nerve on force and myoelectrical activity of the abductor digiti minimi (ADM) muscle. Eighteen healthy volunteers (age: 27.6 ± 7.9 years; 10 males, 8 females) were included in the study. Each subject participated in one session during which a biphasic 7 kHz rectangular pulse was delivered above the medial epicondyle of the humerus to induce ulnar nerve blocking. ADM electromyographic (EMG) activity and contraction force were measured before (Pre), immediately after, and fol...
Source: Artificial Organs - March 1, 2018 Category: Transplant Surgery Authors: Shmuel Springer, Zvi Kozol, Zvi Reznic Tags: Thoughts and Progress Source Type: research
Contemporary Oxygenator Design: Shear Stress ‐Related Oxygen and Carbon Dioxide Transfer
Artificial Organs, EarlyView. (Source: Artificial Organs)
Source: Artificial Organs - February 23, 2018 Category: Transplant Surgery Source Type: research
In Vitro Evaluation of ECG ‐Synchronized Pulsatile Flow Using the i‐cor Diagonal Pump in Neonatal and Pediatric ECLS Systems
Artificial Organs, EarlyView. (Source: Artificial Organs)
Source: Artificial Organs - February 23, 2018 Category: Transplant Surgery Source Type: research
Bridging to a Long ‐Term Ventricular Assist Device With Short‐Term Mechanical Circulatory Support
Artificial Organs, EarlyView. (Source: Artificial Organs)
Source: Artificial Organs - February 23, 2018 Category: Transplant Surgery Source Type: research
