Acute effect of a resistance exercise session on markers of cartilage breakdown and inflammation in women with rheumatoid arthritis
ConclusionWomen with and without RA have similar changes in response to a RE session in levels of inflammation biomarkers, but not of cartilage breakdown. IL‐10 and IL‐1ra increased after the RE session, indicating that RE may have an acute anti‐inflammatory effect. Additional studies are necessary to clarify if repeated RE sessions can have long‐term anti‐inflammatory effects and the possible clinical repercussions of this cartilage breakdown characteristic in response to exercise in RA patients. (Source: APLAR Journal of Rheumatology)
Source: APLAR Journal of Rheumatology - November 3, 2017 Category: Rheumatology Authors: Ana Carolina Pereira Nunes Pinto, Jamil Natour, Charlles Heldan de Moura Castro, Marina Eloi, Imp ério Lombardi Junior Tags: Original Article Source Type: research

Two ‐year persistence of golimumab as second‐line biologic agent in rheumatoid arthritis as compared to other subcutaneous tumor necrosis factor inhibitors: real‐life data from the LORHEN registry
ConclusionsOur real‐life data confirmed switching to a second TNFi as a good option for treating first‐line TNFi failures in RA, especially in combination with sDMARDs. Second‐line golimumab showed an overall better 2‐year drug survival compared with adalimumab and etanercept. (Source: APLAR Journal of Rheumatology)
Source: APLAR Journal of Rheumatology - October 30, 2017 Category: Rheumatology Authors: Ennio G. Favalli, Luigi Sinigaglia, Andrea Becciolini, Vittorio Grosso, Roberto Gorla, Chiara Bazzani, Fabiola Atzeni, Pier C. Sarzi Puttini, Enrico Fusaro, Raffaele Pellerito, Roberto Caporali Tags: Original Article Source Type: research

Generalised joint hypermobility and knee joint hypermobility: prevalence, knee joint symptoms and health ‐related quality of life in a Danish adult population
International Journal of Rheumatic Diseases, EarlyView. (Source: APLAR Journal of Rheumatology)
Source: APLAR Journal of Rheumatology - October 27, 2017 Category: Rheumatology Source Type: research

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International Journal of Rheumatic Diseases, Ahead of Print. (Source: APLAR Journal of Rheumatology)
Source: APLAR Journal of Rheumatology - October 27, 2017 Category: Rheumatology Source Type: research

A systematic review of the epidemiology, disease characteristics and management of systemic sclerosis in Australian adults
ConclusionInformation on SSc in Australia, particularly unmet healthcare needs, HRQoL and economic burden, is limited. As a heterogenous condition, SSc requires a multi‐disciplinary approach to care. Research aimed at quantifying HRQoL and burden of disease in Australia is essential for advocacy and resource allocation. (Source: APLAR Journal of Rheumatology)
Source: APLAR Journal of Rheumatology - October 27, 2017 Category: Rheumatology Authors: Kathleen Morrisroe, Wendy Stevens, Susanna Proudman, Mandana Nikpour Tags: Original Article Source Type: research