Dosing down and then discontinuing biologic therapy in rheumatoid arthritis: a review of the literature
ConclusionIn patients who have achieved LDA or remission, down‐titration and discontinuation of bDMARD therapy may be attempted, with careful monitoring. However, it is likely that some patients will flare, and it is not known how to predict these patients. (Source: APLAR Journal of Rheumatology)
Source: APLAR Journal of Rheumatology - December 4, 2017 Category: Rheumatology Authors: Der ‐Yuan Chen, Chak Sing Lau, Bassel Elzorkany, Ping‐Ning Hsu, Sonja Praprotnik, Radu Vasilescu, Lisa Marshall, Lyndon Llamado Tags: Review Article Source Type: research
Hyperuricemia in Asian psoriatic arthritis patients
ConclusionA significant proportion of PsA patients had asymptomatic hyperuricemia. It was closely related with BMI, which represented metabolic dysregulation; but not with severity of skin disease, joint involvement or renal function. (Source: APLAR Journal of Rheumatology)
Source: APLAR Journal of Rheumatology - December 1, 2017 Category: Rheumatology Authors: Tin Lok Lai, Cheuk Wan Yim, Pui Yan Wong, Man Chi Leung, Woon Leung Ng Tags: Original Article Source Type: research
Screening for latent tuberculosis infection among patients with rheumatoid arthritis in the era of biologics and targeted synthetic disease ‐modifying anti‐rheumatic drugs in India, a high‐burden TB country: The importance of Mantoux and Quantiferon‐TB Gold tests
ConclusionCombined a‐TST with QFTG testing gave 43% positivity among RA patients, which is close to the reported ~ 40% Mantoux positivity in the general population. Therefore, this method for the screening of LTBI in Indian patients with RA being considered for tumor necrosis factor alpha treatment could be satisfactory for offsetting TB flare. It may apply to other high‐burden TB countries around the world. (Source: APLAR Journal of Rheumatology)
Source: APLAR Journal of Rheumatology - December 1, 2017 Category: Rheumatology Authors: Anand N. Malaviya, Vishal K. Aggarwal, Roopa Rawat, Sadhana Baghel, Ravita Thakran, Qamar Zaheer, Shriram Garg, Sanjiv Kapoor Tags: Original Article Source Type: research
Anti ‐transcription intermediary factor 1γ antibody titer correlates with clinical symptoms in a patient with recurrent dermatomyositis associated with ovarian cancer
(Source: APLAR Journal of Rheumatology)
Source: APLAR Journal of Rheumatology - December 1, 2017 Category: Rheumatology Authors: Mika Teraishi, Kimiko Nakajima, Tatsushi Ishimoto, Mayuko Yamamoto, Nagamasa Maeda, Yoshinao Muro, Shigetoshi Sano Tags: Correspondence Source Type: research
Concordance and correlation of activity indices in patients with rheumatoid arthritis in northwestern Colombia: A cross ‐sectional study
International Journal of Rheumatic Diseases, EarlyView. (Source: APLAR Journal of Rheumatology)
Source: APLAR Journal of Rheumatology - November 19, 2017 Category: Rheumatology Source Type: research
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International Journal of Rheumatic Diseases, Ahead of Print. (Source: APLAR Journal of Rheumatology)
Source: APLAR Journal of Rheumatology - November 19, 2017 Category: Rheumatology Source Type: research
Professor Tomisaku Kawasaki, my teacher and a friend : a tribute
(Source: APLAR Journal of Rheumatology)
Source: APLAR Journal of Rheumatology - November 19, 2017 Category: Rheumatology Authors: Hirohisa Kato Tags: Special Issue ‐ Kawasaki Disease Source Type: research
Concordance and correlation of activity indices in patients with rheumatoid arthritis in northwestern Colombia: A cross ‐sectional study
ConclusionClinimetric indices had high concordance and correlation, especially for rheumatoid arthritis patients in remission or low disease activity, without being interchangeable among them. (Source: APLAR Journal of Rheumatology)
Source: APLAR Journal of Rheumatology - November 19, 2017 Category: Rheumatology Authors: Ricardo Restrepo ‐Correa, Libia M. Rodríguez‐Padilla, Aura L. Zapata‐Castellanos, Andrea Ocampo, Juan J. García, Carolina Muñoz‐Grajales, Luis F. Pinto‐Peñaranda, Javier D. Márquez‐Hernández, Miguel A. Mesa‐Navas, Carlos J. Velásquez Tags: Original Article Source Type: research
Kawasaki disease – a parent's perspective
(Source: APLAR Journal of Rheumatology)
Source: APLAR Journal of Rheumatology - November 19, 2017 Category: Rheumatology Authors: Consuelo Elliott Tags: Special Issue – Kawasaki Disease Source Type: research
The genetics of Kawasaki disease
Abstract
Kawasaki disease (KD) is a complex disorder which affects genetically susceptible infants and children. Several susceptibility genes (e.g., ITPKC, CASP3, CD40 and ORAI) and chromosomal regions have been identified through genome‐wide association and genome‐wide linkage studies to have association with KD. Knowledge of susceptibility genes involved in the pathogenesis of KD may provide new insights into diagnosis and treatment of this condition. However, there is much that we still do not know about the genetic basis of KD. (Source: APLAR Journal of Rheumatology)
Source: APLAR Journal of Rheumatology - November 19, 2017 Category: Rheumatology Authors: Yoshihiro Onouchi Tags: Special Issue – Kawasaki Disease Source Type: research
The role of echocardiography in Kawasaki disease
Abstract
Kawasaki disease (KD) is an acute, self‐limited vasculitis affecting young children. It can result in coronary artery abnormalities in a significant proportion of patients, especially if the diagnosis is missed or treatment gets delayed. Echocardiography is the imaging modality of choice for detection of coronary artery abnormalities and assessment of myocardial function. It is also useful for characterization and risk stratification of patients with KD. Echocardiography should be performed at the time of diagnosis and then again at 1–2 weeks and 4–6 weeks after treatment, for uncomplicated cases who do not ...
Source: APLAR Journal of Rheumatology - November 19, 2017 Category: Rheumatology Authors: Brian W. McCrindle, Barbara Cifra Tags: Special Issue – Kawasaki Disease Source Type: research
History of the worldwide emergence of Kawasaki disease
Abstract
Dr. Kawasaki saw his first case of the disease that would come to bear his name in 1961. His meticulous description of the clinical syndrome persists as the case definition to the present day. This review chronicles the emergence and recognition of Kawasaki disease in Asia and Western countries and articulates the old disease/new disease controversy. (Source: APLAR Journal of Rheumatology)
Source: APLAR Journal of Rheumatology - November 19, 2017 Category: Rheumatology Authors: Jane C. Burns Tags: Special Issue ‐ Kawasaki Disease Source Type: research
Kawasaki disease: epidemiology and the lessons from it
Abstract
A half of century has passed since Dr. Tomisaku Kawasaki reported his 50 cases with Kawasaki disease (KD) in 1967. Since then, more than 300 000 cases have been reported to the nationwide epidemiologic surveys in Japan. However, the etiology and risk factors of the disease are still unknown. In this paper, the author emphasizes that the epidemiology of KD may indicate an infectious agent to be a potential trigger of disease in susceptible children. (Source: APLAR Journal of Rheumatology)
Source: APLAR Journal of Rheumatology - November 8, 2017 Category: Rheumatology Authors: Yosikazu Nakamura Tags: Special Issue ‐ Kawasaki Disease Source Type: research
Differences between adult and pediatric onset Henoch ‐Schonlein purpura from North India
ConclusionCompared to children, adults with HSP seldom have abdominal pain as the first clinical manifestation while joint involvement is seen more commonly in them during the disease course. (Source: APLAR Journal of Rheumatology)
Source: APLAR Journal of Rheumatology - November 8, 2017 Category: Rheumatology Authors: Vikas Gupta, Amita Aggarwal, Ranjan Gupta, Abhra Chandra Chowdhury, Vikas Agarwal, Able Lawrence, Ramnath Misra Tags: Original Article Source Type: research
Kawasaki disease – the journey over 50 years: 1967–2017
(Source: APLAR Journal of Rheumatology)
Source: APLAR Journal of Rheumatology - November 8, 2017 Category: Rheumatology Authors: Tomisaku Kawasaki, Surjit Singh Tags: Special Issue ‐ Kawasaki Disease Source Type: research
