World Kidney Day 2020: Advances in Preventive Nephrology.
PMID: 32419005 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - March 31, 2020 Category: General Medicine Authors: Kwek JL, Kee TYS Tags: Ann Acad Med Singapore Source Type: research

Sedation and Delirium in the Intensive Care Unit-A Practice-Based Approach.
CONCLUSION: More effort is required to develop a practical, time-weighted sedation scoring system. Emphasis on a balanced, multimodal appraoch that targets light sedation from the early phase of acute critical illness is important to achieve optimal sedation, lower mortality, shorten time on ventilator and reduce delirium. PMID: 32419006 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - March 31, 2020 Category: General Medicine Authors: Wong IMJ, Thangavelautham S, Loh SCH, Ng SY, Murfin B, Shehabi Y Tags: Ann Acad Med Singapore Source Type: research

Emerging Treatment Options for Migraine.
Abstract Migraine is one of top 5 medical conditions that contribute to Years Lived with Disability and affects approximately 1 billion people from around the world. To date, preventive treatment and acute therapies for migraine are limited, have undesirable side effects and are poorly tolerated in patients. In the last few decades, considerable advances in our understanding of migraine and its pathophysiology have paved the way for the development of targeted treatment options. Calcitonin gene-related peptide (CGRP) plays an integral role in the neurobiology of migraine, and new classes of drugs that targ...
Source: Annals of the Academy of Medicine, Singapore - March 31, 2020 Category: General Medicine Authors: Zhao YJ, Ong JJY, Goadsby PJ Tags: Ann Acad Med Singapore Source Type: research

The Link Between Amitriptyline and Movement Disorders: Clinical Profile and Outcome.
CONCLUSION: Amitriptyline is associated with various movement disorders, particularly myoclonus, dystonia and dyskinesias. Stutters and restless legs syndrome are some of the less common associations. PMID: 32419008 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - March 31, 2020 Category: General Medicine Authors: Rissardo JP, Caprara ALF Tags: Ann Acad Med Singapore Source Type: research

Artificial Intelligence and Medical Innovation.
PMID: 32419009 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - March 31, 2020 Category: General Medicine Authors: Tan EC Tags: Ann Acad Med Singapore Source Type: research

Anxiety and Morale in Front-Line Healthcare Workers During the Coronavirus Disease 2019 (COVID-19) Outbreak at the National Screening Centre in Singapore.
PMID: 32419010 [PubMed - indexed for MEDLINE] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - March 31, 2020 Category: General Medicine Authors: Goh SSN, Chia MYC Tags: Ann Acad Med Singapore Source Type: research

Decision-Making in Dementia Care: a Qualitative Study of Chinese Family Caregivers in Singapore.
PMID: 32419011 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - March 31, 2020 Category: General Medicine Authors: Tan LL, Ong PS, Ng LL, Ng WF, Wong HK, Sim ACC Tags: Ann Acad Med Singapore Source Type: research

Indurated Skin and Iron Overload-the Missing Link.
PMID: 32419012 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - March 31, 2020 Category: General Medicine Authors: Cao T, Chia HY, Lee JSS, Chong WS, Heng YK Tags: Ann Acad Med Singapore Source Type: research

Laparoscopic Tubal Re-Anastomosis or IVF in Previously Ligated Patients: A Comparison of Fertility Outcomes and Survey of Patient Attitudes.
CONCLUSIONS: For women less than 40 years of age, desiring fertility after tubal ligation, laparoscopic tubal re-anastomosis offers better live birth rates and cost-effectiveness. Patients in Singapore are equivocal as to their preference after education regarding the choices. Thus laparoscopic tubal re-anastomosis remains a viable alternative to IVF treatment. PMID: 32296806 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - March 31, 2020 Category: General Medicine Authors: Chua KH, Chan JKY, Liu S, Tan TY, Phoon JWL, Viardot-Foucault VC, Nadarajah S, Tan HH Tags: Ann Acad Med Singapore Source Type: research

Recovery in Psychosis: Perspectives of Clients With First Episode Psychosis.
CONCLUSIONS: The emergent themes provide an understanding of the meaning of recovery to persons with first episode psychosis, their experiences as they proceed with their recovery journey and factors they found helpful. The importance of acceptance of the condition and the personal role the individual plays in his or her own recovery was evident in the narratives of the participants. The study suggests a need to incorporate recovery-relevant approaches right from the first episode of psychosis. PMID: 32296807 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - March 31, 2020 Category: General Medicine Authors: Vaingankar JA, Cetty L, Subramaniam M, Lee YY, Chong SA, Lee H, Verma S Tags: Ann Acad Med Singapore Source Type: research

Extracorporeal Membrane Oxygenation for Severe Respiratory Failure during Respiratory Epidemics and Pandemics: A Narrative Review.
CONCLUSION: The role of ECMO in managing ARDS during respiratory pandemics continues to grow. This is supported by efforts to redefine optimal ventilatory strategies, reinforce infection control measures and enhance patient selection. PMID: 32296808 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - March 31, 2020 Category: General Medicine Authors: Lim JKB, Qadri SK, Toh TSW, Lin CB, Mok YH, Lee JH Tags: Ann Acad Med Singapore Source Type: research

Artificial Intelligence: a Singapore Response.
PMID: 32296809 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - March 31, 2020 Category: General Medicine Authors: Ooi GSK, Liew C, Ting DSW, Lim TCC Tags: Ann Acad Med Singapore Source Type: research

A "Saga" of Adenanthera Pavonina Seed Ingestion in a Toddler.
PMID: 32296810 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - March 31, 2020 Category: General Medicine Authors: James V, Warier A, Ong GY Tags: Ann Acad Med Singapore Source Type: research

Cup-Disc Ratio Grading.
PMID: 32246705 [PubMed - as supplied by publisher] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - January 31, 2020 Category: General Medicine Authors: Aquino MC, Chew PT Tags: Ann Acad Med Singapore Source Type: research

Bleeding Complications and Adverse Events After Desmopressin Acetate for Percutaneous Renal Transplant Biopsy.
CONCLUSION: Prophylactic desmopressin for renal allograft biopsy may be associated with significant hyponatraemia but its effect on bleeding risk is unclear. Fluid restriction (where feasible) should be recommended when desmopressin is used during renal allograft biopsy. A randomised controlled trial is needed to clarify these outcomes. PMID: 32246706 [PubMed - as supplied by publisher] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - January 31, 2020 Category: General Medicine Authors: Ho QY, Lim CC, Thangaraju S, Siow B, Chin YM, Hao Y, Lee PH, Foo M, Tan CS, Kee T Tags: Ann Acad Med Singapore Source Type: research